URIDINE 5'-TRIPHOSPHATE TRIS SALT
- Product Name
- URIDINE 5'-TRIPHOSPHATE TRIS SALT
- CAS No.
- 108321-53-5
- Chemical Name
- URIDINE 5'-TRIPHOSPHATE TRIS SALT
- Synonyms
- UTP TRIS SALT;-triphosphatetrissalt;Uridine 5'-triphosphate (UTP);URIDINE 5'-TRIPHOSPHATE TRIS SALT;uridine 5'-triphosphate tris type vi
- CBNumber
- CB4418861
- Molecular Formula
- C13H26N3O18P3
- Formula Weight
- 605.28
- MOL File
- 108321-53-5.mol
URIDINE 5'-TRIPHOSPHATE TRIS SALT Property
- storage temp.
- -20°C
- solubility
- H2O: soluble50mg/mL, clear, colorless
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38
- Safety Statements
- 22-26-36-45
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- U6875
- Product name
- Uridine 5′-triphosphate tris salt
- Purity
- Type VI, ≥90%
- Packaging
- 100mg
- Price
- $171
- Updated
- 2024/03/01
- Product number
- U6875
- Product name
- Uridine 5′-triphosphate tris salt
- Purity
- Type VI, ≥90%
- Packaging
- 500mg
- Price
- $681
- Updated
- 2024/03/01
- Product number
- U830043
- Product name
- Uridine 5′-triphosphate tris salt
- Packaging
- 100mg
- Price
- $1200
- Updated
- 2021/12/16
- Product number
- NUC0002359
- Product name
- URIDINE-5'-TRIPHOSPHATE TRIS SALT
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1286.02
- Updated
- 2021/12/16
- Product number
- NUC0002359
- Product name
- URIDINE-5'-TRIPHOSPHATE TRIS SALT
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $731.89
- Updated
- 2021/12/16
URIDINE 5'-TRIPHOSPHATE TRIS SALT Chemical Properties,Usage,Production
Uses
Uridine 5''-Triphosphate Tris Salt is a polyphosphate analogue of the nucleoside Uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.
Uses
Uridine 5′-triphosphate tris salt has been used:
- to investigate its activation potential on the purinergic?P2Y2 Receptor in THP1 monocytes
- as a component of non-radioactive nucleoside triphosphate solution used in in vitro RNA polymerase assay
- as a P2Y2 agonist in human embryonic kidney cells (HEK293T) in dynamic mass redistribution (DMR) assays
Biochem/physiol Actions
Uridine 5′-triphosphate (UTP) is synthesized from uridine 5′-diphosphate (UDP) in the presence of the enzyme nucleoside diphosphate kinase (NDPK). Plant cells have high uridine as UTP. UTP on amination results in the generation of CTP and is catalysed by enzyme CTP synthetase. UTP acts on the purinergic?(P2Y2) receptor and mediates smooth muscle cells (SMCs) mitogenic activation. It also modulates osteopontin expression in SMCs. UTP is a sputum inducer and a promising candidate for assessing the inflammation in respiratory airway.