ChemicalBook > CAS DataBase List > Amino-PEG7-acid

Amino-PEG7-acid

Product Name
Amino-PEG7-acid
CAS No.
2376111-92-9
Chemical Name
Amino-PEG7-acid
Synonyms
Amino-PEG7-acid;Amino-PEG7-propionic acid;Inhibitor,PROTAC Linkers,inhibit,Amino PEG7 acid,AminoPEG7acid,Amino-PEG-7-acid
CBNumber
CB43369445
Molecular Formula
C17H35NO9
Formula Weight
397.47
MOL File
2376111-92-9.mol
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Amino-PEG7-acid Property

Boiling point:
514.7±50.0 °C(Predicted)
Density 
1.129±0.06 g/cm3(Predicted)
storage temp. 
-20°C, sealed storage, away from moisture and light
pka
4.28±0.10(Predicted)
form 
Oil
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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Amino-PEG7-acid Chemical Properties,Usage,Production

Uses

Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Amino-PEG7-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Amino-PEG7-acid Suppliers

Borenpharm Co., Ltd
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View Lastest Price from Amino-PEG7-acid manufacturers

LAURENT
Product
NH2-PEG7-CH2CH2COOH 2376111-92-9
Price
US $221.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-17
Xian confluore Biological Technology Co., Ltd.
Product
Amino-PEG7-COOH 2376111-92-9
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-22