ChemicalBook > CAS DataBase List > Ethyl 4,4-difluoro-3-oxobutanoate

Ethyl 4,4-difluoro-3-oxobutanoate

Product Name
Ethyl 4,4-difluoro-3-oxobutanoate
CAS No.
352-24-9
Chemical Name
Ethyl 4,4-difluoro-3-oxobutanoate
Synonyms
ETHYL 4,4-DIFLUOROACETOACETATE;ETHYL 4,4-DIFLUORO-3-OXOBUTYRATE;AKOS B016254;AKOS MSC-0700;ART-CHEM-BB B016254;Ethyl 4,4-difluoroc;Difluoro aceto acetat;4-difluoro-3-oxobutanoate;4,4-difluoro-3-oxobutanoate;Ethyl 4,4-difluorocetoacetate
CBNumber
CB4359962
Molecular Formula
C6H8F2O3
Formula Weight
166.12
MOL File
352-24-9.mol
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Ethyl 4,4-difluoro-3-oxobutanoate Property

Melting point:
-46°C(lit.)
Boiling point:
162 °C
Density 
1,61 g/cm3
refractive index 
1.407
Flash point:
68℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
clear liquid
pka
8.61±0.46(Predicted)
color 
Colorless to Almost colorless
InChIKey
CBDPWKVOPADMJC-UHFFFAOYSA-N
CAS DataBase Reference
352-24-9(CAS DataBase Reference)
EPA Substance Registry System
Ethyl 4,4-difluoroacetoacetate (352-24-9)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
10-36/37/38-36/38
Safety Statements 
26-36/37/39
RIDADR 
1993
WGK Germany 
3
Hazard Note 
Flammable
TSCA 
Yes
HazardClass 
3
HazardClass 
IRRITANT, FLAMMABLE
HS Code 
2918300090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1018
Product name
Ethyl 4,4-Difluoroacetoacetate
Purity
>96.0%(GC)
Packaging
5g
Price
$30
Updated
2021/12/16
TCI Chemical
Product number
E1018
Product name
Ethyl 4,4-Difluoroacetoacetate
Purity
>96.0%(GC)
Packaging
25g
Price
$90
Updated
2024/03/01
TRC
Product number
E678440
Product name
Ethyl 4,4-Difluoroacetoacetate
Packaging
10g
Price
$165
Updated
2021/12/16
TRC
Product number
E678440
Product name
Ethyl 4,4-Difluoroacetoacetate
Packaging
100g
Price
$745
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0026027
Product name
ETHYL 4,4-DIFLUOROACETOACETATE
Purity
95.00%
Packaging
5G
Price
$782.76
Updated
2021/12/16
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Ethyl 4,4-difluoro-3-oxobutanoate Chemical Properties,Usage,Production

Uses

Ethyl 4,4-Difluoroacetoacetate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.

Uses

Ethyl 4,4-difluoro-3-oxobutanoate is an intermediate used for the synthesis of pharmaceuticals such as potassium channel activators and β-alanine derived GABA-T antagonists.

Ethyl 4,4-difluoro-3-oxobutanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4,4-difluoro-3-oxobutanoate Suppliers

Americas 1 Brazil 1 Canada 2 China 282 Europe 1 France 1 Germany 6 India 17 Ireland 1 Italy 1 Japan 2 Russia 2 United Kingdom 7 United States 29 Global 353
Jinan Wanxingda Chemical Co., Ltd.
Tel
0531-88064106 18253116016
Fax
0531-88064109
Email
bruce@wxdchem.com
Country
China
ProdList
13
Advantage
58
West fluorine technology co., ltd
Tel
0531-85906692; 15588812394
Fax
86-0531-85906692
Email
325912682@qq.com
Country
China
ProdList
374
Advantage
58
Shangfluoro
Tel
021-021-65170832 13331983812
Email
qinba_2@163.com
Country
China
ProdList
301
Advantage
58
jinanzhonglanhuagongyouxiangongsi
Tel
0531-84215177 15169176553
Email
644658103@qq.com
Country
China
ProdList
22
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1392
Advantage
62
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View Lastest Price from Ethyl 4,4-difluoro-3-oxobutanoate manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9
Price
US $85.00-850.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-10
Hebei Guanlang Biotechnology Co., Ltd.
Product
Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-11-11
Zibo Shiji Zhonglian Medical Technology Co., Ltd.
Product
Ethyl 4,4-difluoro-3-oxobutanoate 352-24-9
Price
US $1.00/KG
Min. Order
25KG
Purity
99.0%
Supply Ability
1000KG/th
Release date
2023-06-15

