ChemicalBook > CAS DataBase List > N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide

N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide

Product Name
N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
CAS No.
349438-74-0
Chemical Name
N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
Synonyms
CK1-IN-3;WAY-296817;WAY296817,WAY 296817;Benzeneacetamide, 2-methoxy-N-(6-methoxy-2-benzothiazolyl)-;N-(6-Methoxybenzo[d]thiazol-2-yl)-2-(2-methoxyphenyl)acetamide;N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
CBNumber
CB44020822
Molecular Formula
C17H16N2O3S
Formula Weight
328.39
MOL File
349438-74-0.mol
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N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Property

Density 
1.323±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
10.22±0.70(Predicted)
form 
Solid
color 
Gray to brown
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Hazard and Precautionary Statements (GHS)

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N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Chemical Properties,Usage,Production

Uses

CK1-IN-3 (compound 51) is a AC1 inhibitor with an IC50s 2.22 μM for CK-1δ[1][2].

in vivo

CK1-IN-3 (compound 35) (100 nM; feed) significantly extendes fly lifespan to 36.17 days[2].

IC 50

CK1δ: 2.22 μM (IC50)

References

[1] Ana MARTíNEZ GIL, et al. Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases. WO2014114825A1.
[2] Salado IG, et al. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. J Med Chem. 2014 Mar 27;57(6):2755-72. DOI:10.1021/jm500065f

N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Suppliers

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349438-74-0, N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamideRelated Search:


  • N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
  • WAY-296817
  • WAY296817,WAY 296817
  • Benzeneacetamide, 2-methoxy-N-(6-methoxy-2-benzothiazolyl)-
  • CK1-IN-3
  • N-(6-Methoxybenzo[d]thiazol-2-yl)-2-(2-methoxyphenyl)acetamide
  • 349438-74-0