(R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE

Product Name: (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE
CAS No.: 173336-98-6
Chemical Name: (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE
Synonyms: (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE;(R)-5-(Aminomethyl)-2-pyrrolidinone;(5R)-5-(aminomethyl)pyrrolidin-2-one;(5R)-5-(Aminomethyl)-2-pyrrolidinone;2-Pyrrolidinone, 5-(aminomethyl)-, (5R)-
CBNumber: CB4362946
Molecular Formula: C5H10N2O
Formula Weight: 114.15
MOL File: 173336-98-6.mol

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(R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE Property

Boiling point:: 313.9±15.0 °C(Predicted)
Density: 1.076±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 16.06±0.40(Predicted)

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A578048
Product name: (R)-5-Aminomethyl-pyrrolidin-2-one
Packaging: 100mg
Price: $130
Updated: 2021/12/16

TRC

Product number: A578048
Product name: (R)-5-Aminomethyl-pyrrolidin-2-one
Packaging: 50mg
Price: $90
Updated: 2021/12/16

Activate Scientific

Product number: AS42057-A
Product name: (R)-5-(Aminomethyl)pyrrolidin-2-one
Purity: 95+% ee
Packaging: 250mg
Price: $324
Updated: 2021/12/16

Activate Scientific

Product number: AS42057-A
Product name: (R)-5-(Aminomethyl)pyrrolidin-2-one
Purity: 95+% ee
Packaging: 1g
Price: $670
Updated: 2021/12/16

AK Scientific

Product number: X5489
Product name: (R)-5-Aminomethyl-pyrrolidin-2-one
Packaging: 250mg
Price: $532
Updated: 2021/12/16

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(R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE Chemical Properties,Usage,Production

Synthesis

173828-76-7

173336-98-6

General procedure for the synthesis of (R)-5-aminomethylpyrrolidin-2-one from the compound (CAS: 173828-76-7): (R)-5-(azidomethyl)pyrrolidin-2-one (150 mg, 1.07 mmol) was dissolved in methanol and palladium/carbon catalyst was added. The reaction mixture was transferred to an autoclave and after three degassing operations, hydrogen was charged to 30 psi and the reaction was stirred at room temperature for 30 min. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the title compound (R)-5-(aminomethyl)pyrrolidin-2-one (92 mg, 75% yield). Low resolution mass spectrometry (LRMS) showed (M+H)+ m/z of 115.1.

References

[1] Journal of Medicinal Chemistry, 2009, vol. 52, # 13, p. 3902 - 3914
[2] Patent: WO2008/16643, 2008, A2. Location in patent: Page/Page column 245-246
[3] Tetrahedron, 1995, vol. 51, # 48, p. 13309 - 13320

(R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE Suppliers

China 34 India 1 United Kingdom 2 United States 7 Global 44

Nanjing Chemlin Chemical Co., Ltd

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View Lastest Price from (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE 173336-98-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Career Henan Chemical Co

Product: (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE 173336-98-6
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2019-12-26

173336-98-6, (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONERelated Search:

(S)-5-AMINOMETHYL-PYRROLIDIN-2-ONE Fasoracetam 5-AMINOMETHYL-PYRROLIDIN-2-ONE (R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE (2S,2'R)-[2,2']BIPYRROLIDINYL-5,5'-DIONE D-PYR-D-PHE-D-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2

(R)-5-AMINOMETHYL-PYRROLIDIN-2-ONE

(5R)-5-(aminomethyl)pyrrolidin-2-one

(R)-5-(Aminomethyl)-2-pyrrolidinone

2-Pyrrolidinone, 5-(aminomethyl)-, (5R)-

(5R)-5-(Aminomethyl)-2-pyrrolidinone

173336-98-6

17336-98-6

pharmacetical