ChemicalBook > CAS DataBase List > Ethyl 4,4-difluoro-3-oxobutanoate

Ethyl 4,4-difluoro-3-oxobutanoate

Product Name
Ethyl 4,4-difluoro-3-oxobutanoate
CAS No.
352-24-9
Chemical Name
Ethyl 4,4-difluoro-3-oxobutanoate
Synonyms
ETHYL 4,4-DIFLUOROACETOACETATE;ETHYL 4,4-DIFLUORO-3-OXOBUTYRATE;AKOS B016254;AKOS MSC-0700;ART-CHEM-BB B016254;Ethyl 4,4-difluoroc;Difluoro aceto acetat;4-difluoro-3-oxobutanoate;4,4-Difluoroacylacidester;4,4-difluoro-3-oxobutanoate
CBNumber
CB4359962
Molecular Formula
C6H8F2O3
Formula Weight
166.12
MOL File
352-24-9.mol
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Ethyl 4,4-difluoro-3-oxobutanoate Property

Melting point:
-46°C(lit.)
Boiling point:
162 °C
Density 
1,61 g/cm3
refractive index 
1.407
Flash point:
68℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
clear liquid
pka
8.61±0.46(Predicted)
color 
Colorless to Almost colorless
InChI
InChI=1S/C6H8F2O3/c1-2-11-5(10)3-4(9)6(7)8/h6H,2-3H2,1H3
InChIKey
CBDPWKVOPADMJC-UHFFFAOYSA-N
SMILES
C(OCC)(=O)CC(=O)C(F)F
CAS DataBase Reference
352-24-9(CAS DataBase Reference)
EPA Substance Registry System
Ethyl 4,4-difluoroacetoacetate (352-24-9)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
10-36/37/38-36/38
Safety Statements 
26-36/37/39
RIDADR 
1993
WGK Germany 
3
Hazard Note 
Flammable
TSCA 
Yes
HazardClass 
3
HazardClass 
IRRITANT, FLAMMABLE
HS Code 
2918300090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1018
Product name
Ethyl 4,4-Difluoroacetoacetate
Purity
>96.0%(GC)
Packaging
5g
Price
$30
Updated
2021/12/16
TCI Chemical
Product number
E1018
Product name
Ethyl 4,4-Difluoroacetoacetate
Purity
>96.0%(GC)
Packaging
25g
Price
$81
Updated
2025/07/31
TRC
Product number
E678440
Product name
Ethyl 4,4-Difluoroacetoacetate
Packaging
10g
Price
$165
Updated
2021/12/16
TRC
Product number
E678440
Product name
Ethyl 4,4-Difluoroacetoacetate
Packaging
100g
Price
$745
Updated
2021/12/16
SynQuest Laboratories
Product number
2129-3-17
Product name
Ethyl 4,4-difluoro-3-oxobutyrate
Purity
97%
Packaging
5G
Price
$15
Updated
2021/12/16
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Ethyl 4,4-difluoro-3-oxobutanoate Chemical Properties,Usage,Production

Uses

Ethyl 4,4-Difluoroacetoacetate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.

Uses

Ethyl 4,4-difluoro-3-oxobutanoate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.

Ethyl 4,4-difluoro-3-oxobutanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4,4-difluoro-3-oxobutanoate Suppliers

Jinan Wanxingda Chemical Co., Ltd.
Tel
0531-88064106 18253116016
Fax
0531-88064109
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bruce@wxdchem.com
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China
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West fluorine technology co., ltd
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0531-85906692 15588812394
Fax
86-0531-85906692
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325912682@qq.com
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China
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15169176553; 15169176553
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644658103@qq.com
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China
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Shanghai Boyle Chemical Co., Ltd.
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021-50182298 021-50180596
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+86-21-57758967
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sales@boylechem.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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INTATRADE GmbH
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+49 3493/605464
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+49 3493/605470
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sales@intatrade.de
Country
Germany
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
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Ark Pharm, Inc.
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847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
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Beijing dtftchem Technology Co., Ltd.
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010-60275820 13031183356
Fax
010-60270825
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elainezt@sina.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
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View Lastest Price from Ethyl 4,4-difluoro-3-oxobutanoate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30
Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2025-04-01
Shaanxi Dideu New Materials Co. Ltd
Product
Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-25

352-24-9, Ethyl 4,4-difluoro-3-oxobutanoateRelated Search:


  • AKOS MSC-0700
  • AKOS B016254
  • ETHYL 4,4-DIFLUORO-3-OXOBUTYRATE
  • ETHYL 4,4-DIFLUOROACETOACETATE
  • ART-CHEM-BB B016254
  • Difluoro aceto acetat
  • Ethyl 4,4-difluoro-3-oxobutyrate 90%
  • Ethyl4,4-difluoro-3-oxobutyrate90%
  • 4,4-Difluoroacetoacetic acid ethyl ester
  • Ethyl 4,4-difluoro-3-oxobutanoate
  • 4,4-Difluoro-3-oxo butyric acid ethyl ester
  • Ethyl 4,4-difluoro-3-oxobutanoate 90%
  • Ethyl 4,4-difluoroc
  • 4,4-difluoro-3-oxobutanoate
  • 3-Oxo-4,4-difluorobutanoic acid ethyl ester
  • 3-Oxo-4,4-difluorobutyric acid ethyl ester
  • 4-difluoro-3-oxobutanoate
  • Butanoic acid,4,4-difluoro-3-oxo-, ethyl ester
  • Ethyl-4 4-difluoroacetoacetate- >98% -purity (Pack 100GM X 3 Nos)
  • Ethyl 4,4-difluoro-3-oxobutyrate, Ethyl 4,4-difluoro-3-oxobutanoate
  • Ethyl 4,4-difluorocetoacetate SynonyMs Ethyl 4,4-difluoro-3-oxobutanoate
  • 4,4-difluoro-ethyl acetoacetate
  • Ethyl 4,4-difluorocetoacetate
  • 4,4-Difluoro-3-oxobutanoic acid ethyl ester
  • Ethyl 4,4-difluoro-3-ketobutyrate
  • Ethyl4,4-Difluoroacetoacetate&gt
  • TIANFU CHEM---Ethyl 4,4-difluoro-3-oxobutanoate
  • Butanoic acid, 4,4-difluoro-3-oxo-, ethyl ester (9CI, ACI)
  • 4,4-difluoro-3-oxo-Butanoic acid ethyl ester (9CI ACI)
  • 4,4-Difluoroacylacidester
  • Ethyl4,4-difluoro-3-oxobutyrat
  • 352-24-9
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