8-Anilino-1-naphthalenesulfonic acid ammonium salt Property

Melting point:

242-244 °C(lit.)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

NaOH: soluble1 N

form 

crystalline

color 

dark green

Water Solubility 

Soluble in water, 1N NaOH, and methanol.

Sensitive 

Light & Air Sensitive & Hygroscopic

λmax

375nm(lit.)

BRN 

3581235

InChI

InChI=1S/C16H13NO3S.H3N/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;/h1-11,17H,(H,18,19,20);1H3

InChIKey

SYNRZVIFUGIQFF-UHFFFAOYSA-N

SMILES

S(C1=CC=CC2=CC=CC(NC3C=CC=CC=3)=C12)(O)(=O)=O.N

CAS DataBase Reference

28836-03-5(CAS DataBase Reference)

EPA Substance Registry System

1-Naphthalenesulfonic acid, 8-(phenylamino)-, monoammonium salt (28836-03-5)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

3-8-10-23

TSCA 

Yes

HS Code 

29214980

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

8-Anilino-1-naphthalenesulfonic acid ammonium salt Chemical Properties,Usage,Production

Chemical Properties

8-Anilinonaphthalene-1-sulfonic acid ammonium salt is a light yellow to yellow-green solid. It is primarily utilized as a dye intermediate in the production of weak acid dark blue 5R and weak acid black BR.

Uses

8-Anilino-1-naphthalenesulfonic Acid Ammonium Salt is a fluorescent probe for protein studies. It is used as sensitive indicator of protein folding, conformational changes and for protein studies. It can also be used in engineering or chemical process of broad-spectrum tunable photoluminescent nanomaterials constructed from modular light-harvesting platform based on macrocyclic amphiphiles.

Application

ANS forms an inclusion complex with cyclodextrin. Such model systems are useful to mimic biological recognition and can be studied by measuring the change in fluorescence of free-ANS to complexed-ANS. When ANS enters the hydrophobic core of cyclodestrin, it′s fluorescence increases . Utilized in the reagent phase of a sodium-selective fiber-optic sensor. The reagent phase also contains a copper(II) polyelectrolyte, which binds to ANSA in the absence of sodium and quenches the fluorescence. In the presence of sodium, ANSA forms a cationic complex creating ion-pairs, causing it to fluoresce . ANS is often incorporated into di-block polymers and can be released by changes in the local environment (i.e., temperature, pH, etc.) . ANS is commonly used as a fluorescence probe to investigate molecular assemblies of surfactants and amphiphilic polymers because a blue shift of the emission maximum indicates the fluorophore is located in less polar media . Fluorescent probe for protein studies using methodologies such as steady-state and dynamic fluorescence measurements.