4-(BENZYLOXY)PYRIDINE
- Product Name
- 4-(BENZYLOXY)PYRIDINE
- CAS No.
- 49826-70-2
- Chemical Name
- 4-(BENZYLOXY)PYRIDINE
- Synonyms
- 4-(BENZYLOXY)PYRIDINE;4-BENZYLOXYPYRIDINE(I);4-phenylmethoxypyridine;Pyridine,4-(phenylmethoxy)-;4-[(Phenylmethyl)oxy]pyridine;ETHYL3-(CYANOMETHYL)-2-OXO-2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE-3-CARBOXYLATE
- CBNumber
- CB4445829
- Molecular Formula
- C12H11NO
- Formula Weight
- 185.22
- MOL File
- 49826-70-2.mol
4-(BENZYLOXY)PYRIDINE Property
- Melting point:
- 57-58℃
- Boiling point:
- 310℃
- Density
- 1.106
- Flash point:
- 114℃
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 6.58±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR942402
- Product name
- 4-(Benzyloxy)pyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $203
- Updated
- 2021/12/16
- Product number
- OR942402
- Product name
- 4-(Benzyloxy)pyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $486
- Updated
- 2021/12/16
- Product number
- CHM0378179
- Product name
- 4-(BENZYLOXY)PYRIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.16
- Updated
- 2021/12/16
- Product number
- 2549AL
- Product name
- 4-(Benzyloxy)pyridine
- Packaging
- 5g
- Price
- $840
- Updated
- 2021/12/16
- Product number
- 2549AL
- Product name
- 4-(Benzyloxy)pyridine
- Packaging
- 10g
- Price
- $1245
- Updated
- 2021/12/16
4-(BENZYLOXY)PYRIDINE Chemical Properties,Usage,Production
Synthesis
7379-35-3
100-51-6
49826-70-2
Sodium hydride (60% mineral oil dispersion, 0.72 g, 18.0 mmol) was added to a dry reaction flask, followed by the addition of N,N-dimethylformamide (30 mL) to form a suspension, and the mixture was cooled to 5 °C. Under stirring, benzyl alcohol (1.04 mL, 10.0 mmol) was slowly added dropwise. After dropwise addition, stirring was continued for 15 minutes. Subsequently, 4-chloropyridine hydrochloride (1.00 g, 6.67 mmol) was added in batches, with each addition approximately 5 minutes apart. After the addition was completed, the reaction mixture was stirred at 5°C for 10 minutes, then gradually warmed to 60°C and stirred at this temperature for 1.5 hours. After completion of the reaction, the mixture was cooled to room temperature (23°C), the reaction was quenched by the addition of water and extracted with ethyl acetate. The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with gradient elution of hexane solution with 5% to 50% ethyl acetate as eluent to give the target product 4-benzyloxypyridine (1.10 g, 89% yield).
References
[1] Journal of Organic Chemistry, 2017, vol. 82, # 24, p. 13756 - 13767
[2] Patent: US2011/275627, 2011, A1. Location in patent: Page/Page column 60
[3] Patent: EP2331541, 2011, A1. Location in patent: Paragraph 0070; 0071
[4] Patent: EP2331541, 2015, B1. Location in patent: Paragraph 0070; 0071
4-(BENZYLOXY)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-(BENZYLOXY)PYRIDINE Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 4-(BENZYLOXY)PYRIDINE manufacturers
- Product
- 4-(BENZYLOXY)PYRIDINE 49826-70-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-26
- Product
- 4-phenylmethoxypyridine 49826-70-2
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09