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2-CYCLOHEXYLETHYL BROMIDE

Product Name
2-CYCLOHEXYLETHYL BROMIDE
CAS No.
1647-26-3
Chemical Name
2-CYCLOHEXYLETHYL BROMIDE
Synonyms
NSC 6078;NSC 46808;2-CYCLOHEXYLETHYL BROMIDE;(2-bromoethyl)-cyclohexane;1-BROMO-2-CYCLOHEXYLETHANE;cyclohexane,(2-bromoethyl)-;Cyclohexane, (2-bromoethyl)-;2-Cyclohexylethyl bromide,98%;1-Bromo-2-cyclohexylethane 98%;2-CYCLOHEXYLETHYL BROMIDE ISO 9001:2015 REACH
CBNumber
CB4360412
Molecular Formula
C8H15Br
Formula Weight
191.11
MOL File
1647-26-3.mol
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2-CYCLOHEXYLETHYL BROMIDE Property

Melting point:
57°C
Boiling point:
209 °C (lit.)
Density 
1.221 g/mL at 25 °C (lit.)
refractive index 
1.4900
Flash point:
96°C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly)
form 
Liquid
color 
Clear colorless to slightly yellow
BRN 
1919816
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
JRQAAYVLPPGEHT-UHFFFAOYSA-N
CAS DataBase Reference
1647-26-3(CAS DataBase Reference)
EPA Substance Registry System
Cyclohexane, (2-bromoethyl)- (1647-26-3)
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Safety

Risk Statements 
36/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29021900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
467952
Product name
1-Bromo-2-cyclohexylethane
Purity
98%
Packaging
5g
Price
$98.3
Updated
2025/07/31
TRC
Product number
B682815
Product name
1-Bromo-2-cyclohexylethane
Packaging
2.5g
Price
$55
Updated
2021/12/16
AK Scientific
Product number
8366AA
Product name
(2-Bromoethyl)cyclohexane
Packaging
5g
Price
$172
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0011609
Product name
2-CYCLOHEXYLETHYL BROMIDE
Purity
95.00%
Packaging
1G
Price
$432
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0011609
Product name
2-CYCLOHEXYLETHYL BROMIDE
Purity
95.00%
Packaging
5G
Price
$853.53
Updated
2021/12/16
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2-CYCLOHEXYLETHYL BROMIDE Chemical Properties,Usage,Production

Chemical Properties

2-CYCLOHEXYLETHYL BROMIDE is colourless to yellow liquid

Uses

2-CYCLOHEXYLETHYL BROMIDE is a reagent used in the cross-coupling and Grignard reactions. It is used in the synthesis of immunosuppressive agents consisting of 5-phenylalkoxypsoralens as well as agon ists for human vitamin-D resistant Rickets.

Uses

1-Bromo-2-cyclohexylethane may be used in the synthesis of 2-cyclohexylethyloxy-4-nitroaniline.

General Description

1-Bromo-2-cyclohexylethane is a halogenated hydrocarbon. Reaction of 1-bromo-2-cyclohexylethane with pillar[5]arene has been investigated.

Synthesis

4442-79-9

1647-26-3

General procedure for the synthesis of 2-cyclohexylethane bromoethane from 2-cyclohexylethanol: In a 1-liter round-bottomed flask fitted with a reflux condenser, 88.7 g (0.693 mol) of 2-cyclohexylethanol was added, followed by the slow addition of 164 g of concentrated sulfuric acid and 200 g of hydrobromic acid (48% aqueous), cooled in an ice bath. The reaction mixture was heated to reflux for 6 hours. After completion of the reaction, it was cooled to room temperature and the reaction was quenched by the addition of 400 g of ice. The aqueous phase was extracted with 400 ml of pentane and the organic layers were combined. The organic layer was washed sequentially with 2M NaOH solution and water and then dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure and the product was finally purified by vacuum distillation to give 112.7 g (85% yield) of 2-cyclohexylethyl bromide as a colorless oil.1H-NMR (400 MHz, CDCl3): δ= 3.40 (2H, t, CH2Br), 1.73-1.61 (m, 7H), 1.44 (m, 1H), 1.26-1.11 ( m, 3H), 0.92-0.84 (m, 2H) ppm.

References

[1] Journal of Medicinal Chemistry, 2011, vol. 54, # 6, p. 1693 - 1703
[2] Patent: US8299287, 2012, B2. Location in patent: Page/Page column 43
[3] Patent: JP6196581, 2017, B2. Location in patent: Paragraph 0156
[4] Journal of Medicinal Chemistry, 1992, vol. 35, # 12, p. 2253 - 2260
[5] Bulletin de la Societe Chimique de France, 1948, p. 586,588

2-CYCLOHEXYLETHYL BROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CYCLOHEXYLETHYL BROMIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
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64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
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50
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
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Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
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View Lastest Price from 2-CYCLOHEXYLETHYL BROMIDE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.
Product
2-CYCLOHEXYLETHYL BROMIDE 1647-26-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
2000
Release date
2025-06-11
Henan Fengda Chemical Co., Ltd
Product
2-CYCLOHEXYLETHYL BROMIDE 1647-26-3
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-26

1647-26-3, 2-CYCLOHEXYLETHYL BROMIDERelated Search:


  • 2-CYCLOHEXYLETHYL BROMIDE
  • 1-BROMO-2-CYCLOHEXYLETHANE
  • (2-bromoethyl)-cyclohexane
  • Cyclohexane, (2-bromoethyl)-
  • cyclohexane,(2-bromoethyl)-
  • 1-Bromo-2-cyclohexylethane~(2-Bromoethyl)cyclohexane
  • 2-Cyclohexylethyl bromide,98%
  • NSC 46808
  • NSC 6078
  • 1-Bromo-2-cyclohexylethane 98%
  • 2-CYCLOHEXYLETHYL BROMIDE ISO 9001:2015 REACH
  • 1647-26-3
  • C8H15Br
  • C6H11CH2CH2Br
  • HALOGEN
  • Building Blocks
  • Alkyl
  • Halogenated Hydrocarbons
  • Organic Building Blocks