ChemicalBook > CAS DataBase List > NSC232003

NSC232003

Product Name
NSC232003
CAS No.
1905453-18-0
Chemical Name
NSC232003
Synonyms
NSC232003;5-(1-(Hydroxyamino)ethylidene)pyrimidine-2,4(3H,5H)-dione;2,4(3H,5H)-Pyrimidinedione, 5-[1-(hydroxyamino)ethylidene]-;E2 conjugating enzyme,Ubiquitin activating enzyme,Inhibitor,NSC 232003,inhibit,E1 activating enzyme,Ubiquitin conjugating enzyme,E1/E2/E3 Enzyme,E3 ligating enzyme,NSC232003,Ubiquitin ligase,NSC-232003
CBNumber
CB43356168
Molecular Formula
C6H7N3O3
Formula Weight
169.14
MOL File
1905453-18-0.mol
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NSC232003 Property

Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Water : 17 mg/mL (100.51 mM);DMSO : < 1 mg/mL (insoluble or slightly soluble)
form 
Solid
pka
9.32±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7657
Product name
NSC232003
Purity
98.66%
Packaging
1mg
Price
$180
Updated
2021/12/16
ChemScene
Product number
CS-7657
Product name
NSC232003
Purity
98.66%
Packaging
5mg
Price
$540
Updated
2021/12/16
ChemScene
Product number
CS-7657
Product name
NSC232003
Purity
98.66%
Packaging
10mg
Price
$900
Updated
2021/12/16
ChemScene
Product number
CS-7657
Product name
NSC232003
Purity
98.66%
Packaging
50mg
Price
$2700
Updated
2021/12/16
ChemScene
Product number
CS-7657
Product name
NSC232003
Purity
98.66%
Packaging
100mg
Price
$4020
Updated
2021/12/16
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NSC232003 Chemical Properties,Usage,Production

Uses

NSC232003 is a highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level.

References

[1] Myrianthopoulos V, et al. Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation. Eur J Med Chem. 2016 May 23;114:390-6. DOI:10.1016/j.ejmech.2016.02.043

NSC232003 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC232003 Suppliers

MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71615
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9572
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7998
Advantage
62
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29661
Advantage
68
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
Advantage
58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32469
Advantage
58
Shanghai Zeye Biotechnology Co., Ltd.
Tel
021-02161998551 13122364865
Email
sale1@shzysw.net
Country
China
ProdList
9779
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58

1905453-18-0, NSC232003Related Search:

D18

  • NSC232003
  • 5-(1-(Hydroxyamino)ethylidene)pyrimidine-2,4(3H,5H)-dione
  • E2 conjugating enzyme,Ubiquitin activating enzyme,Inhibitor,NSC 232003,inhibit,E1 activating enzyme,Ubiquitin conjugating enzyme,E1/E2/E3 Enzyme,E3 ligating enzyme,NSC232003,Ubiquitin ligase,NSC-232003
  • 2,4(3H,5H)-Pyrimidinedione, 5-[1-(hydroxyamino)ethylidene]-
  • 1905453-18-0