ChemicalBook > CAS DataBase List > FTI-276
FTI-276
- Product Name
- FTI-276
- CAS No.
- 170006-72-1
- Chemical Name
- FTI-276
- Synonyms
- FTI-276;ZIXDDEATQSBHHL-BEFAXECRSA-N;FTI-276 trifluoroacetate salt;N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-;N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT
- CBNumber
- CB4442484
- Molecular Formula
- C21H27N3O3S2
- Formula Weight
- 433.59
- MOL File
- Mol file
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FTI-276 Property
- Boiling point:
- 715.6±60.0 °C(Predicted)
- Density
- 1.272±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- H2O: >5 mg/mL, soluble
- pka
- 3.54±0.10(Predicted)
- form
- solid
- color
- off-white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 344550
- Product name
- FTI-276
- Purity
- A highly potent and selective CAAX peptidomimetic of the carboxyl terminal of Ras proteins that inhibits farnesyl transferase (FTase) in vitro (IC?? = 500 pM).
- Packaging
- 250μG
- Price
- $245
- Updated
- 2024/03/01
Usbiological
- Product number
- 255340
- Product name
- FTI 276
- Packaging
- 1mg
- Price
- $389
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0009428
- Product name
- FTI276
- Packaging
- 5mg
- Price
- $400
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0066839
- Product name
- FTI-276 TRIFLUOROACETATE SALT
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $676.71
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0009428
- Product name
- FTI276
- Packaging
- 10mg
- Price
- $680
- Updated
- 2021/12/16
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FTI-276 Chemical Properties,Usage,Production
Uses
N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine Trifluoroacetate Salt is a useful intermediate.
Definition
ChEBI: (2S)-2-[[[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-phenylphenyl]-oxomethyl]amino]-4-(methylthio)butanoic acid is a methionine derivative.
Biochem/physiol Actions
FTI-276 is a highly potent RasCAAX peptidomimetic. FTI-276 antagonizes both H and K-Ras oncogenic signaling. It is an inhibitor of farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM and is an anti-cancer agent.
FTI-276 Preparation Products And Raw materials
Raw materials
Preparation Products
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FTI-276 Suppliers
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- 821-50328103-801 18930552037
- Fax
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- China
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