ChemicalBook > CAS DataBase List > 5-Hydroxyvanillin

5-Hydroxyvanillin

Product Name
5-Hydroxyvanillin
CAS No.
3934-87-0
Chemical Name
5-Hydroxyvanillin
Synonyms
3,4-DIHYDROXY-5-METHOXYBENZALDEHYDE;3,4-dihydroxy-5-methoxy benzyaldehyde;5-hydroxyvanillin;AKOS BBS-00007007;5-Hydroxyvanilline;5-Methoxyprotocatechualdehyde;5-methoxy-protocatechualdehyd;Protocatechualdehyde, 5-methoxy-;4,5-Dihydroxy-3-methoxybenzaldehyde;3-METHOXY-4,5-DIHYDROXYBENZALDEHYDE
CBNumber
CB4378653
Molecular Formula
C8H8O4
Formula Weight
168.15
MOL File
3934-87-0.mol
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5-Hydroxyvanillin Property

Melting point:
131-134°C
Boiling point:
339.9±37.0 °C(Predicted)
Density 
1.378±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
7.63±0.23(Predicted)
form 
solid
color 
Light grey/ brown
InChI
InChI=1S/C8H8O4/c1-12-7-3-5(4-9)2-6(10)8(7)11/h2-4,10-11H,1H3
InChIKey
RRKMWVISRMWBAL-UHFFFAOYSA-N
SMILES
C(=O)C1=CC(OC)=C(O)C(O)=C1
LogP
1.050 (est)
CAS DataBase Reference
3934-87-0(CAS DataBase Reference)
NIST Chemistry Reference
3,4-Dihydroxy-5-methoxybenzaldehyde(3934-87-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
CU5620000
HS Code 
2912490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
464120
Product name
3,4-Dihydroxy-5-methoxybenzaldehyde
Purity
96%
Packaging
1g
Price
$71.4
Updated
2025/07/31
Sigma-Aldrich
Product number
464120
Product name
3,4-Dihydroxy-5-methoxybenzaldehyde
Purity
96%
Packaging
5g
Price
$226
Updated
2025/07/31
TCI Chemical
Product number
D4479
Product name
3,4-Dihydroxy-5-methoxybenzaldehyde
Purity
min. 98.0 %
Packaging
1G
Price
$146
Updated
2025/07/31
TCI Chemical
Product number
D4479
Product name
3,4-Dihydroxy-5-methoxybenzaldehyde
Purity
min. 98.0 %
Packaging
5G
Price
$438
Updated
2025/07/31
TRC
Product number
D480840
Product name
3,​4-​Dihydroxy-​5-​methoxybenzaldehyde
Packaging
1g
Price
$100
Updated
2021/12/16
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5-Hydroxyvanillin Chemical Properties,Usage,Production

Chemical Properties

Crystallized. Melting point 130-131°C (132.5-134°C).

Uses

3,4-Dihydroxy-5-methoxybenzaldehyde may be used for the preparation of 3,4-dihydroxy-6-methoxy-β-nitrostyrene and 5-hydroxyconiferyl alcohol.

Synthesis Reference(s)

Synthetic Communications, 18, p. 507, 1988 DOI: 10.1080/00397918808060744

General Description

3,4-Dihydroxy-5-methoxybenzaldehyde can be obtained by reactting 5-iodovaniliin with sodium hydroxide and copper sulfate solution.

Synthesis

The bromination reaction of vanillal and bromine generate 5-bromovanillal, which is then reacted with sodium hydroxide solution under the participation of copper powder to give 5-Hydroxyvanillin.

5-Hydroxyvanillin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Hydroxyvanillin manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
5-Hydroxyvanillin 3934-87-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-15
R&D Scientific Inc.
Product
3,4-Dihydroxy-5-methoxybenzaldehyde 3934-87-0
Price
US $900.00/g
Min. Order
1g
Purity
97
Supply Ability
500 Kg
Release date
2024-03-20
Career Henan Chemical Co
Product
5-Hydroxyvanillin 3934-87-0
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-12

3934-87-0, 5-HydroxyvanillinRelated Search:


  • 5-Hydroxyvanilline
  • 3,4-dihydroxy-5-methoxy-benzaldehyd
  • 5-methoxy-protocatechualdehyd
  • 5-Methoxyprotocatechualdehyde
  • Benzaldehyde, 3,4-dihydroxy-5-methoxy-
  • Protocatechualdehyde, 5-methoxy-
  • 5-METHOXY-3,4-DIHYDROXYBENZALDEHYDE
  • 5-hydroxyvanillin
  • 3,4-DIHYDROXY-5-METHOXYBENZALDEHYDE
  • 3-METHOXY-4,5-DIHYDROXYBENZALDEHYDE
  • 4,5-Dihydroxy-3-methoxybenzaldehyde
  • 3,4-dihydroxy-5-methoxy benzyaldehyde
  • AKOS BBS-00007007
  • 3,4-Dihydroxy-5-methoxybenzaldehdye
  • 5-Hydroxyvanillin ISO 9001:2015 REACH
  • 3934-87-0
  • 23934-87-0
  • HO2C6H2OCH3CHO
  • CH3OC6H2OH2CHO
  • C8
  • Carbonyl Compounds
  • Building Blocks
  • Aldehydes
  • Organic Building Blocks
  • Benzaldehyde
  • Aldehydes
  • C8
  • Carbonyl Compounds
  • FINE Chemical & INTERMEDIATES
  • Aromatic Aldehydes & Derivatives (substituted)