Synthesis
ChemicalBook > CAS DataBase List > N-Octyl pyrrolidone

N-Octyl pyrrolidone

Synthesis
Product Name
N-Octyl pyrrolidone
CAS No.
2687-94-7
Chemical Name
N-Octyl pyrrolidone
Synonyms
N-OCTYL-2-PYRROLIDONE;1-N-OCTYL-2-PYRROLIDONE;1-OCTYL-2-PYRROLIDONE;1-OCTYLPYRROLIDIN-2-ONE;1-octylpyrrolidine;N-OCTYL PYRROLIDONE;1-Octyl-2-pyrrolidon;n-octylpyrrolidinone;Methylglyoxal 78-98-8;1-octyl-2-pyrrolidinon
CBNumber
CB0388315
Molecular Formula
C12H23NO
Formula Weight
197.32
MOL File
2687-94-7.mol
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N-Octyl pyrrolidone Property

Melting point:
−25 °C(lit.)
Boiling point:
170-172 °C15 mm Hg(lit.)
Density 
0.92 g/mL at 25 °C(lit.)
vapor pressure 
0.03-0.08Pa at 20℃
refractive index 
n20/D 1.465(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
pka
-0.42±0.20(Predicted)
form 
clear liquid
color 
Colorless to Yellow
Specific Gravity
0.92
Water Solubility 
1.14-1.25g/L at 20℃
BRN 
1526318
InChIKey
WPPOGHDFAVQKLN-UHFFFAOYSA-N
LogP
4.15 at 20℃
CAS DataBase Reference
2687-94-7(CAS DataBase Reference)
EPA Substance Registry System
N-Octyl-2-pyrrolidone (2687-94-7)
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Safety

Hazard Codes 
C,N
Risk Statements 
34-51/53
Safety Statements 
23-26-36/37/39-45-1/2
RIDADR 
UN 3267 8/PG 2
WGK Germany 
2
RTECS 
UY5896000
HazardClass 
8
PackingGroup 
III
HS Code 
29339900
Toxicity
LD50 orl-rat: 2050 mg/kg FCTOD7 26,475,88
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
332186
Product name
1-Octyl-2-pyrrolidone
Purity
98%
Packaging
250ml
Price
$52.38
Updated
2024/03/01
Sigma-Aldrich
Product number
332186
Product name
1-Octyl-2-pyrrolidone
Purity
98%
Packaging
1l
Price
$243
Updated
2024/03/01
TCI Chemical
Product number
O0325
Product name
1-n-Octyl-2-pyrrolidone
Purity
>98.0%(GC)
Packaging
25mL
Price
$21
Updated
2024/03/01
TCI Chemical
Product number
O0325
Product name
1-n-Octyl-2-pyrrolidone
Purity
>98.0%(GC)
Packaging
500mL
Price
$117
Updated
2024/03/01
Chem-Impex
Product number
43841
Product name
1-n-Octyl-2-pyrrolidone,≥98%(GC)Hazmat
Purity
≥98%(GC)
Packaging
25ML
Price
$17.34
Updated
2021/12/16
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N-Octyl pyrrolidone Chemical Properties,Usage,Production

Synthesis

N-Octyl pyrrolidone was synthesized by 2-pyrrolidone and tetrabutylammonium bromide stirred with adding n-octane chloride for 10 h at 90 °C.

Chemical Properties

Colorless or slightly yellow clear liquid

Uses

N-Octyl pyrrolidone(NOP) is a highly efficient and selective solvent, which can be used in the recovery of organic raw materials, the refining of lubricating oils, and the solvent for polymers and polymerization reactions; It is also widely used in chemical synthesis reactions.

Definition

ChEBI: N-Octyl-2-pyrrolidone is a N-alkylpyrrolidine.

Synthesis Reference(s)

The Journal of Organic Chemistry, 57, p. 3328, 1992 DOI: 10.1021/jo00038a019

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 6378, 1994 DOI: 10.1021/jo00100a046

General Description

1-Octyl-2-pyrrolidone is a permeation enhancer and its effect in transport of steroidal permeants across hairless mouse skin was investigated via a parallel pathway skin model.

Flammability and Explosibility

Non flammable

Safety Profile

Moderately toxic by ingestion. Asevere skin and eye irritant. A corrosive. Combustibleliquid. When heated to decomposition it emits toxic fumesof NOx.

N-Octyl pyrrolidone Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Octyl pyrrolidone Suppliers

Hefei TNJ Chemical Industry Co.,Ltd.
Tel
551-65418679 15837135945
Fax
0551-65418697
Email
info@tnjchem.com
Country
China
ProdList
1889
Advantage
62
Shanghai Chengyu Biotechnology Co., Ltd.
Tel
021-51525055
Email
309639130@qq.com
Country
China
ProdList
42
Advantage
58
Wuhan penglei Biotechnology Co., Ltd
Tel
15871464247
Email
1545569349@QQ.COM
Country
China
ProdList
734
Advantage
58
Jiangsu Haolong Chemical Co., Ltd
Tel
0513-89083520 13328092525
Email
2363930984@qq.com
Country
China
ProdList
2056
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58
Zhongshan Dixin Chemical Co., Ltd
Tel
19129093253 19129093253
Email
2155195933@qq.com
Country
China
ProdList
1409
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
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View Lastest Price from N-Octyl pyrrolidone manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
N-Octyl Pyrrolidone 2687-94-7
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-25
HebeiShuoshengImportandExportco.,Ltd
Product
N-Octyl pyrrolidone 2687-94-7
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-07
Hebei Longbang Technology Co., Ltd
Product
N-Octyl pyrrolidone 2687-94-7
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-08

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