ChemicalBook > CAS DataBase List > PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

Product Name
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
CAS No.
217082-60-5
Chemical Name
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
Synonyms
Pyr-apelin-13;[PYR1]-APELIN-13;(Glp1)-Apelin-13;[pGlu1]-Apelin-13;{Glp}-RPRLSHKGPMPF;PYR-RPRLSHKGPMPF-OH;3-Dimethyluric acid;[PE]APELIN-13, HUMAN, BOVINE;(GLP1)-APELIN-13, HUMAN, BOVINE;(PYR1)-APELIN-13 (HUMAN, BOVINE)
CBNumber
CB1113712
Molecular Formula
C69H108N22O16S
Formula Weight
1533.8
MOL File
217082-60-5.mol
More
Less

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Property

Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka
3.56±0.10(Predicted)
form 
Powder
color 
White to off-white
Water Solubility 
Soluble to 1 mg/ml in sterile water
Sequence
Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Alfa Aesar
Product number
J66114
Product name
[Glp1]-Apelin-13, human, bovine
Packaging
0.5mg
Price
$69.7
Updated
2021/12/16
Alfa Aesar
Product number
J66114
Product name
[Glp1]-Apelin-13, human, bovine
Packaging
1mg
Price
$94.3
Updated
2021/12/16
Cayman Chemical
Product number
15590
Product name
(Glp1)-Apelin-13
Purity
≥95%
Packaging
1mg
Price
$109
Updated
2021/12/16
Tocris
Product number
2420
Product name
[Pyr1]-Apelin-13
Packaging
1
Price
$192
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP109298
Product name
(Pyr 1)-Apelin-13
Packaging
2mg
Price
$273
Updated
2021/12/16
More
Less

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemical Properties,Usage,Production

Uses

The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 , apelin-17, and apelin-13 , respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. (Glp1)-Apelin-13 is a pyroglutamylated form of apelin-13, in that the N-terminal glutamine residue is cyclized to pyroglutamic acid. Like apelin-13, this compound is a potent APJ receptor agonist (EC50 = 0.30 nM). (Glp1)-Apelin-13 is the major apelin isoform in the plasma of healthy human subjects. It can have vasoconstrictor and antipyretic effects in vitro and in vivo.

Definition

ChEBI: P-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe is a thirteen-membered polypeptide consisting of p-Glu, Arg, Pro, Arg, Leu, Ser, His, Lys, Gly, Pro, Met, Pro and Phe residues joined in sequence. It has a role as an apoptosis inhibitor, a neuroprotective agent and a human metabolite. It is a tautomer of a [Pyr1]apelin-13(2+).

