ChemicalBook > CAS DataBase List > Z-3-CYCLOHEXYL-L-ALANINE

Z-3-CYCLOHEXYL-L-ALANINE

Product Name
Z-3-CYCLOHEXYL-L-ALANINE
CAS No.
25341-42-8
Chemical Name
Z-3-CYCLOHEXYL-L-ALANINE
Synonyms
Z-CHA-OH;Z-L-Cha-OH;Cbz-L-CHA-OH;Z-Cha-OH 98%;Z-Cha-OH (Syrup);Z-L-CYCLOHEXYLALANINE;CBZ-L-CYCLOHEXYLALANINE;Z-3-CYCLOHEXYL-L-ALANINE;Z-BETA-CYCLOHEXYLALANINE;Z-β-cyclohexyl-L-alanine
CBNumber
CB4384582
Molecular Formula
C17H23NO4
Formula Weight
305.37
MOL File
25341-42-8.mol
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Z-3-CYCLOHEXYL-L-ALANINE Property

Boiling point:
501.4±43.0 °C(Predicted)
Density 
1.167
storage temp. 
2-8°C
pka
4.00±0.10(Predicted)
Appearance
Colorless to light yellow Oil
optical activity
Consistent with structure
InChI
InChI=1/C17H23NO4/c19-16(20)15(11-13-7-3-1-4-8-13)18-17(21)22-12-14-9-5-2-6-10-14/h2,5-6,9-10,13,15H,1,3-4,7-8,11-12H2,(H,18,21)(H,19,20)/t15-/s3
InChIKey
MNABZONTQXNLDT-UJHUVDBMNA-N
SMILES
[C@H](C(=O)O)(NC(=O)OCC1=CC=CC=C1)CC1CCCCC1 |&1:0,r|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B194245
Product name
(S)-2-(((Benzyloxy)carbonyl)amino)-3-cyclohexylpropanoicAcid
Packaging
250mg
Price
$55
Updated
2021/12/16
Activate Scientific
Product number
AS102656
Product name
Cbz-3-cyclohexyl-L-alanine
Purity
95% ee
Packaging
5G
Price
$78
Updated
2021/12/16
Chem-Impex
Product number
12428
Product name
Z-β-cyclohexyl-L-alanine
Purity
≥ 98% (HPLC)
Packaging
25G
Price
$110
Updated
2021/12/16
Chem-Impex
Product number
12428
Product name
Z-β-cyclohexyl-L-alanine,98%(HPLC)
Purity
98%(HPLC)
Packaging
1G
Price
$14
Updated
2021/12/16
Chem-Impex
Product number
12428
Product name
Z-β-cyclohexyl-L-alanine
Purity
≥ 98% (HPLC)
Packaging
5G
Price
$30
Updated
2021/12/16
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Z-3-CYCLOHEXYL-L-ALANINE Chemical Properties,Usage,Production

Chemical Properties

Transparent, yellow oil

Synthesis

27527-05-5

501-53-1

25341-42-8

General procedure: to a solution of (S)-2-amino-3-cyclohexylpropionic acid (10 g, 58.4 mmol) in THF/H2O (1:1, 292 ml) was added benzyl chloroformate (9.93 g, 58.4 mmol) and K2CO3 (9.67 g, 70.09 mmol). The reaction mixture was stirred at 0 °C for 0.5 h, followed by stirring at room temperature overnight. After completion of the reaction, the reaction mixture was diluted with EtOAc (200 ml) and the pH was adjusted to about 2 with 6N HCl. The organic layer was separated, washed with brine, dried over MgSO4, filtered and concentrated to give the solid product (S)-2-(((benzyloxy)carbonyl)amino)-3-cyclohexylpropanoic acid in 95% yield (17 g). Results of mass spectrometry analysis: MS (m/z): 306 (M + H).

References

[1] Patent: WO2006/29210, 2006, A2. Location in patent: Page/Page column 47

Z-3-CYCLOHEXYL-L-ALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-3-CYCLOHEXYL-L-ALANINE Suppliers

Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel
0523-86132544 15366717810
Fax
0523-86201489
Email
sales@thbiochem.com
Country
China
ProdList
370
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55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
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66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
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64
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
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62
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
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55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4720
Advantage
55
TAIZHOU TIANHONG BIOCHEMICALS CO., LTD
Tel
15366717998
Fax
0523-86201489
Email
thbiochem@126.com
Country
China
ProdList
87
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
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55
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View Lastest Price from Z-3-CYCLOHEXYL-L-ALANINE manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Cbz-L-Cha-OH 25341-42-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-01-14
Career Henan Chemical Co
Product
Z-3-CYCLOHEXYL-L-ALANINE 25341-42-8
Price
US $1.00/g
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-09

25341-42-8, Z-3-CYCLOHEXYL-L-ALANINERelated Search:


  • Z-BETA-CYCLOHEXYLALANINE
  • Z-CHA-OH
  • Z-3-CYCLOHEXYL-L-ALANINE
  • Z-L-CYCLOHEXYLALANINE
  • CBZ-L-CYCLOHEXYLALANINE
  • (S)-2-(benzyloxycarbonylamino)-3-cyclohexylpropanoic acid
  • (2S)-[(Benzyloxycarbonyl)amino]-3-cyclohexylpropionic acid
  • (S)-N-(Benzyloxycarbonyl)cyclohexylalanine
  • N-Benzyloxycarbonyl-L-3-cyclohexylalanine
  • (S)-2-benzyloxycarbonylaMino-3-cyclohexylpropionic acid
  • Cbz-L-CHA-OH
  • (2S)-2-{[(benzyloxy)carbonyl]aMino}-3-cyclohexylpropanoic acid
  • Cbz-3-cyclohexyl-L-alanine
  • Z-β-cyclohexyl-L-alanine
  • Cbz-L-3-Cyclohexyl Alanine
  • N-Cbz-3-cyclohexyl-L-alanine
  • (2S)-3-cyclohexyl-2-(phenylmethoxycarbonylamino)propanoic acid
  • Z-L-Cha-OH
  • Z-β-cyclohexyl-L-alanine≥ 98% (HPLC)
  • Z-Cha-OH (Syrup)
  • Cyclohexanepropanoic acid, α-[[(phenylmethoxy)carbonyl]amino]-, (αS)-
  • (2S)-3-cyclohexyl-2-(phenylmethoxycarbonylamino)propanoicaci
  • Z-3-CYCLOHEXYL-L-ALANINE USP/EP/BP
  • Cyclohexanepropanoicacid, a-[[(phenylmethoxy)carbonyl]amino]-, (aS)-
  • Z-Cha-OH 98%
  • (S)-2-(((Benzyloxy)carbonyl)amino)-3-cyclohexylpropanoic acid - [B91578]
  • 25341-42-8
  • Alanine Derivatives
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Peptide Synthesis