BEAUVERICIN

Product Name: BEAUVERICIN
CAS No.: 26048-05-5
Chemical Name: BEAUVERICIN
Synonyms: nivea;bovein;bassiana;beauverin;Beauveria;BEAUVERICIN;BEAUVERFICIN;Beauveria sp.;Beauvericin 97%;13C45-Beauvericin
CBNumber: CB4345714
Molecular Formula: C45H57N3O9
Formula Weight: 783.95
MOL File: 26048-05-5.mol

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BEAUVERICIN Property

Melting point:: 93-94℃
Boiling point:: 975.6±65.0 °C(Predicted)
Density: 1.126±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in DMSO (30 mg/ml)
pka: -1.02±0.70(Predicted)
form: Solid
color: White
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey: GYSCAQFHASJXRS-ABKJGVMTSA-N

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Safety

WGK Germany: 3
HS Code: 29419090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B7510
Product name: Beauvericin
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $218
Updated: 2024/03/01

Sigma-Aldrich

Product number: 37012
Product name: Beauvericin
Purity: VETRANAL?, analytical standard
Packaging: 100μg
Price: $895
Updated: 2022/05/15

Cayman Chemical

Product number: 11426
Product name: Beauvericin
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 11426
Product name: Beauvericin
Purity: ≥95%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 11426
Product name: Beauvericin
Purity: ≥95%
Packaging: 10mg
Price: $261
Updated: 2024/03/01

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BEAUVERICIN Chemical Properties,Usage,Production

Description

Beauvericin (CAS 26048-05-5) induces apoptosis in A549 cancer cells.1 Disrupts mitochondrial volume regulation.2 Antifungal activity acting via inhibition of both multidrug efflux and TORC1 kinase.3 Crosses the blood-brain barrier in mice.4 Inhibits HIV-1 integrase.5

Chemical Properties

White powder

Uses

Beauvericin is a cyclic depsipeptide isolated from several fungal genera, notably Beauveria and Fusarium, first reported in 1969. Beauvericin exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities. At the molecular level, beauvericin exhibits ionophoric properties, and inhibits acyl-CoA:cholesterol acyltransferase activity. Beauvericin induces apoptosis by elevating intracellular calcium levels.

Uses

Toxic depsipeptide with antibiotic and insecticidal effects.Beauvericin is a toxic depsipeptide with antibiotic and insecticidal effects.

Definition

ChEBI: A trimeric cyclodepsipeptide composed from alternating methylphenylalanyl and hydroxyvaleryl residues.

References

1) Lu et al. (2016), Beauvericin-induced cell apoptosis through the mitogen-activated protein kinase pathway in human nonsmall cell lung cancer A549 cells.; J. Toxicol. Sci., 41 429 2) Tonshin et al. (2010), The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis.; Toxicology, 276 49 3) Shekhar-Guturja et al. (2016), Dual action antifungal small molecule modulates multidrug efflux and TOR signaling; Nat. Chem. Biol., 12 867 4) Taevernier et al. (2016), Blood-brain barrier transport kinetics of the cyclic depsipeptide mycotoxins beauvericin and enniatins; Toxicol. Lett., 258 175 5) Shin et al. (2009), Beauvericin and enniatins H,I and MK1688 are new potent inhibitors of human immunodeficiency virus type-1 integrase; J. Antibiot. (Tokyo), 62 687

BEAUVERICIN Preparation Products And Raw materials

Raw materials

Filler Potassium Phosphate Monobasic

Preparation Products

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BEAUVERICIN Suppliers

Canada 1 China 151 Germany 1 India 1 Switzerland 1 United Kingdom 6 United States 18 USA 1 Global 180

Wuhan Chujiang Haoyu Chemical Technology Development Co., Ltd.

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WUHAN GEEYESCHEM CHEMICAL CO., LTD.

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Wuhan Jiyesheng Chemical Co. , Ltd.

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Qingdao IniKem BioPharmaTech Co.,Ltd

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J & K SCIENTIFIC LTD.

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Jinxiang Chemical (Danyang) Products Co., Ltd.

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Chemsky (shanghai) International Co.,Ltd

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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View Lastest Price from BEAUVERICIN manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: BEAUVERICIN 26048-05-5
Price: US $20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-24

Hebei Zhuanglai Chemical Trading Co Ltd

Product: BEAUVERICIN 26048-05-5
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-11-29

Hebei Shengyang Water Conservancy Engineering Co., Ltd.

Product: BEAUVERICIN 26048-05-5
Price: US $18.00/kg
Min. Order: 1kg
Purity: 99.9
Supply Ability: 5000
Release date: 2024-05-10

26048-05-5, BEAUVERICINRelated Search:

Emamectin Bis(2-dimethylaminoethyl) ether 2-((2-(2-(DIMETHYLAMINO)ETHOXY)ETHYL) METHYLAMINO)ETHANOL, 97 1,5-DIAMINO-3-OXAPENTANE GLYCINE N-PROPYL ESTER HYDROCHLORIDE N,N-Dimethylglycine ethyl ester Propanamide, 2-hydroxy-N,N-dimethyl- (9CI) N-(2-HYDROXYETHYL)LACTAMIDE N,N-DIMETHYL-L-PHENYLALANINE BEAUVERICIN 1,5-BIS(METHYLAMINO)-3-OXAPENTANE, 98 AC-PHE-OET N,N-DIMETHYL-2-METHOXYACETAMIDE AC-PHE-OME ethyl 2-(propylamino)acetate beauvericin synthetase ethyl 2-(butylamino)acetate N,N-DI(2-METHOXY)ETHYLAMMONIUM ACETATE

Beauvericin, froM Beauveria bassiana

CYCLO-[D-ALPHA-HYDROXYISOVALERYL-L-N-METHYLPHENYLALANYL]3

CYCLO(-D-ALPHA-HYDROXYISOVALERYL-N-ME-PHE)3

BEAUVERICIN

cyclo(d-α-hydroxyisovaleryl-l-n-methyl-phe)3

BEAUVERFICIN

beauverin

beauverin bassiaua vuillemin

bovein

Beauvericin 97%

Cyclo[(2R)-2-hydroxy-3-Methylbutanoyl-N-Methyl-L-phenylalanyl-(2R)-2-hydroxy-3-Methylbutanoyl-N-Methyl-L-phenylalanyl-(2R)-2-hydroxy-3-Methylbutanoyl-N-Methyl-L-phenylalanyl]

Cyclo(-D-a-hydroxyisovaleryl-N-Me-Phe)3

Beauvericin, 99%, from Beauveria bassiana

N-Methylcyclo(L-Phe-D-Hmb-N-methyl-L-Phe-D-Hmb-N-methyl-L-Phe-D-Hmb-)

Beauveria

Beauveria Vuillemin

Beauveria Vuillemin sp

nivea

bassiana

Beauveria sp.

Beauveria bassiana (Bals.-Criv.) Vuill.

Beauveria bassiana (Balsamo) Vuillemin

Beauveria bassiana AS 3.4271

Beauveria brongiartii

BEAUVERICIN USP/EP/BP

13C45-Beauvericin

(3S,6R,9S,12R,15S,18R)-3,9,15-Tribenzyl-6,12,18-triisopropyl-4,10,16-trimethyl-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexaone

(3S,6R,9S,12R,15S,18R)-3,9,15-tribenzyl-4,10,16-trimethyl-6,12,18-tris(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

Beauvericin in dried down

Beauvericin 100 μg/ml Acetonitrile

Beauvericin in Acetonitrile

Beauvericin, 10 mM in DMSO

26048-05-5

63428-80-0

C45H57N3O9

C44H57N3O8

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

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