D-Alanine Methyl Ester Hydrochloride
- Product Name
- D-Alanine Methyl Ester Hydrochloride
- CAS No.
- 14316-06-4
- Chemical Name
- D-Alanine Methyl Ester Hydrochloride
- Synonyms
- METHYL D-ALANINATE HYDROCHLORIDE;D-ALANINE METHYL ESTER HCL;(R)-Methyl 2-aminopropanoate hydrochloride;D-Alanina;Nsc523192;D-Ala-OMe HCl;H-D-ALA-OME HCL;D-ALANINE-OME HCL;Acetyl Bromide LR;D-Alanine Methyl Est
- CBNumber
- CB1742495
- Molecular Formula
- C4H10ClNO2
- Formula Weight
- 139.58
- MOL File
- 14316-06-4.mol
D-Alanine Methyl Ester Hydrochloride Property
- Melting point:
- 108-110 °C(lit.)
- alpha
- -8 º (c=1.6, MeOH)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Sparingly), Methanol (Sparingly), Water (Slightly)
- form
- Crystalline Powder
- color
- White to off-white
- optical activity
- [α]20/D 8.0°, c = 1.6 in methanol
- Water Solubility
- Soluble in Water 100 mg/ml.
- InChI
- InChI=1/C4H9NO2.ClH/c1-3(5)4(6)7-2;/h3H,5H2,1-2H3;1H/t3-;/s3
- InChIKey
- IYUKFAFDFHZKPI-DFWYDOINSA-N
- SMILES
- C(OC)(=O)[C@@H](C)N.[H]Cl |&1:4,r|
- CAS DataBase Reference
- 14316-06-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 414549
- Product name
- D-Alanine methyl ester hydrochloride
- Purity
- 98%
- Packaging
- 5g
- Price
- $53.06
- Updated
- 2025/07/31
- Product number
- 414549
- Product name
- D-Alanine methyl ester hydrochloride
- Purity
- 98%
- Packaging
- 25g
- Price
- $97.3
- Updated
- 2025/07/31
- Product number
- A2011
- Product name
- D-Alanine Methyl Ester Hydrochloride
- Purity
- >97.0%(N)(T)
- Packaging
- 5g
- Price
- $30
- Updated
- 2025/07/31
- Product number
- A2011
- Product name
- D-Alanine Methyl Ester Hydrochloride
- Purity
- >97.0%(N)(T)
- Packaging
- 25g
- Price
- $103
- Updated
- 2025/07/31
- Product number
- 237097
- Product name
- D-Alanine methyl ester hydrochloride 98+%
- Packaging
- 5g
- Price
- $159
- Updated
- 2021/12/16
D-Alanine Methyl Ester Hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
D-Alanine methyl ester hydrochloride is used as building block for the preparation of peptides.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
67-56-1
338-69-2
14316-06-4
GENERAL PROCEDURE: Thionyl chloride (SOCl?, 21.8 mL, 0.3 mol) and (S)-alanine (8.91 g, 0.1 mol) were added sequentially to methanol (CH?OH, 100 mL), and the reaction was stirred for 2 hours at room temperature. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in methanol (30 mL) and again distilled under reduced pressure to remove the organic solvent. This dissolution-distillation process was repeated twice. The final colorless amorphous solid product, D-alanine methyl ester hydrochloride, was obtained with a melting point of 103 °C (literature value 98-99 °C) and a yield of 14.3 g (yield >99%).
References
[1] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 17, p. 4778 - 4799
[2] Organic Preparations and Procedures International, 2002, vol. 34, # 1, p. 87 - 94
[3] Tetrahedron Letters, 1989, vol. 30, # 3, p. 313 - 316
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 15, p. 6293 - 6305
[5] European Journal of Organic Chemistry, 2010, # 22, p. 4276 - 4287
D-Alanine Methyl Ester Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
D-Alanine Methyl Ester Hydrochloride Suppliers
- Tel
- 0513-0513-0513-89158300 18014392889
- Fax
- 0513-89158198
- sales@puyerbiopharma.com
- Country
- China
- ProdList
- 4956
- Advantage
- 58
- Tel
- 021-50182298 021-50180596
- Fax
- +86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2208
- Advantage
- 55
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 21-61263452 13641803416
- Fax
- 86-21-61263399
- ymbetter@glbiochem.com
- Country
- China
- ProdList
- 9981
- Advantage
- 64
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
View Lastest Price from D-Alanine Methyl Ester Hydrochloride manufacturers
- Product
- D-Alanine Methyl Ester Hydrochloride 14316-06-4
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500kg
- Release date
- 2021-08-24
- Product
- D-Alanine Methyl Ester Hydrochloride 14316-06-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-13
- Product
- D-Ala-Ome.Hcl 14316-06-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-02-28