352-24-9, Ethyl 4,4-difluoro-3-oxobutanoateRelated Search:

Ethyl 2-chloro-4,4,4-trifluoroacetoacetate Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate ETHYL PENTAFLUOROPROPIONYLACETATE Ethyl 4,4-difluoro-3-oxobutanoate Ethyl 4,4,4-trifluoroacetoacetate ETHYL HEPTAFLUOROBUTYRYLACETATE ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE ISOPROPYL 4,4,4-TRIFLUOROACETOACETATE ETHYL 2,2-DIFLUOROACETOACETATE Ethyl acetoacetate ETHYL 4,4,4-TRIFLUORO-2-(TRIPHENYLPHOSPHORANYLIDENE)ACETOACETATE 4,4,4-TRIFLUORO-ACETOACETIC ACID TERT-BUTYL ESTER 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER ETHYL 4,4,4-TRIFLUORO-2-METHOXY-3-OXOBUTYRATE ETHYL 3-([2-ACETYL-5-(TERT-BUTYL)-3-THIENYL]AMINO)-2-(2,2,2-TRIFLUOROACETYL)ACRYLATE METHYL 4-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)THIOPHENE-3-CARBOXYLATE METHYL 2-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)BENZOATE METHYL 2-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)THIOPHENE-3-CARBOXYLATE

  • AKOS MSC-0700
  • AKOS B016254
  • ETHYL 4,4-DIFLUORO-3-OXOBUTYRATE
  • ETHYL 4,4-DIFLUOROACETOACETATE
  • ART-CHEM-BB B016254
  • Difluoro aceto acetat
  • Ethyl 4,4-difluoro-3-oxobutyrate 90%
  • Ethyl4,4-difluoro-3-oxobutyrate90%
  • 4,4-Difluoroacetoacetic acid ethyl ester
  • Ethyl 4,4-difluoro-3-oxobutanoate
  • 4,4-Difluoro-3-oxo butyric acid ethyl ester
  • Ethyl 4,4-difluoro-3-oxobutanoate 90%
  • Ethyl 4,4-difluoroc
  • 4,4-difluoro-3-oxobutanoate
  • 3-Oxo-4,4-difluorobutanoic acid ethyl ester
  • 3-Oxo-4,4-difluorobutyric acid ethyl ester
  • 4-difluoro-3-oxobutanoate
  • Butanoic acid,4,4-difluoro-3-oxo-, ethyl ester
  • Ethyl-4 4-difluoroacetoacetate- >98% -purity (Pack 100GM X 3 Nos)
  • Ethyl 4,4-difluoro-3-oxobutyrate, Ethyl 4,4-difluoro-3-oxobutanoate
  • Ethyl 4,4-difluorocetoacetate SynonyMs Ethyl 4,4-difluoro-3-oxobutanoate
  • 4,4-difluoro-ethyl acetoacetate
  • Ethyl 4,4-difluorocetoacetate
  • 4,4-Difluoro-3-oxobutanoic acid ethyl ester
  • Ethyl 4,4-difluoro-3-ketobutyrate
  • Ethyl4,4-Difluoroacetoacetate&gt
  • TIANFU CHEM---Ethyl 4,4-difluoro-3-oxobutanoate
  • Butanoic acid, 4,4-difluoro-3-oxo-, ethyl ester (9CI, ACI)
  • 4,4-difluoro-3-oxo-Butanoic acid ethyl ester (9CI ACI)
  • 352-24-9
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