2-CYCLOHEXYLETHYL BROMIDE
- Product Name
- 2-CYCLOHEXYLETHYL BROMIDE
- CAS No.
- 1647-26-3
- Chemical Name
- 2-CYCLOHEXYLETHYL BROMIDE
- Synonyms
- NSC 6078;NSC 46808;2-CYCLOHEXYLETHYL BROMIDE;(2-bromoethyl)-cyclohexane;1-BROMO-2-CYCLOHEXYLETHANE;cyclohexane,(2-bromoethyl)-;Cyclohexane, (2-bromoethyl)-;2-Cyclohexylethyl bromide,98%;1-Bromo-2-cyclohexylethane 98%;2-CYCLOHEXYLETHYL BROMIDE ISO 9001:2015 REACH
- CBNumber
- CB4360412
- Molecular Formula
- C8H15Br
- Formula Weight
- 191.11
- MOL File
- 1647-26-3.mol
2-CYCLOHEXYLETHYL BROMIDE Property
- Melting point:
- 57°C
- Boiling point:
- 209 °C (lit.)
- Density
- 1.221 g/mL at 25 °C (lit.)
- refractive index
- 1.4900
- Flash point:
- 96°C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly)
- form
- Liquid
- color
- Clear colorless to slightly yellow
- BRN
- 1919816
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- JRQAAYVLPPGEHT-UHFFFAOYSA-N
- CAS DataBase Reference
- 1647-26-3(CAS DataBase Reference)
- EPA Substance Registry System
- Cyclohexane, (2-bromoethyl)- (1647-26-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 467952
- Product name
- 1-Bromo-2-cyclohexylethane
- Purity
- 98%
- Packaging
- 5g
- Price
- $98.3
- Updated
- 2025/07/31
- Product number
- B682815
- Product name
- 1-Bromo-2-cyclohexylethane
- Packaging
- 2.5g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 8366AA
- Product name
- (2-Bromoethyl)cyclohexane
- Packaging
- 5g
- Price
- $172
- Updated
- 2021/12/16
- Product number
- HCH0011609
- Product name
- 2-CYCLOHEXYLETHYL BROMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $432
- Updated
- 2021/12/16
- Product number
- HCH0011609
- Product name
- 2-CYCLOHEXYLETHYL BROMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $853.53
- Updated
- 2021/12/16
2-CYCLOHEXYLETHYL BROMIDE Chemical Properties,Usage,Production
Chemical Properties
2-CYCLOHEXYLETHYL BROMIDE is colourless to yellow liquid
Uses
2-CYCLOHEXYLETHYL BROMIDE is a reagent used in the cross-coupling and Grignard reactions. It is used in the synthesis of immunosuppressive agents consisting of 5-phenylalkoxypsoralens as well as agon ists for human vitamin-D resistant Rickets.
Uses
1-Bromo-2-cyclohexylethane may be used in the synthesis of 2-cyclohexylethyloxy-4-nitroaniline.
General Description
1-Bromo-2-cyclohexylethane is a halogenated hydrocarbon. Reaction of 1-bromo-2-cyclohexylethane with pillar[5]arene has been investigated.
Synthesis
4442-79-9
1647-26-3
General procedure for the synthesis of 2-cyclohexylethane bromoethane from 2-cyclohexylethanol: In a 1-liter round-bottomed flask fitted with a reflux condenser, 88.7 g (0.693 mol) of 2-cyclohexylethanol was added, followed by the slow addition of 164 g of concentrated sulfuric acid and 200 g of hydrobromic acid (48% aqueous), cooled in an ice bath. The reaction mixture was heated to reflux for 6 hours. After completion of the reaction, it was cooled to room temperature and the reaction was quenched by the addition of 400 g of ice. The aqueous phase was extracted with 400 ml of pentane and the organic layers were combined. The organic layer was washed sequentially with 2M NaOH solution and water and then dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure and the product was finally purified by vacuum distillation to give 112.7 g (85% yield) of 2-cyclohexylethyl bromide as a colorless oil.1H-NMR (400 MHz, CDCl3): δ= 3.40 (2H, t, CH2Br), 1.73-1.61 (m, 7H), 1.44 (m, 1H), 1.26-1.11 ( m, 3H), 0.92-0.84 (m, 2H) ppm.
References
[1] Journal of Medicinal Chemistry, 2011, vol. 54, # 6, p. 1693 - 1703
[2] Patent: US8299287, 2012, B2. Location in patent: Page/Page column 43
[3] Patent: JP6196581, 2017, B2. Location in patent: Paragraph 0156
[4] Journal of Medicinal Chemistry, 1992, vol. 35, # 12, p. 2253 - 2260
[5] Bulletin de la Societe Chimique de France, 1948, p. 586,588
2-CYCLOHEXYLETHYL BROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CYCLOHEXYLETHYL BROMIDE manufacturers
- Product
- 2-CYCLOHEXYLETHYL BROMIDE 1647-26-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 2000
- Release date
- 2025-06-11
- Product
- 2-CYCLOHEXYLETHYL BROMIDE 1647-26-3
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-26