5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE
- Product Name
- 5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE
- CAS No.
- 53525-65-8
- Chemical Name
- 5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE
- Synonyms
- SPECS AN-584/43226970;Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione;Diimidazo[1,5-a:1’,5’-d)pyrazine-5,10-dione,HCl;5H,10H-diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione;Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione, DiHCl;5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE;5H,10H-DiiMidazo[1,5-a:1', 5'-d] pyrazine-5,10-dione b;5H,10H-Diimidazo[1,5-A:1', 5'-D] pyrazine-5,10-dione ,98%;Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione, dihydrochloride
- CBNumber
- CB4438599
- Molecular Formula
- C8H4N4O2
- Formula Weight
- 188.14
- MOL File
- 53525-65-8.mol
5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE Property
- storage temp.
- 2-8°C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P330Rinse mouth.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D680050
- Product name
- 5H,10H-Diimidazo[1,5-A:1'',5''-D]pyrazine-5,10-dione
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- V6475
- Product name
- Diimidazo[1,5-a:1'',5''-d]pyrazine-5,10-dioneDiHCl
- Packaging
- 5g
- Price
- $1230
- Updated
- 2021/12/16
- Product number
- CHM0029240
- Product name
- DIIMIDAZO[1,5-A:1',5'-D]PYRAZINE-5,10-DIONE
- Purity
- 95.00%
- Packaging
- 1KG
- Price
- $11896.5
- Updated
- 2021/12/16
- Product number
- A159530
- Product name
- Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione
- Purity
- 95%
- Packaging
- 100mg
- Price
- $42
- Updated
- 2021/12/16
- Product number
- CD11109219
- Product name
- Diimidazo[1,5-a:1',5'-d]pyrazine-5,10-dione
- Purity
- 95+%
- Packaging
- 25g
- Price
- $1980
- Updated
- 2021/12/16
5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE Chemical Properties,Usage,Production
Synthesis
1072-84-0
53525-65-8
General procedure for the synthesis of imidazo[1,5-a:1',5'-d]pyrazine-5,10-dione from 1H-imidazole-4-carboxylic acid: 1H-imidazole-4-carboxylic acid (5 g, 44.6 mmol) was suspended in thionyl chloride (75 mL), and heated and refluxed under stirring for 18 hours. After completion of the reaction, the reaction mixture was cooled, filtered, washed with toluene and dried under high vacuum to afford the target compound imidazo[1,5-a:1',5'-d]pyrazine-5,10-dione as a yellow solid in 95% yield. Molecular formula: C8H4N4O2, molecular weight: 188.14 g/mol, melting point: 265-268°C. 1H NMR (300 MHz, DMSO-d6) δ: 8.24 (d, 1H, CHC-CO), 8.32 (d, 1H, CHC-CO, J=3Hz), 8.88 (d, 1H, CHN), 9.28 (d, 1H , CHN, J=3Hz).13C NMR (100 MHz, DMSO-d6) δ: 123.99, 124.52, 125.62, 137.26, 139.73, 150.39, 159.68.MS (ESI+, QTof, m/z): 189.0 [M + H]+.
References
[1] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 13, p. 6601 - 6610
[2] European Journal of Medicinal Chemistry, 2017, vol. 138, p. 909 - 919
[3] Pharmaceutical Chemistry Journal, 1986, vol. 20, # 7, p. 460 - 463
[4] Khimiko-Farmatsevticheskii Zhurnal, 1986, vol. 20, # 7, p. 799 - 802
[5] Patent: EP1439169, 2004, A1. Location in patent: Page 81-82
5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE Preparation Products And Raw materials
Raw materials
Preparation Products
5H,10H-DIIMIDAZO[1,5-A:1', 5'-D] PYRAZINE-5,10-DIONE Suppliers
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