t-Boc-N-Amido-PEG2-Ms
- Product Name
- t-Boc-N-Amido-PEG2-Ms
- CAS No.
- 302331-20-0
- Chemical Name
- t-Boc-N-Amido-PEG2-Ms
- Synonyms
- Boc-N-PEG2-Ms;Boc-NH-PEG2-Ms;Boc-N-PEG2-Oms;t-Boc-N-Amido-PEG2-Ms;2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl methanesulfonate;5,8-Dioxa-9-thia-2-azadecanoic acid, 1,1-dimethylethyl ester, 9,9-dioxide
- CBNumber
- CB43364011
- Molecular Formula
- C10H21NO6S
- Formula Weight
- 283.34
- MOL File
- 302331-20-0.mol
t-Boc-N-Amido-PEG2-Ms Property
- Boiling point:
- 439.8±30.0 °C(Predicted)
- Density
- 1.182±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- form
- Liquid
- pka
- 12.18±0.46(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- BP-23290
- Product name
- t-Boc-N-Amido-PEG2-Ms
- Purity
- 98%
- Packaging
- 1g
- Price
- $480
- Updated
- 2021/12/16
t-Boc-N-Amido-PEG2-Ms Chemical Properties,Usage,Production
Description
t-Boc-N-Amido-PEG2-Ms is a PEG linker that contains a Boc protecting group and a mesyl group. The t-Boc group can be removed under acidic conditions. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains increase the water solubility properties of the compound.
Uses
Boc-N-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-Amido-PEG2-Ms Preparation Products And Raw materials
Raw materials
Preparation Products
t-Boc-N-Amido-PEG2-Ms Suppliers
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View Lastest Price from t-Boc-N-Amido-PEG2-Ms manufacturers
- Product
- Boc-NH-PEG2-Ms 302331-20-0
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25