ChemicalBook > CAS DataBase List > 1-Lauryl-2-pyrrolidone

1-Lauryl-2-pyrrolidone

Product Name
1-Lauryl-2-pyrrolidone
CAS No.
2687-96-9
Chemical Name
1-Lauryl-2-pyrrolidone
Synonyms
1-DODECYL-2-PYRROLIDINONE;LAURYL PYRROLIDONE;N-DODECYL-2-PYRROLIDONE;Creastar Au-Ex;Sulfadone LP-300;N-Laurylpyrrolidone;N-DODECYLPYRROLIDONE;1-dodecylpyrrolidone;1-Lauryl-2-pyrrolido;1-Lauryl-2-pyrrolidone
CBNumber
CB4358536
Molecular Formula
C16H31NO
Formula Weight
253.42
MOL File
2687-96-9.mol
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1-Lauryl-2-pyrrolidone Property

Melting point:
4°C
Boiling point:
202-205 °C11 mm Hg(lit.)
Density 
0.89 g/mL at 25 °C(lit.)
vapor pressure 
0.002Pa at 25℃
refractive index 
n20/D 1.466(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
form 
viscous liquid
pka
-0.43±0.20(Predicted)
Appearance
Colorless to light yellow Liquid
Water Solubility 
51.7mg/L at 20℃
InChIKey
NJPQAIBZIHNJDO-UHFFFAOYSA-N
LogP
4.03 at 21℃
CAS DataBase Reference
2687-96-9(CAS DataBase Reference)
EPA Substance Registry System
N-Lauryl-2-pyrrolidone (2687-96-9)
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Safety

Hazard Codes 
C,N
Risk Statements 
34-43-50/53
Safety Statements 
26-36/37/39-45-60-61
RIDADR 
UN 3267 8/PG 3
WGK Germany 
2
RTECS 
UY5768000
HazardClass 
8
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
335673
Product name
1-Dodecyl-2-pyrrolidinone
Purity
99%
Packaging
250ml
Price
$79.54
Updated
2025/07/31
TRC
Product number
D494573
Product name
1-Dodecyl-2-pyrrolidinone
Packaging
2mL
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
099851
Product name
1-Dodecylpyrrolidin-2-one
Purity
95+%
Packaging
250mg
Price
$167
Updated
2021/12/16
Matrix Scientific
Product number
099851
Product name
1-Dodecylpyrrolidin-2-one
Purity
95+%
Packaging
1g
Price
$370
Updated
2021/12/16
Matrix Scientific
Product number
099851
Product name
1-Dodecylpyrrolidin-2-one
Purity
95+%
Packaging
5g
Price
$1040
Updated
2021/12/16
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1-Lauryl-2-pyrrolidone Chemical Properties,Usage,Production

Chemical Properties

Colorless transparent liquid

Uses

1-Dodecyl-2-pyrrolidinone was used in the preparation of few-layered flakes of molybdenum disulfide (MoS2) via liquid phase exfoliation of bulk MoS2 powder.

Definition

ChEBI: 1-dodecylpyrrolidin-2-one is pyrrolidin-2-one substituted at nitrogen by an n-dodecyl group. It has a role as an epitope.

General Description

1-Dodecyl-2-pyrrolidinone is an N-alkyl lactam and its reduction with LiH3BNMe2 to the corresponding amine has been reported. It is a potential melatonin-specific chemical penetration enhancer.

