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ALPHA-HEMOLYSIN

Product Name
ALPHA-HEMOLYSIN
CAS No.
94716-94-6
Chemical Name
ALPHA-HEMOLYSIN
Synonyms
α-HeMolysin;ALPHA-TOXIN;ALPHA-HEMOLYSIN;STAPHYLOCOCCUS AUREUS;Staphylococcus piscifermentans;ALPHA-TOXIN, STAPHYLOCOCCUS AUREUS;α-HemolysinfromStaphylococcusaureus;α-Hemolysin (Staphylococcus aureus);α-hemolysin from staphylococcus aureus;A-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS
CBNumber
CB4384087
Formula Weight
0
MOL File
Mol file
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ALPHA-HEMOLYSIN Property

storage temp. 
2-8°C
solubility 
H2O: soluble0.49 - 0.51mg/mL
form 
lyophilized powder
color 
White to off-white
biological source
Staphylococcus aureus
Water Solubility 
H2O: soluble 0.49-0.51mg/mL
Specific Activity
≥10,000units/mg protein
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Safety

Hazard Codes 
Xn
Risk Statements 
22-21/22
Safety Statements 
36-36/37
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H371May cause damage to organs

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H9395
Product name
α-Hemolysin from Staphylococcus aureus
Purity
lyophilized powder, Protein ~60?% by Lowry, ≥10,000?units/mg protein
Packaging
0.5MG
Price
$467
Updated
2025/07/31
Sigma-Aldrich
Product number
H9395
Product name
α-Hemolysin from Staphylococcus aureus
Purity
lyophilized powder, Protein ~60 % by Lowry, ≥10,000 units/mg protein
Packaging
1mg
Price
$879
Updated
2025/07/31
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ALPHA-HEMOLYSIN Chemical Properties,Usage,Production

Uses

α-Hemolysin was used in a study to test the efflux pump and haemolysin activity of Escherichia coli of dairy origin. It was also used to test its adaptation to benzalkonium chloride and the effect of ciprofloxacin on biofilm formation.

Uses

ALPHA-HEMOLYSIN was used in a study to test the efflux pump and haemolysin activity of Escherichia coli of dairy origin. It was also used to test its adaptation to benzalkonium chloride and the effect of ciprofloxacin on biofilm formation.

General Description

α-Hemolysin, a pore-forming cytotoxin is an extracellular protein secreted by most strains of pathogenic?Staphylococcus aureus. It is secreted as a water-soluble monomer and is a small β-barrel protein.

Biochem/physiol Actions

α-Hemolysin is selectively hemolytic and the monomeric form binds to a membrane and specific receptors are not required for binding. Upon binding to biological membranes and/or artificial membranes, self-oligomerization occurs, resulting in ring structures (hexameric aggregates) believed to represent transmembrane pores, which are permeable to ions and small metabolites. It has a marked preference for rabbit red blood cells. α-hemolysin stimulates cellular phospholipases and induces a Ca2+?influx. It leads to membrane disruption of the endothelial barrier and leakage of cytoplasmic components and osmotic lysis of the cells. α-hemolysin is implicated in the pathogenesis of sepsis.

ALPHA-HEMOLYSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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94716-94-6, ALPHA-HEMOLYSINRelated Search:


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