storage

Store at -20°C

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Suppliers

China 106 France 1 Germany 1 Japan 2 The Netherlands 1 United Kingdom 2 United States 15 USA 1 Global 129
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7295
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-025-58361106-805-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9980
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4811
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
6968
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921
Email
sales1@gotopbio.com
Country
CHINA
ProdList
2609
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22787
Advantage
58
Shanghai Longyu Biotechnology Co., Ltd.
Tel
+8619521488211
Fax
+86 15821988213
Email
info@longyupharma.com
Country
China
ProdList
2542
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39894
Advantage
58
Nanjing chengqimei Biotechnology Co., Ltd
Tel
19850819832
Email
2173594524@qq.com
Country
China
ProdList
2638
Advantage
58
Gill polypeptide biopharmaceutical (dalian) co., LTD
Tel
021-61263455 13167021076
Email
amy@glschina.com
Country
China
ProdList
8744
Advantage
58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
Country
China
ProdList
14081
Advantage
58
Nanjing TGpeptide Biotechnology Co.,Ltd.
Tel
18115476705
Email
sales@tgpeptide.com
Country
China
ProdList
3058
Advantage
58
Ontores Biotech
Tel
0571-88760729 18072970094
Email
supports@ontorespeptide.com
Country
China
ProdList
2696
Advantage
58
Henan Weitesi Chemical Technology Co. LTD
Tel
0371-0371-55135753 18003832934
Fax
QQ：2853979818
Email
2853979818@qq.com
Country
China
ProdList
9989
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921 13735575465
Email
sales1@gotopbio.com
Country
China
ProdList
2890
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31121
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24995
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
13675144456
Email
alan.chow@synzest.com
Country
China
ProdList
9470
Advantage
58
Nanjing Yuanpeptide Biotech Co.，Ltd.
Tel
18168071971
Email
support@yuan-peptide.com
Country
China
ProdList
2978
Advantage
58
Chengdu Jinglin Biotechnology Co., Ltd.
Tel
17711399154
Email
3211919385@qq.com
Country
China
ProdList
1815
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-88211921 15572296305
Email
sales4@gotopbio.com
Country
China
ProdList
5178
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6659
Advantage
58
Hangzhou Baige Pharmaceutical Technology Co. , Ltd.
Tel
0571-85350119 15888826472
Email
15888826472@163.com
Country
China
ProdList
2729
Advantage
58
Shanghai HongTide Biotechnology Co.,Ltd.
Tel
19961912513
Email
sales@hongtide.com
Country
China
ProdList
4604
Advantage
58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
Tel
13770887460
Email
wenxi@jszkhy.com
Country
China
ProdList
1349
Advantage
58
Combio (Suzhou) Ltd.
Tel
0512-51886999 17706251929
Email
office@combiosz.com
Country
China
ProdList
2980
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564
Email
August@easycdmo.com
Country
China
ProdList
10030
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29979
Advantage
58
Shanghai Toyang Biotechnology Co., LTD
Tel
021-59555769 13524932310
Fax
021-50342869
Email
1405894150@qq.com
Country
China
ProdList
8221
Advantage
58
Nanjing Yushengkang Biotechnology Co., Ltd
Tel
13327808530
Email
2670965693@qq.com
Country
China
ProdList
2179
Advantage
58
Zhejiang Jiekun Biotechnology Co., Ltd
Tel
0571-88211951 13735575465
Email
sales1@gotopbio.com
Country
China
ProdList
4904
Advantage
58
Wuhan Peptide Core Biotechnology Co., Ltd
Tel
027-65317797 13667154760
Email
1096814016@qq.com
Country
China
ProdList
10120
Advantage
58
Taiyuan Bailihengkang Biotechnology Co., Ltd
Tel
19135651983 19135651983
Email
18611134419@163.com
Country
China
ProdList
4416
Advantage
58
Phygene
Tel
18059081430
Email
2070812664@qq.com
Country
China
ProdList
1232
Advantage
58
More
Less

View Lastest Price from PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH manufacturers

Career Henan Chemical Co
Product
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH 217082-60-5
Price
US $3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11

217082-60-5, PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OHRelated Search:

Chromium picolinate H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

  • (GLP1)-APELIN-13, HUMAN, BOVINE
  • GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
  • (Glp1)-Apelin-13
  • 5-Oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine
  • Pyr-apelin-13
  • GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE: GRPRLSHKGPMPF
  • [PE]APELIN-13, HUMAN, BOVINE
  • PYR-RPRLSHKGPMPF-OH
  • PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
  • PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
  • [PYR1]-APELIN-13
  • (PYR1)-APELIN-13 (HUMAN, BOVINE)
  • (PYR1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT)
  • [PGLU1]APELIN (24-36), HUMAN, BOVINE
  • PGLU-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
  • [Pyr1]-Apelin-13,XRPRLSHKGPMPF,[pGlu1]-Apelin-13, >98%
  • [pGlu1]-Apelin-13
  • L-Phenylalanine, 5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-
  • PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH USP/EP/BP
  • 3-Dimethyluric acid
  • (Pyr?)-Apelin-13 (human, bovine, mouse, rat) acetate salt
  • [Pyr1]-Apelin-13 trifluoroacetate salt
  • {Glp}-RPRLSHKGPMPF
  • [Pyr1]-Apelin 13, endogenous apelin receptor (APJ) agonist
  • 217082-60-5
  • C69H108N22O16S
  • peptide