ChemicalBook > CAS DataBase List > PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

Product Name
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
CAS No.
217082-60-5
Chemical Name
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
Synonyms
Pyr-apelin-13;[PYR1]-APELIN-13;(Glp1)-Apelin-13;[pGlu1]-Apelin-13;{Glp}-RPRLSHKGPMPF;PYR-RPRLSHKGPMPF-OH;3-Dimethyluric acid;[PE]APELIN-13, HUMAN, BOVINE;(GLP1)-APELIN-13, HUMAN, BOVINE;(PYR1)-APELIN-13 (HUMAN, BOVINE)
CBNumber
CB1113712
Molecular Formula
C69H108N22O16S
Formula Weight
1533.8
MOL File
217082-60-5.mol
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PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Property

Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka
3.56±0.10(Predicted)
form 
Powder
Water Solubility 
Soluble to 1 mg/ml in sterile water
Sequence
Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J66114
Product name
[Glp1]-Apelin-13, human, bovine
Packaging
0.5mg
Price
$69.7
Updated
2021/12/16
Alfa Aesar
Product number
J66114
Product name
[Glp1]-Apelin-13, human, bovine
Packaging
1mg
Price
$94.3
Updated
2021/12/16
Cayman Chemical
Product number
15590
Product name
(Glp1)-Apelin-13
Purity
≥95%
Packaging
1mg
Price
$109
Updated
2021/12/16
Tocris
Product number
2420
Product name
[Pyr1]-Apelin-13
Packaging
1
Price
$192
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP109298
Product name
(Pyr 1)-Apelin-13
Packaging
2mg
Price
$273
Updated
2021/12/16
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PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemical Properties,Usage,Production

Uses

The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 , apelin-17, and apelin-13 , respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. (Glp1)-Apelin-13 is a pyroglutamylated form of apelin-13, in that the N-terminal glutamine residue is cyclized to pyroglutamic acid. Like apelin-13, this compound is a potent APJ receptor agonist (EC50 = 0.30 nM). (Glp1)-Apelin-13 is the major apelin isoform in the plasma of healthy human subjects. It can have vasoconstrictor and antipyretic effects in vitro and in vivo.

Definition

ChEBI: P-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe is a thirteen-membered polypeptide consisting of p-Glu, Arg, Pro, Arg, Leu, Ser, His, Lys, Gly, Pro, Met, Pro and Phe residues joined in sequence. It has a role as an apoptosis inhibitor, a neuroprotective agent and a human metabolite. It is a tautomer of a [Pyr1]apelin-13(2+).

storage

Store at -20°C

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH manufacturers

Career Henan Chemical Co
Product
PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH 217082-60-5
Price
US $3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-11

217082-60-5, PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OHRelated Search:


  • (GLP1)-APELIN-13, HUMAN, BOVINE
  • GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
  • (Glp1)-Apelin-13
  • 5-Oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine
  • Pyr-apelin-13
  • GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE: GRPRLSHKGPMPF
  • [PE]APELIN-13, HUMAN, BOVINE
  • PYR-RPRLSHKGPMPF-OH
  • PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
  • PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
  • [PYR1]-APELIN-13
  • (PYR1)-APELIN-13 (HUMAN, BOVINE)
  • (PYR1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT)
  • [PGLU1]APELIN (24-36), HUMAN, BOVINE
  • PGLU-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE
  • [Pyr1]-Apelin-13,XRPRLSHKGPMPF,[pGlu1]-Apelin-13, >98%
  • [pGlu1]-Apelin-13
  • L-Phenylalanine, 5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-
  • PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH USP/EP/BP
  • 3-Dimethyluric acid
  • (Pyr?)-Apelin-13 (human, bovine, mouse, rat) acetate salt
  • [Pyr1]-Apelin-13 trifluoroacetate salt
  • {Glp}-RPRLSHKGPMPF
  • 217082-60-5
  • C69H108N22O16S
  • peptide