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N1-ACETYLSPERMINE TRIHYDROCHLORIDE

Product Name
N1-ACETYLSPERMINE TRIHYDROCHLORIDE
CAS No.
77928-70-2
Chemical Name
N1-ACETYLSPERMINE TRIHYDROCHLORIDE
Synonyms
N1-Acetylspermine (hydrochloride);1-ACETYLSPERMINE TRIHYDROCHLORIDE;N1-ACETYLSPERMINE TRIHYDROCHLORIDE;N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)acetamide trihydrochloride
CBNumber
CB4446457
Molecular Formula
C12H31Cl3N4O
Formula Weight
353.76
MOL File
77928-70-2.mol
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N1-ACETYLSPERMINE TRIHYDROCHLORIDE Property

Melting point:
>256°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
BRN 
7052482
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
01467
Product name
N1-Acetylspermine trihydrochloride
Purity
≥97.0% (TLC)
Packaging
25mg
Price
$71.6
Updated
2024/03/01
Sigma-Aldrich
Product number
01467
Product name
N1-Acetylspermine trihydrochloride
Purity
≥97.0% (TLC)
Packaging
100mg
Price
$229
Updated
2024/03/01
Cayman Chemical
Product number
17919
Product name
N1-Acetylspermine (hydrochloride)
Purity
≥95%
Packaging
25mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
17919
Product name
N1-Acetylspermine (hydrochloride)
Purity
≥95%
Packaging
50mg
Price
$115
Updated
2024/03/01
TRC
Product number
A188005
Product name
N1-Acetylspermine trihydrochloride
Packaging
2.5mg
Price
$180
Updated
2021/12/16
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N1-ACETYLSPERMINE TRIHYDROCHLORIDE Chemical Properties,Usage,Production

Description

N1-Acetylspermine is a monoacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. N1-Acetylspermine has been used to study the uptake of the anticancer polyamine analog bleomycin-A5 by the human carnitine transporter SLC22A16.

Uses

N1-Acetylspermine trihydrochloride has been used in a study to determine that the human carnitine transporter SLC22A16 mediates high affinity uptake of the anticancer polyamine analogue bleomycin-A5.

N1-ACETYLSPERMINE TRIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N1-ACETYLSPERMINE TRIHYDROCHLORIDE Suppliers

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77928-70-2, N1-ACETYLSPERMINE TRIHYDROCHLORIDERelated Search:

Spermidine N-(4-HYDROXYPHENYLPROPANOYL) SPERMINE TRIHYDROCHLORIDE N8-ACETYLSPERMIDINE DIHYDROCHLORIDE N1-ACETYLSPERMINE TRIHYDROCHLORIDE Spermidine trihydrochloride SPERMINEHYDROCHLORIDE 1-NAPHTHYLACETYL SPERMINE TRIHYDROCHLORIDE Dipentene

  • N1-ACETYLSPERMINE TRIHYDROCHLORIDE
  • 1-ACETYLSPERMINE TRIHYDROCHLORIDE
  • N1-Acetylspermine (hydrochloride)
  • N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)acetamide trihydrochloride
  • 77928-70-2
  • C12H31Cl3N4O
  • C12H28N4O3HCl