ChemicalBook > CAS DataBase List > Neoseptin 3

Neoseptin 3

Product Name
Neoseptin 3
CAS No.
1622863-21-1
Chemical Name
Neoseptin 3
Synonyms
Neoseptin 3;Neoseptin-3 >=98% (HPLC);tert-butyl (2S)-2-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-4-phenylbutanoate;Benzenebutanoic acid, α-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-, 1,1-dimethylethyl ester, (αS)-
CBNumber
CB43386501
Molecular Formula
C29H34N2O4
Formula Weight
474.6
MOL File
1622863-21-1.mol
More
Less

Neoseptin 3 Property

Boiling point:
663.9±55.0 °C(Predicted)
Density 
1.174±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: ≥ 100 mg/mL (210.71 mM)
form 
Solid
pka
10.05±0.15(Predicted)
color 
White to off-white
optical activity
[α]/D 37 to 45°, c =0.1 in chloroform
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-0035376
Product name
Neoseptin3
Purity
>98.0%
Packaging
5mg
Price
$190
Updated
2021/12/16
ChemScene
Product number
CS-0035376
Product name
Neoseptin3
Purity
>98.0%
Packaging
10mg
Price
$340
Updated
2021/12/16
ChemScene
Product number
CS-0035376
Product name
Neoseptin3
Purity
>98.0%
Packaging
25mg
Price
$720
Updated
2021/12/16
More
Less

Neoseptin 3 Chemical Properties,Usage,Production

Biological Activity

Neoseptin-3 is a highly efficacious and specific agonist of the mouse TLR4 (mTLR4)/myeloid differentiation factor 2 (MD-2) complex. Neoseptin-3 binds to MD2, changes the conformation of MD-2 and facilitates active TLR4/MD-2 dimer formation. Neoseptin-3 exhibits no structural similarity to lipid A. ', 'Neoseptin-3 stimulates the activity of mouse TLR4 (mTLR4)/myeloid differentiation factor 2 (mTLR) independently of CD14 (cluster of differentiation 14). This activated mTLR4/ mTLR promotes canonical myeloid differentiation primary response gene 88 (MyD88) and toll-interleukin(IL) 1 receptor (TIR) domain-containing adaptor inducing interferon (IFN)-β (TRIF)-dependent signaling. In addition, neoseptin-3 also stimulates tumor necrosis factor α (TNF-α), IL-6 and IFNβ production in a dose-dependent manner.

Neoseptin 3 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Neoseptin 3 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

1622863-21-1, Neoseptin 3Related Search:


  • Neoseptin 3
  • tert-butyl (2S)-2-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-4-phenylbutanoate
  • Benzenebutanoic acid, α-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-, 1,1-dimethylethyl ester, (αS)-
  • Neoseptin-3 >=98% (HPLC)
  • 1622863-21-1