{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

Product Name: {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester
CAS No.: 1807521-06-7
Chemical Name: {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester
Synonyms: Ph-Bis(C1-N-(C2-NH-Boc)2);{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester;tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate;10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester
CBNumber: CB43363807
Molecular Formula: C36H64N6O8
Formula Weight: 708.93
MOL File: 1807521-06-7.mol

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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Property

Boiling point:: 775.5±60.0 °C(Predicted)
Density: 1.093±0.06 g/cm3(Predicted)
pka: 11.79±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22351
Product name: {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Purity: 96%
Packaging: 100mg
Price: $350
Updated: 2021/12/16

Apolloscientific

Product number: OR323158
Product name: {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Packaging: 100mg
Price: $731
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4656-1-3H
Product name: tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate
Packaging: 100mg
Price: $807
Updated: 2021/12/16

BroadPharm

Product number: BP-22351
Product name: {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Purity: 96%
Packaging: 500mg
Price: $980
Updated: 2021/12/16

BroadPharm

Product number: BP-22351
Product name: {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Purity: 96%
Packaging: 1g
Price: $1470
Updated: 2021/12/16

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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Chemical Properties,Usage,Production

Biological Activity

Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Preparation Products And Raw materials

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Preparation Products

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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Suppliers

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Apollo Scientific Ltd.

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1807521-06-7, {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl esterRelated Search:

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate

Ph-Bis(C1-N-(C2-NH-Boc)2)

10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester

1807521-06-7