PHT-ALA-OH
- Product Name
- PHT-ALA-OH
- CAS No.
- 4192-28-3
- Chemical Name
- PHT-ALA-OH
- Synonyms
- Pht-Ala;Pht-L-Ala;PHT-ALA-OH;N-Pht-L-Ala;Pht-L-Ala-OH;Phth-L-Ala-OH;PHTHALYL-L-ALANINE;PHTHALOYL-L-ALANINE;N-PHTHALYL-L-ALANINE;PHT-ALA-OH USP/EP/BP
- CBNumber
- CB4447838
- Molecular Formula
- C11H9NO4
- Formula Weight
- 219.19
- MOL File
- 4192-28-3.mol
PHT-ALA-OH Property
- Melting point:
- 139 - 141°C
- Boiling point:
- 407.9±28.0 °C(Predicted)
- Density
- 1.467±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- pka
- 3?+-.0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1/C11H9NO4/c1-6(11(15)16)12-9(13)7-4-2-3-5-8(7)10(12)14/h2-6H,1H3,(H,15,16)/t6-/s3
- InChIKey
- OZWUITKBAWTEAQ-ISZMHOAENA-N
- SMILES
- N1([C@@H](C)C(=O)O)C(=O)C2C=CC=CC=2C1=O |&1:1,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P3224
- Product name
- Pht-Ala-OH
- Packaging
- 25G
- Price
- $137
- Updated
- 2025/07/31
- Product number
- P3224
- Product name
- Pht-Ala-OH
- Packaging
- 100G
- Price
- $342
- Updated
- 2025/07/31
- Product number
- P840148
- Product name
- Pht-Ala-OH
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 241263
- Product name
- Phthaloyl-L-alanine
- Packaging
- 5g
- Price
- $245
- Updated
- 2021/12/16
- Product number
- 287226
- Product name
- Phthaloyl-L-alanine
- Packaging
- 5g
- Price
- $375
- Updated
- 2021/12/16
PHT-ALA-OH Chemical Properties,Usage,Production
Chemical Properties
White crystals
Synthesis
56-41-7
22509-74-6
4192-28-3
The general procedure for the synthesis of phthaloyl-L-alanine from L-alanine and N-ethoxycarbonylphthalimide was as follows: to a stirred aqueous solution (100 mL) of L-alanine (8.9 g, 100.00 mmol) and Na2CO3 (10.6 g, 100.00 mmol) was added slowly N-ethoxycarbonylphthalimide. After the reaction for 1.5 h, the reaction mixture was slowly acidified to pH = 1-2 with aqueous 1N HCl. The precipitate was collected by filtration to afford a white solid phthaloyl-L-alanine 17.37 g in 79.3% yield. The melting point of the product was 145.8-146.6 °C. 1H NMR (CDCl3, 400 MHz) δ: 1.71 (s, 3H, CH3), 5.02 (q, J = 7.4 Hz, 1H, CH), 7.69-7.75 (m, 2H, Ar-H), 7.82-7.88 (m, 2H, Ar-H). mS (ESI): m/z 218.2 [M+H]+.
References
[1] Angewandte Chemie - International Edition, 2013, vol. 52, # 51, p. 13588 - 13592
[2] Angew. Chem., 2013, vol. 125, # 51, p. 13833 - 13837,5
[3] Chemical Communications, 2017, vol. 53, # 47, p. 6351 - 6354
[4] Synthetic Communications, 1983, vol. 13, # 4, p. 311 - 318
[5] Synthetic Communications, 1983, vol. 13, # 5, p. 393 - 402
PHT-ALA-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PHT-ALA-OH manufacturers
- Product
- PHT-ALA-OH 4192-28-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-22
- Product
- (S)-2-(1,3-Dioxoisoindolin-2-yl)propanoic acid 4192-28-3
- Price
- US $1.00-35.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-07-30
- Product
- PHT-ALA-OH 4192-28-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-18