N1-ACETYLSPERMINE TRIHYDROCHLORIDE
- Product Name
- N1-ACETYLSPERMINE TRIHYDROCHLORIDE
- CAS No.
- 77928-70-2
- Chemical Name
- N1-ACETYLSPERMINE TRIHYDROCHLORIDE
- Synonyms
- N1-Acetylspermine (hydrochloride);1-ACETYLSPERMINE TRIHYDROCHLORIDE;N1-ACETYLSPERMINE TRIHYDROCHLORIDE;N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)acetamide trihydrochloride
- CBNumber
- CB4446457
- Molecular Formula
- C12H31Cl3N4O
- Formula Weight
- 353.76
- MOL File
- 77928-70-2.mol
N1-ACETYLSPERMINE TRIHYDROCHLORIDE Property
- Melting point:
- >256°C (dec.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- BRN
- 7052482
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 01467
- Product name
- N1-Acetylspermine trihydrochloride
- Purity
- ≥97.0% (TLC)
- Packaging
- 25mg
- Price
- $71.6
- Updated
- 2024/03/01
- Product number
- 01467
- Product name
- N1-Acetylspermine trihydrochloride
- Purity
- ≥97.0% (TLC)
- Packaging
- 100mg
- Price
- $229
- Updated
- 2024/03/01
- Product number
- 17919
- Product name
- N1-Acetylspermine (hydrochloride)
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 17919
- Product name
- N1-Acetylspermine (hydrochloride)
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- A188005
- Product name
- N1-Acetylspermine trihydrochloride
- Packaging
- 2.5mg
- Price
- $180
- Updated
- 2021/12/16
N1-ACETYLSPERMINE TRIHYDROCHLORIDE Chemical Properties,Usage,Production
Description
N1-Acetylspermine is a monoacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. N1-Acetylspermine has been used to study the uptake of the anticancer polyamine analog bleomycin-A5 by the human carnitine transporter SLC22A16.
Uses
N1-Acetylspermine trihydrochloride has been used in a study to determine that the human carnitine transporter SLC22A16 mediates high affinity uptake of the anticancer polyamine analogue bleomycin-A5.