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Copper(II) gluconate

Description References
Product Name
Copper(II) gluconate
CAS No.
527-09-3
Chemical Name
Copper(II) gluconate
Synonyms
COPPER GLUCONATE;CUPRIC GLUCONATE;copper di-D-gluconate;Copper(II) glucote;COPPERGLUCONATE,FCC;COPPERGLUCONATE,USP;Glucose acid copper;COPPER(II) GLUCONATE;D-Gluconic acid copp;COPPER(+2)D-GLUCONATE
CBNumber
CB4437183
Molecular Formula
C12H22CuO14
Formula Weight
453.84
MOL File
527-09-3.mol
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Copper(II) gluconate Property

Melting point:
155-157 °C(lit.)
Boiling point:
673.6℃[at 101 325 Pa]
Density 
1.777[at 20℃]
vapor pressure 
13.3Pa at 20℃
refractive index 
16.5 ° (C=1, H2O)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Aqueous Acid (Slightly), Water (Sparingly, Sonicated)
form 
powder
color 
Light Blue to Blue
optical activity
[α]26/D +15°, c = 1 in H2O
Water Solubility 
slightly soluble
Merck 
14,2640
Exposure limits
ACGIH: TWA 1 mg/m3
NIOSH: IDLH 100 mg/m3; TWA 1 mg/m3
Stability:
Hygrscopic
LogP
-2.98
CAS DataBase Reference
527-09-3(CAS DataBase Reference)
EPA Substance Registry System
Copper gluconate (527-09-3)
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LZ5058000
TSCA 
Yes
HS Code 
29181600
Hazardous Substances Data
527-09-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
344419
Product name
Copper(II) D-gluconate
Purity
98%
Packaging
100g
Price
$63.8
Updated
2025/07/31
TCI Chemical
Product number
G0275
Product name
Copper(II) Gluconate
Purity
>97.0%(T)
Packaging
25g
Price
$26
Updated
2025/07/31
TCI Chemical
Product number
G0275
Product name
Copper(II) Gluconate
Purity
>97.0%(T)
Packaging
100g
Price
$71
Updated
2025/07/31
TRC
Product number
C685435
Product name
Copper(II) gluconate
Packaging
5g
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
MG07603
Product name
D-Gluconic acid copper (II) salt
Packaging
5kg
Price
$375
Updated
2021/12/16
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Copper(II) gluconate Chemical Properties,Usage,Production

Description

Copper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram.

References

Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.

Chemical Properties

Copper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol.

Uses

copper gluconate is cited as having skin-conditioning and skinprotecting functions.

Uses

Supplement (trace mineral).

Uses

Copper(II) gluconate is used in dietary supplement. It is also used to treat acne vulgaris, common cold, hypertension, premature labor, leishmaniasis and visceral postoperative complications. Further, it is used in oral deodorants and feed additives. In addition to this, it is used as a synergist and nutritional supplement for foods. It is the active component in retsyn used in mints and certs.

Definition

ChEBI: Copper gluconate is an organic molecular entity.

Preparation

Copper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants.

Flammability and Explosibility

Not classified

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

Copper(II) gluconate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Copper(II) gluconate manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.
Product
Copper Gluconate 527-09-3
Price
US $1200.00-1100.00/ton
Min. Order
1ton
Purity
99%
Supply Ability
1000T/M
Release date
2025-09-15
Hebei Fengjia New Material Co., Ltd
Product
Copper(II) gluconate 527-09-3
Price
US $30.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100 tons
Release date
2024-08-14
Hebei Chuanghai Biotechnology Co., Ltd
Product
Copper Gluconate 527-09-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-28

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  • C12H22CuO14
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  • HOCH2CHOH4CO22Cu
  • C6H11O7紺u
  • 2C6H11O7Cu
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