EC 2.6.1.2
Description Source Background- Product Name
- EC 2.6.1.2
- CAS No.
- 9000-86-6
- Chemical Name
- EC 2.6.1.2
- Synonyms
- GPT;AAT1;ALT1;GPT1;GPT/ALT;EC 2.6.1.2;GPT, HUMAN;TRANSAMINASE;EC 2.6.1.2 USP/EP/BP;ALANINE AMINOTRANSFERASE
- CBNumber
- CB3708727
- Molecular Formula
- C11H16N2O6
- Formula Weight
- 272.25454
- MOL File
- 9000-86-6.mol
EC 2.6.1.2 Property
- storage temp.
- -70°C
- form
- suspension (aqueous)
- color
- green-yellow
- biological source
- Porcine heart
- Water Solubility
- Dissolves readily at 5 mg/ml in 0.05M potassium phosphate pH 7.5 to give a clear, pale-green solution. Soluble in distilled water or dilute buffer.
- BRN
- 3562140
- Specific Activity
- ≥75units/mg protein
- InChI
- InChI=1S/C11H16N2O6/c1-5-3-13(11(18)12-10(5)17)8-2-6(15)9(16)7(4-14)19-8/h3,6-9,14-16H,2,4H2,1H3,(H,12,17,18)
- InChIKey
- VVJYUAYZJAKGRQ-UHFFFAOYSA-N
- SMILES
- C1(=O)N(C2CC(O)C(O)C(CO)O2)C=C(C)C(=O)N1
- EPA Substance Registry System
- Aminotransferase, alanine (9000-86-6)
Safety
- WGK Germany
- 3
- F
- 10
- TSCA
- Yes
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P284Wear respiratory protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T7684
- Product name
- Transaminase, broad-range bacterial
- Purity
- recombinant, expressed in <I>E. coli</I>, lyophilized powder, ≥5 units/mg solid
- Packaging
- 10 mg
- Price
- $682
- Updated
- 2025/07/31
- Product number
- G9880
- Product name
- Glutamic-Pyruvic Transaminase from porcine heart
- Purity
- ammonium sulfate suspension, ≥75?units/mg protein
- Packaging
- 500units
- Price
- $388
- Updated
- 2025/07/31
- Product number
- SAB1412234
- Product name
- ANTI-GPT antibody produced in mouse
- Purity
- clone M1, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100 μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- G8255
- Product name
- Glutamic-Pyruvic Transaminase from porcine heart
- Purity
- lyophilized powder, ≥75?units/mg protein
- Packaging
- 200units
- Price
- $143
- Updated
- 2025/07/31
- Product number
- G9880
- Product name
- Glutamic-Pyruvic Transaminase from porcine heart
- Purity
- ammonium sulfate suspension, ≥75?units/mg protein
- Packaging
- 1000units
- Price
- $644
- Updated
- 2025/07/31
EC 2.6.1.2 Chemical Properties,Usage,Production
Uses
It is used for research and clinical diagnostic assays for liver disease. Alanine transaminase (GPT/ALT) is used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers. The alanine aminotransferase (ALT) blood test is typically used to detect liver injury. Some of the other applications include Diagnostic Controls, calibrators & standards, immunoassays, clinical chemistry, testing/assay validation, life Science, manufacturing, validation Studies.
General Description
Glutamic-pyruvic transaminase (GPT) is localized majorly in the liver.
Biochem/physiol Actions
Glutamic-pyruvic transaminase (GPT) mediates the transfer of the amino group to α-ketoglutarate from l-alanine. It plays a key role in gluconeogenesis and amino acid metabolism. The role of GPT in various kinds of tumors has been reported.
Description
GPT Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 516 amino acids (1-496) and having a molecular mass of 56.8 kDa.
GPT is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Ecoli
Background
GPT catalyzes the reversible transamination between alanine and 2-oxoglutarate to create pyruvate and glutamate. GPT has a crucial part in the intermediary metabolism of glucose and amino acids. GPT is broadly used as an indicator of liver reliability or hepatocellular destruction in clinical tests.
EC 2.6.1.2 Preparation Products And Raw materials
Raw materials
Preparation Products
EC 2.6.1.2 Suppliers
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View Lastest Price from EC 2.6.1.2 manufacturers
- Product
- EC 2.6.1.2 9000-86-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%HPLC
- Supply Ability
- 10tons
- Release date
- 2020-01-09