ChemicalBook > CAS DataBase List > (RS)-3,5-DHPG

(RS)-3,5-DHPG

Product Name
(RS)-3,5-DHPG
CAS No.
146255-66-5
Chemical Name
(RS)-3,5-DHPG
Synonyms
2-amino-2-(3,5-dihydroxyphenyl)acetic acid;3,5-dihydroxyphenylglycine;(RS)-3,5-DHPG;DHPG ((RS)-3,5-DHPG);(RS)-3,5-DIHYDROXYPHENYLGLYCINE;DL-ALPHA-(3,5-DIHYDROXYPHENYL)GLYCINE;Benzeneacetic acid, α-amino-3,5-dihydroxy-;a-Amino-3,5-dihydroxy-benzeneacetic acid HCl;(R,S)-3,5-DHPG, group I mGlu receptor agonist;DHPG,mGluR,Inhibitor,inhibit,Metabotropic glutamate receptors
CBNumber
CB4396488
Molecular Formula
C8H9NO4
Formula Weight
183.16
MOL File
146255-66-5.mol
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(RS)-3,5-DHPG Property

Boiling point:
448.8±33.0 °C(Predicted)
Density 
1.550±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 1 mg/ml; Water: 1 mg/ml
form 
A solid
pka
1.77±0.10(Predicted)
color 
White
Water Solubility 
Soluble in water (10mM)
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D450028
Product name
(RS)-3,5-DHPG
Packaging
10mg
Price
$90
Updated
2021/12/16
TRC
Product number
D450028
Product name
(RS)-3,5-DHPG
Packaging
100mg
Price
$720
Updated
2021/12/16
ChemScene
Product number
CS-0020572
Product name
DHPG
Purity
99.31%
Packaging
500mg
Price
$1100
Updated
2021/12/16
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(RS)-3,5-DHPG Chemical Properties,Usage,Production

Uses

(RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson''s disease.

Definition

ChEBI: A glycine derivative that is L-alpha-phenylglycine substituted at positions 3 and 5 on the phenyl ring by hydroxy groups.

IC 50

mGluR 1; mGluR 5

storage

-20°C (desiccate). Protect from light.

(RS)-3,5-DHPG Preparation Products And Raw materials

Raw materials

Preparation Products

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(RS)-3,5-DHPG Suppliers

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146255-66-5, (RS)-3,5-DHPGRelated Search:


  • DL-ALPHA-(3,5-DIHYDROXYPHENYL)GLYCINE
  • (RS)-3,5-DHPG
  • (RS)-3,5-DIHYDROXYPHENYLGLYCINE
  • 3,5-dihydroxyphenylglycine
  • Benzeneacetic acid, α-amino-3,5-dihydroxy-
  • 2-amino-2-(3,5-dihydroxyphenyl)acetic acid
  • a-Amino-3,5-dihydroxy-benzeneacetic acid HCl
  • DHPG,mGluR,Inhibitor,inhibit,Metabotropic glutamate receptors
  • DHPG ((RS)-3,5-DHPG)
  • (R,S)-3,5-DHPG, group I mGlu receptor agonist
  • 146255-66-5