FTI-276

Product Name: FTI-276
CAS No.: 170006-72-1
Chemical Name: FTI-276
Synonyms: FTI-276;ZIXDDEATQSBHHL-BEFAXECRSA-N;FTI-276 trifluoroacetate salt;N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-;N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT
CBNumber: CB4442484
Molecular Formula: C21H27N3O3S2
Formula Weight: 433.59
MOL File: Mol file

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FTI-276 Property

Boiling point:: 715.6±60.0 °C(Predicted)
Density: 1.272±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: H₂O: >5 mg/mL, soluble
pka: 3.54±0.10(Predicted)
form: solid
color: off-white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 344550
Product name: FTI-276
Purity: A highly potent and selective CAAX peptidomimetic of the carboxyl terminal of Ras proteins that inhibits farnesyl transferase (FTase) in vitro (IC?? = 500 pM).
Packaging: 250μG
Price: $245
Updated: 2024/03/01

Usbiological

Product number: 255340
Product name: FTI 276
Packaging: 1mg
Price: $389
Updated: 2021/12/16

ChemScene

Product number: CS-0009428
Product name: FTI276
Packaging: 5mg
Price: $400
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0066839
Product name: FTI-276 TRIFLUOROACETATE SALT
Purity: 95.00%
Packaging: 1MG
Price: $676.71
Updated: 2021/12/16

ChemScene

Product number: CS-0009428
Product name: FTI276
Packaging: 10mg
Price: $680
Updated: 2021/12/16

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FTI-276 Chemical Properties,Usage,Production

Uses

N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine Trifluoroacetate Salt is a useful intermediate.

Definition

ChEBI: (2S)-2-[[[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-phenylphenyl]-oxomethyl]amino]-4-(methylthio)butanoic acid is a methionine derivative.

Biochem/physiol Actions

FTI-276 is a highly potent RasCAAX peptidomimetic. FTI-276 antagonizes both H and K-Ras oncogenic signaling. It is an inhibitor of farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM and is an anti-cancer agent.

FTI-276 Preparation Products And Raw materials

Raw materials

Preparation Products

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FTI-276 Suppliers

China 30 Japan 2 Switzerland 1 United Kingdom 2 United States 9 Global 44

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52849
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9266
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19885
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49978
Advantage: 58

170006-72-1, FTI-276Related Search:

N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT

N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA

FTI-276

FTI-276 trifluoroacetate salt

ZIXDDEATQSBHHL-BEFAXECRSA-N

L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-

170006-72-1

C21H27N3O3S2C2HF3O2

C23H28F3N3O5S2