2-Benzofurancarboxylic acid ethyl ester
- Product Name
- 2-Benzofurancarboxylic acid ethyl ester
- CAS No.
- 3199-61-9
- Chemical Name
- 2-Benzofurancarboxylic acid ethyl ester
- Synonyms
- Ethyl CouMarilate;RARECHEM AL BI 0556;Ethyl 2-benzofurancarboxylate;ethyl benzofuran-2-carboxylate;Ethyl 1-benzofuran-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate;Ethyl benzo[b]furan-2-carboxylate 97%;BENZOFURAN-2-CARBOXLIC ACID ETHYL ESTER;BENZOFURAN-2-CARBOXYLIC ACID ETHYL ESTER;2-BENZOFURANCARBOXYLIC ACID, ETHYL ESTER
- CBNumber
- CB4414494
- Molecular Formula
- C11H10O3
- Formula Weight
- 190.2
- MOL File
- 3199-61-9.mol
2-Benzofurancarboxylic acid ethyl ester Property
- Melting point:
- 166-170℃
- Boiling point:
- 105°/0.1mm
- Density
- 1.1656
- refractive index
- 1.5640 (estimate)
- Flash point:
- >110℃
- storage temp.
- 2-8°C
- CAS DataBase Reference
- 3199-61-9(CAS DataBase Reference)
Safety
- Hazard Codes
- T
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2932190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 763632
- Product name
- Ethyl benzofuran-2-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $30.2
- Updated
- 2023/06/20
- Product number
- E904900
- Product name
- EthylCoumarilate
- Packaging
- 2.5g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- 2H23-1-X1
- Product name
- Ethylbenzo[b]furan-2-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $108
- Updated
- 2021/12/16
- Product number
- FB33202
- Product name
- Benzofuran-2-carboxylic acid ethyl ester
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- N531
- Product name
- Benzofuran-2-carboxylicacidethylester
- Packaging
- 10g
- Price
- $134
- Updated
- 2021/12/16
2-Benzofurancarboxylic acid ethyl ester Chemical Properties,Usage,Production
Uses
Ethyl Coumarilate has been used as a reactant for the preparation of benzofuropyridines that have a high affinity for the α2-adrenoceptor.
Preparation
Synthesis of ethyl benzofuran-2-carboxylate: Salicylaldehyde (20.0 mL, 0.164 mol) and diethyl bromomalonate (40.0 mL, 0.168 mol) in ethyl methyl ketone (40.0 mL, 0.555 mol) was treated with anhydrous potassium carbonate (20.0 g,0.869 mol). The reaction mixture was refluxed for 18 h on steam bath. Ethyl methyl ketone was distilled off under reduced pressure and the residue formed was dissolved in 400 mL of water and cooled in an ice-bath. It was acidified with dil H2SO4. The product formed was extracted with 25 mL portion of solvent ether twice and the extract was washed with sodium bicarbonate solution. It was dried over calcium chloride. Solvent was removed and the residue ethyl benzofuran-2-carboxylate was dried.
Synthesis Reference(s)
Tetrahedron Letters, 27, p. 6315, 1986 DOI: 10.1016/S0040-4039(00)87796-5
2-Benzofurancarboxylic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
2-Benzofurancarboxylic acid ethyl ester Suppliers
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- info@kaironkem.com
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- France
- ProdList
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View Lastest Price from 2-Benzofurancarboxylic acid ethyl ester manufacturers
- Product
- 2-Benzofurancarboxylic acid ethyl ester 3199-61-9
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-09
- Product
- 2-Benzofurancarboxylic acid ethyl ester 3199-61-9
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-09