Cynaroside
Effects- Product Name
- Cynaroside
- CAS No.
- 5373-11-5
- Chemical Name
- Cynaroside
- Synonyms
- LUTEOLIN-7-O-GLUCOSIDE;luteoloside;PETUNIDIN;LUTEOLIN-7-GLUCOSIDE;Galuteolin;cinaroside;glucoluteolin;Luteolin 7-O-β-D-glucopyranoside;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy-;CYNAROSIDE
- CBNumber
- CB4369516
- Molecular Formula
- C21H20O11
- Formula Weight
- 448.38
- MOL File
- 5373-11-5.mol
Cynaroside Property
- Melting point:
- 256～258℃
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- Boiling point:
- 838.1±65.0 °C(Predicted)
- Density
- 1.713±0.06 g/cm3(Predicted)
- pka
- 6.10±0.40(Predicted)
- form
- Solid
- color
- Yellow to Very Dark Yellow
- Stability:
- Hygroscopic
- InChIKey
- PEFNSGRTCBGNAN-QNDFHXLGSA-N
- SMILES
- C1(C2=CC=C(O)C(O)=C2)OC2=C(C(O)=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=C2)C(=O)C=1 |&1:17,18,20,22,24,r|
- LogP
- -0.090 (est)
- CAS DataBase Reference
- 5373-11-5(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- 1370837
- Product name
- Luteolin 7-O-Glucoside
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 30mg
- Price
- $692
- Updated
- 2024/03/01
- Product number
- 03600585
- Product name
- Luteolin 7-glucoside
- Purity
- primary pharmaceutical reference standard
- Packaging
- 10mg
- Price
- $475
- Updated
- 2024/03/01
- Product number
- 25141
- Product name
- Luteoloside
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 25141
- Product name
- Luteoloside
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- 74284
- Product name
- Luteolin 7-O-β-D-glucoside
- Purity
- ≥98.0% (HPLC)
- Packaging
- 10mg
- Price
- $536
- Updated
- 2024/03/01
Cynaroside Chemical Properties,Usage,Production
Effects
Luteolin has a strong bactericidal effect on the respiratory tract, and it is the main active ingredient in the treatment of bronchitis in Qinglan, a unique medicinal material in Xinjiang. Lowers the role of cholesterol in atherosclerosis and enhances capillary relaxation.
Description
Luteolin-7-O-glucoside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. Luteoloside blocks 3C protease activity (IC50 = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM). It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg. Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod .
Chemical Properties
Off-white powder
Uses
Luteolin 7-Glucoside is a strong antioxidant ant radical scavenger. Used in cancer prevention.
Definition
ChEBI: A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Cynaroside Preparation Products And Raw materials
Raw materials
Preparation Products
Cynaroside Suppliers
- Tel
- --
- Fax
- --
- info-tech@nacalai.co.jp
- Country
- Japan
- ProdList
- 6046
- Advantage
- 75
View Lastest Price from Cynaroside manufacturers
- Product
- Cynaroside 5373-11-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
- Product
- Cynaroside 5373-11-5
- Price
- US $30.00-10.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-11-15
- Product
- Cynaroside 5373-11-5
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-09-18