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PHT-ALA-OH

Product Name
PHT-ALA-OH
CAS No.
4192-28-3
Chemical Name
PHT-ALA-OH
Synonyms
Pht-Ala;Pht-L-Ala;PHT-ALA-OH;N-Pht-L-Ala;Pht-L-Ala-OH;Phth-L-Ala-OH;PHTHALYL-L-ALANINE;PHTHALOYL-L-ALANINE;N-PHTHALYL-L-ALANINE;PHT-ALA-OH USP/EP/BP
CBNumber
CB4447838
Molecular Formula
C11H9NO4
Formula Weight
219.19
MOL File
4192-28-3.mol
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PHT-ALA-OH Property

Melting point:
139 - 141°C
Boiling point:
407.9±28.0 °C(Predicted)
Density 
1.467±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
pka
3?+-.0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1/C11H9NO4/c1-6(11(15)16)12-9(13)7-4-2-3-5-8(7)10(12)14/h2-6H,1H3,(H,15,16)/t6-/s3
InChIKey
OZWUITKBAWTEAQ-ISZMHOAENA-N
SMILES
N1([C@@H](C)C(=O)O)C(=O)C2C=CC=CC=2C1=O |&1:1,r|
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
P3224
Product name
Pht-Ala-OH
Packaging
25G
Price
$137
Updated
2025/07/31
TCI Chemical
Product number
P3224
Product name
Pht-Ala-OH
Packaging
100G
Price
$342
Updated
2025/07/31
TRC
Product number
P840148
Product name
Pht-Ala-OH
Packaging
500mg
Price
$60
Updated
2021/12/16
Usbiological
Product number
241263
Product name
Phthaloyl-L-alanine
Packaging
5g
Price
$245
Updated
2021/12/16
Usbiological
Product number
287226
Product name
Phthaloyl-L-alanine
Packaging
5g
Price
$375
Updated
2021/12/16
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PHT-ALA-OH Chemical Properties,Usage,Production

Chemical Properties

White crystals

Synthesis

56-41-7

22509-74-6

4192-28-3

The general procedure for the synthesis of phthaloyl-L-alanine from L-alanine and N-ethoxycarbonylphthalimide was as follows: to a stirred aqueous solution (100 mL) of L-alanine (8.9 g, 100.00 mmol) and Na2CO3 (10.6 g, 100.00 mmol) was added slowly N-ethoxycarbonylphthalimide. After the reaction for 1.5 h, the reaction mixture was slowly acidified to pH = 1-2 with aqueous 1N HCl. The precipitate was collected by filtration to afford a white solid phthaloyl-L-alanine 17.37 g in 79.3% yield. The melting point of the product was 145.8-146.6 °C. 1H NMR (CDCl3, 400 MHz) δ: 1.71 (s, 3H, CH3), 5.02 (q, J = 7.4 Hz, 1H, CH), 7.69-7.75 (m, 2H, Ar-H), 7.82-7.88 (m, 2H, Ar-H). mS (ESI): m/z 218.2 [M+H]+.

References

[1] Angewandte Chemie - International Edition, 2013, vol. 52, # 51, p. 13588 - 13592
[2] Angew. Chem., 2013, vol. 125, # 51, p. 13833 - 13837,5
[3] Chemical Communications, 2017, vol. 53, # 47, p. 6351 - 6354
[4] Synthetic Communications, 1983, vol. 13, # 4, p. 311 - 318
[5] Synthetic Communications, 1983, vol. 13, # 5, p. 393 - 402

PHT-ALA-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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PHT-ALA-OH Suppliers

Hefei QiChang Biological Technology Co., Ltd.
Tel
18019964904; 17756579152
Fax
QQ:252833506
Email
liuchun.0228@163.com
Country
China
ProdList
64
Advantage
58
Yangzhou Aoxin Chemical Co., Ltd
Tel
0514-87754778 13901446058
Fax
+86-514-87752291
Email
sales@aochem.com
Country
China
ProdList
73
Advantage
66
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19906
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39967
Advantage
60
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View Lastest Price from PHT-ALA-OH manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
PHT-ALA-OH 4192-28-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-22
Shaanxi Dideu Medichem Co. Ltd
Product
(S)-2-(1,3-Dioxoisoindolin-2-yl)propanoic acid 4192-28-3
Price
US $1.00-35.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2024-07-30
Career Henan Chemical Co
Product
PHT-ALA-OH 4192-28-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-18

4192-28-3, PHT-ALA-OHRelated Search:


  • N-PHTHALOYL-L-ALANINE
  • N-PHTHALYL-L-ALANINE
  • PHTHALOYL-L-ALANINE
  • PHTHALYL-L-ALANINE
  • PHT-ALA-OH
  • (2S)-2-(1,3-Dioxo-2H-isoindole-2-yl)propionic acid
  • (S)-2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol)-2-yl]propanoic acid
  • (S)-N,N-Phthaloylalanine
  • (S)-α-Methyl-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid
  • (αS)-α-Methyl-1,3-dioxoisoindoline-2-acetic acid
  • N,N-Phthaloyl-L-alanine
  • (S)-2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)propionylic acid
  • (S)-2-(1,3-Dioxoisoindolin-2-yl)propanoic acid
  • Phth-L-Ala-OH
  • Pht-L-Ala-OH
  • (2S)-2-(1,3-dioxoisoindol-2-yl)propanoic acid
  • Phthaloyl-L-alanine99%
  • Pht-L-Ala
  • Amino Acid Impurity 37
  • Pht-Ala
  • 2H-Isoindole-2-acetic acid, 1,3-dihydro-α-methyl-1,3-dioxo-, (αS)-
  • (2S)-2-(1,3-dioxoisoindol-2-yl)propanoicaci
  • PHT-ALA-OH USP/EP/BP
  • N-Pht-L-Ala
  • 4192-28-3