ChemicalBook > CAS DataBase List > t-Boc-N-Amido-PEG2-Ms
t-Boc-N-Amido-PEG2-Ms
- Product Name
- t-Boc-N-Amido-PEG2-Ms
- CAS No.
- 302331-20-0
- Chemical Name
- t-Boc-N-Amido-PEG2-Ms
- Synonyms
- Boc-N-PEG2-Ms;Boc-NH-PEG2-Ms;Boc-N-PEG2-Oms;t-Boc-N-Amido-PEG2-Ms;2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl methanesulfonate;5,8-Dioxa-9-thia-2-azadecanoic acid, 1,1-dimethylethyl ester, 9,9-dioxide
- CBNumber
- CB43364011
- Molecular Formula
- C10H21NO6S
- Formula Weight
- 283.34
- MOL File
- 302331-20-0.mol
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t-Boc-N-Amido-PEG2-Ms Property
- Boiling point:
- 439.8±30.0 °C(Predicted)
- Density
- 1.182±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- form
- Liquid
- pka
- 12.18±0.46(Predicted)
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-23290
- Product name
- t-Boc-N-Amido-PEG2-Ms
- Purity
- 98%
- Packaging
- 1g
- Price
- $480
- Updated
- 2021/12/16
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t-Boc-N-Amido-PEG2-Ms Chemical Properties,Usage,Production
Description
t-Boc-N-Amido-PEG2-Ms is a PEG linker that contains a Boc protecting group and a mesyl group. The t-Boc group can be removed under acidic conditions. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains increase the water solubility properties of the compound.
Uses
Boc-N-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-Amido-PEG2-Ms Preparation Products And Raw materials
Raw materials
Preparation Products
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t-Boc-N-Amido-PEG2-Ms Suppliers
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- 0514-86654616 15366892466
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- China
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- psaitong@jm-bio.com
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View Lastest Price from t-Boc-N-Amido-PEG2-Ms manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Boc-NH-PEG2-Ms 302331-20-0
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25
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