Flammability and Explosibility

Non flammable

Synthesis

616-45-5

143-15-7

2687-96-9

Step A: Tetrabutylammonium bromide (950 mg, 3 mmol, 0.05 eq.) and powdered potassium hydroxide (23.1 g, 411 mmol, 7 eq.) were sequentially added to a toluene (60 mL) solution of 2-pyrrolidone (5.00 g, 58.8 mmol) under stirring conditions. Subsequently, a toluene solution of bromododecane (18.5 mL, 76.4 mmol, 1.3 eq.) was added to the mixture. The reaction mixture was heated to 50 °C and stirred at this temperature overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) using a solvent mixture of ethyl acetate and cyclohexane (4:1, v/v) as the unfolding agent and phosphomolybdic acid as the color developer until the complete disappearance of 2-pyrrolidone. After completion of the reaction, the mixture was cooled to room temperature, 60 mL of water was added and stirring was continued for 15 min. The aqueous and organic phases were separated and the aqueous phase was extracted once with diethyl ether (60 mL). The organic phase was combined, dried with anhydrous sodium sulfate, filtered and concentrated. The product was purified by vacuum distillation (146 °C, 0.5 mbar) to afford N-dodecylpyrrolidin-2-one in 80% yield. The structure of the product was characterized by 1H NMR and 13C NMR: 1H NMR (400 MHz, CDCl3) δ (ppm): 0.88 (t, 3H, J = 7.0 Hz, CH3); 1.25-1.31 (m, 18H, CH2); 1.47-1.54 (m, 2H, Alk-CH2-CH2-N); 1.97- 2.05 (m, 2H, CO-CH2-CH2-CH2-N); 2.38 (t, 2H, J = 8.0 Hz, CO-CH2-CH2-CH2-N); 3.26 (t, 2H, J = 7.5 Hz, Alk-CH2-CH2-N); 3.37 (t, 2H, J = 7.0 Hz, CO-CH2-CH2-CH2- N).13C NMR (100 MHz, CDCl3) δ (ppm): 14.3 (CH3); 18.1 (CO-CH2-CH2-CH2-N); 22.9; 27.0 (CH2alk); 27.5 (Alk-CH2-CH2-N); 29.5; 29.7; 29.8; 29.9 (CH2alk); 31.3 (CO-CH2-CH2-CH2-N); 32.1 (CH2alk); 42.7 (Alk-CH2-CH2-N); 47.2 (CO-CH2-CH2-CH2-N); 174.9 (CO).

References

[1] Patent: US2015/133688, 2015, A1. Location in patent: Page/Page column

1-Lauryl-2-pyrrolidone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Lauryl-2-pyrrolidone Suppliers

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View Lastest Price from 1-Lauryl-2-pyrrolidone manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
1-Lauryl-2-pyrrolidone 2687-96-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 mt
Release date
2024-11-11
Qingdao RENAS Polymer Material Co., Ltd.
Product
1-dodecyl-2-pyrrolidinone 2687-96-9
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2025-03-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
Lauryl Pyrrolidone 2687-96-9
Price
US $8.70/KG
Min. Order
10KG
Purity
99.5% min
Supply Ability
10000kg
Release date
2024-08-21

2687-96-9, 1-Lauryl-2-pyrrolidoneRelated Search:

N,N-Dimethyldodecylamine 1-Dodecanol DODECYLBENZENE 4-DODECYLPHENOL MIXTURE OF ISOMERS N-Vinyl-2-pyrrolidone 2-Pyrrolidinone CALCIUM DODECYLBENZENE SULFONATE Ammonium lauryl sulfate Polyvinylpyrrolidone 1,2-EPOXYTETRADECANE Dodecylbenzenesulphonic acid SODIUM LAURYL DIETHYLENEDIAMINOGLYCINATE Polyquaternium-11 1-Propylpyrrolidin-2-one 1-Ethyl-2-pyrrolidone METHYL-2-PYRROLIDONE N-Octyl pyrrolidone 1-Butylpyrrolidin-2-one

  • 1-dodecyl-2-pyrrolidinon
  • 1-Dodecyl-2-pyrrolidone
  • N-DODECYLPYRROLIDONE
  • N-DODECYL-2-PYRROLIDONE
  • 1-DODECYL-2-PYRROLIDINONE
  • 1-Lauryl-2-pyrrolidone
  • LAURYL PYRROLIDONE
  • N-Laurylpyrrolidone
  • 2-Pyrrolidinone, 1-dodecyl-
  • 1-dodecylpyrrolidone
  • N-TETRADECYL-2-PYRROLIDONE
  • n-dodecylpyrrolidinone
  • N-DODECYLPYRROLIDONE OR 1-DODECYLPYRROLIDONE
  • N-Lauryl-2-pyrrolidone
  • N-dodecy1-2-prrolidone
  • 1-Dodecylpyrrolidin-2-one
  • Sulfadone LP-300
  • 1-Lauryl-2-pyrrolido
  • N-(n-dodecyl) Pyrrolidinone
  • N-Dodecyl-2-Pyrrolidinone
  • Creastar Au-Ex
  • 2687-96-9 1-Lauryl-2-pyrrolidone
  • 2687-96-9
  • 2687-96-4
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrrolidines