HUMAN IL-21
Epitope Sensitivity Immunogen Detection Epitope Reactivity Immunogen Epitope Source_Species Conjugations Immunogen Usage Tag Epitope Reactivity Reactivity Specificity Epitope Immunogen Measurement Format Format Specificity Format Immunogen Immunogen Epitope Specificity Conjugations Epitope Host Format Format Specificity Reactivity Conjugations Specificity Usage Detection_Range Format Clonality Reactivity Conjugations Specificity Epitope Reactivity Conjugations Specificity Specificity Specificity Reactivity Conjugations Expression_System Format Immunogen- Product Name
- HUMAN IL-21
- Chemical Name
- HUMAN IL-21
- Synonyms
- Za11;IL-21;CVID11;IL-D110;UNQ3099;zcyto18;PRO10096;TIFIL-23;HUMAN IL-21;Cytokine Zcyto18
- CBNumber
- CB4347859
- Formula Weight
- 0
- MOL File
- Mol file
HUMAN IL-21 Property
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- mouse
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
N-Bromosuccinimide Price
- Product number
- 356692
- Product name
- IL-21
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- 472375
- Product name
- IL-21
- Packaging
- 96Tests
- Price
- $731
- Updated
- 2021/12/16
- Product number
- 472376
- Product name
- IL-21
- Packaging
- 96Tests
- Price
- $751
- Updated
- 2021/12/16
- Product number
- 472374
- Product name
- IL-21
- Packaging
- 96Tests
- Price
- $751
- Updated
- 2021/12/16
- Product number
- orb602687
- Product name
- IL21
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
HUMAN IL-21 Chemical Properties,Usage,Production
Epitope
aa2-224
Sensitivity
0.39 ng/mL
Immunogen
Synthetic peptide from C-Terminus of human CSNK1G2 (P78368, NP_001310). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Opossum (100%); Mouse, Rat, Elephant, Panda, Dog, Bovine, Pig, Platypus, Xenopus, Zebrafish (92%); Rabbit, Guinea pig, Salmon (85%); Orangutan, Bat, Horse (84%).
Detection
Colorimetric
Epitope
aa204-231
Reactivity
Duck
Immunogen
Recombinant human Dual oxidase 1 protein (1312-1551AA)
Epitope
aa109-138
Source_Species
E. coli
Conjugations
Biotin
Immunogen
Alpha-2-Macroglobulin.
Usage
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
Tag
GST, N-terminus ; His, C-terminus
Epitope
C-Terminus
Reactivity
Pig
Reactivity
Mouse
Specificity
The antibody is a rabbit polyclonal antibody raised against FKBP3.
Epitope
aa56-83
Immunogen
Recombinant CSNK1d (Met1-Arg415)
Measurement
Format
Unconjugated, Unmodified
Format
Horseradish Peroxidase, Azide-free
Specificity
Human CSNK1G2
Format
FITC, Unmodified
Immunogen
DTW domain containing 2
Immunogen
Recombinant FKBP3 (Ala2-Asp224) expressed in E. coli.
Epitope
aa144-173
Specificity
Duck Alpha-2-Macroglobulin / A2M
Conjugations
Cy3
Epitope
aa35-84
Host
Rabbit
Format
Cy3, Unmodified
Format
Horseradish Peroxidase, Unmodified
Specificity
The antibody is a rabbit polyclonal antibody raised against CSNK1d.
Reactivity
Human; Chimpanzee; Gibbon; Monkey
Conjugations
HRP
Specificity
Human DTX1
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Detection_Range
0.78 - 50 ng/ml
Format
Allophycocyanin, Unmodified
Clonality
Polyclonal
Reactivity
Human; Mouse
Conjugations
FITC
Specificity
This DTWD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the Central region of human DTWD1.
Epitope
aa1-415
Reactivity
Mouse; Human
Conjugations
Unconjugated
Specificity
This DTX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human DTX4.
Specificity
This Mouse Csnk1d antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-231 amino acids from the Central region of mouse Csnk1d.
Specificity
This DTWD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human DTWD2.
