ChemicalBook > CAS DataBase List > 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

Product Name
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
CAS No.
36507-30-9
Chemical Name
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
Synonyms
C07496;GP 49-023;(11-epoxide-d10);carbamazepineepoxide;carbamazepine10,11-oxide;10,11-epoxycarbamazepine;Carbamazepine Impurity 12;CARBAMAZEPINE 10,11-EPOXIDE;CarbaMazepine-10,11-epoxide-d10;Carbamazepine-10,11-epoxide solution
CBNumber
CB4364889
Molecular Formula
C15H12N2O2
Formula Weight
252.27
MOL File
36507-30-9.mol
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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Property

Melting point:
204-206°C
Boiling point:
390.2±52.0 °C(Predicted)
Density 
1.377±0.06 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Solid
pka
13.91±0.20(Predicted)
color 
White
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Safety

Hazard Codes 
Xn,N,T,F
Risk Statements 
22-36/37/38-51/53-39/23/24/25-23/24/25-11
Safety Statements 
26-36-61-45-36/37-16-7
RIDADR 
2811
WGK Germany 
3
RTECS 
HQ4430000
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C4206
Product name
Carbamazepine 10,11-epoxide
Purity
analytical standard
Packaging
5mg
Price
$83.7
Updated
2024/03/01
Sigma-Aldrich
Product number
C-121
Product name
Carbamazepine-10,11-epoxide solution
Purity
1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$95.5
Updated
2024/03/01
Sigma-Aldrich
Product number
93203
Product name
Carbamazepine 10,11-epoxide
Purity
analytical standard
Packaging
25MG
Price
$619
Updated
2022/05/15
Sigma-Aldrich
Product number
C4206
Product name
Carbamazepine 10,11-epoxide
Purity
analytical standard
Packaging
25mg
Price
$317
Updated
2024/03/01
TRC
Product number
C175850
Product name
Carbamazepine 10,11-epoxide
Packaging
50mg
Price
$295
Updated
2021/12/16
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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.

Uses

A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.

Uses

A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC

Definition

ChEBI: An epoxide and metabolite of carbamazepine.

General Description

Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.

Biochem/physiol Actions

First metabolite of carbamazepine

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Suppliers

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36507-30-9, 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDERelated Search:


  • CARBAMAZEPINE 10,11-EPOXIDE
  • 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
  • 1A,10BETA-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
  • 10,11-epoxycarbamazepine
  • 1a,10b-dihydro-6h-dibenz(b,f)oxiren(d)azepine-6-carboxamide
  • carbamazepine10,11-oxide
  • carbamazepineepoxide
  • 10,11-Dihydro-10,11-epoxy-5H-dibenzo[b,f]azepine-5-carboxamide
  • 1a,10b-Dihydro-6H-dibenz[b,f]oxireno[d]azepine-6-carboxamide
  • (11-epoxide-d10)
  • 6H-Dibenz[b,f]oxireno[d]azepine-6-carboxaMide,1a,10b-dihydro-
  • Carbamazepine-10,11-epoxide solution
  • f)oxiren(d)azepine-6-carboxamide,1a,10b-dihydro-6h-dibenz(
  • 10,11-Dihydro-10,11-epoxycarbamazepine
  • 1a,10b-Dihdyro-6H-dibenzo[b,f]oxireno[d]azepine-6-carboxamide
  • GP 49-023
  • 10,11-Epoxycarbamazepine (Metabolite)
  • 1aH-dibenzo[b,f]oxireno[2,3-d]azepine-6(10bH)-carboxaMide
  • CarbaMazepine-10,11-epoxide-d10
  • C07496
  • Carbamazepine Impurity 12
  • 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide 10,11-epoxide
  • Carbamazepine 10,11-Epoxide-d8 (Major)Q: What is Carbamazepine 10,11-Epoxide-d8 (Major) Q: What is the CAS Number of Carbamazepine 10,11-Epoxide-d8 (Major)
  • 10,11-dihydro 10-11-epoxy-carbamazepineQ: What is 10,11-dihydro 10-11-epoxy-carbamazepine Q: What is the CAS Number of 10,11-dihydro 10-11-epoxy-carbamazepine Q: What is the storage condition of 10,11-dihydro 10-11-epoxy-carbamazepine Q: What are the applications of 10,11-dihydro 10-11-epoxy-carbamazepine
  • Carbamazepine 10,11 epoxide,Carbamazepine 10,11epoxide
  • Carbamazepine-10,11-epoxide in methanol
  • 36507-30-9
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