Reactivity
Human
Conjugations
Allophycocyanin
Expression_System
E. coli
Format
Biotin, Unmodified
Immunogen
Synthetic peptide located between aa35-84 of human DTX1 (Q86Y01, NP_004407). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum (100%); Stickleback (85%).
Species
Human
Description
DTWD2 antibody is an unconjugated rabbit polyclonal antibody to human DTWD2. Validated for ELISA and IP.
Description
DTX4 antibody is an APC-conjugated rabbit polyclonal antibody to human DTX4 (aa56-83). Validated for ELISA and WB.
Description
DTWD1 antibody is an HRP-conjugated rabbit polyclonal antibody to human DTWD1 (aa144-173). Validated for ELISA and WB.
Description
CSNK1D antibody is an unconjugated rabbit polyclonal antibody to mouse CSNK1D (aa204-231). Validated for WB.
Description
CKI-Gamma 2 antibody is an FITC-conjugated rabbit polyclonal antibody to CKI-Gamma 2 (CSNK1G2) (C-Terminus) from human. It is reactive with human, chimpanzee, gibbon and other species. Validated for IHC and WB.
Description
DUOX antibody is an unconjugated rabbit polyclonal antibody to human DUOX. Validated for ELISA and IHC.
Description
DTX4 antibody is an unconjugated rabbit polyclonal antibody to human DTX4 (aa56-83). Validated for Flow, IHC and WB.
Description
FKBP3 antibody is a Cy3-conjugated rabbit polyclonal antibody to FKBP3 (FKBP25) (aa2-224) from mouse. It is reactive with human and mouse. Validated for WB.
Description
Deltex antibody is an unconjugated rabbit polyclonal antibody to human Deltex (DTX1) (aa35-84). Validated for WB.
Description
DTWD1 antibody is an APC-conjugated rabbit polyclonal antibody to human DTWD1 (aa144-173). Validated for ELISA and WB.
Description
DTWD2 antibody is an HRP-conjugated rabbit polyclonal antibody to DTWD2 (aa109-138) from human. It is reactive with human and mouse. Validated for ELISA and WB.
Description
Alpha-2-Macroglobulin antibody is a biotin-conjugated rabbit polyclonal antibody to duck Alpha-2-Macroglobulin (A2M). Validated for WB.
Description
DTWD1 antibody is a biotin-conjugated rabbit polyclonal antibody to human DTWD1 (aa144-173). Validated for ELISA and WB.
Description
FKBP3 antibody is an HRP-conjugated rabbit polyclonal antibody to FKBP3 (FKBP25) (aa2-224) from mouse. It is reactive with human and mouse. Validated for WB.
Description
CSNK1D antibody is an FITC-conjugated rabbit polyclonal antibody to human CSNK1D (aa1-415). Validated for WB.
Application
IHC; IHC-P; ELISA
Application
IHC; IHC-P; WB; FC
Application
WB; ELISA
Application
IP; ELISA
Application
IHC; IHC-P; WB
Application
WB
Biological Activity
IL-21 (interleukin-21) belongs to the IL-2 cytokine family. It is secreted by CD4+ T, natural killer (NK) and Th17 cells. IL-21 associates with IL-21 receptor and participates in B-cell proliferation, differentiation as well as apoptosis. It also promotes the cytotoxic activity of CD8+ T cells and natural killer cells.IL-21 plays a crucial role in the differentiation of follicular helper T cells. It also exhibits antitumor activity. It is also involved in the activation of JAK-ST at (Janus kinase - signal transducer and activator of transcription), PI3K (phosphatidylinositol 3-kinase) and MAPK (mitogen activated protein kinase) pathways.', 'IL-21 and its receptor have important roles in T and B cell proliferation and natural killer cell maturation. Human and mouse IL-21 share 57% amino acid identity.
target
CSNK1G2
target
CSNK1D
target
DTX4
target
Duck A2M
target
DTWD2
target
DTWD1
target
DTX1
target
DUOX
target
DUOX2
target
FKBP25
HUMAN IL-21 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN IL-21 Suppliers
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