ChemicalBook > CAS DataBase List > trans-3,4-Difluorocinnamic acid

trans-3,4-Difluorocinnamic acid

Product Name
trans-3,4-Difluorocinnamic acid
CAS No.
112897-97-9
Chemical Name
trans-3,4-Difluorocinnamic acid
Synonyms
AKOS 92715;RARECHEM BK HW 0122;TIMTEC-BB SBB006677;3,4-DIFLUOROCINNAMIC ACID;Phenylbutazone Impurity 35;rans-3,4-Difluorocinnamicaci;TRANS-3,4-DIFLUOROCINNAMIC ACID;trans-3,4-DifluorocinnamicAcid>trans-3,4-Difluorociamic acid,95%;trans-3,4-Difluorocinnamicacid97%
CBNumber
CB4452689
Molecular Formula
C9H6F2O2
Formula Weight
184.14
MOL File
112897-97-9.mol
More
Less

trans-3,4-Difluorocinnamic acid Property

Melting point:
194-196 °C(lit.)
Boiling point:
281.3±25.0 °C(Predicted)
Density 
1.3056 (estimate)
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
powder to crystal
pka
4.27±0.10(Predicted)
color 
White to Almost white
BRN 
7370322
CAS DataBase Reference
112897-97-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
290378
Product name
trans-3,4-Difluorocinnamic acid
Purity
95%
Packaging
5g
Price
$35.4
Updated
2023/06/20
TCI Chemical
Product number
D4161
Product name
trans-3,4-Difluorocinnamic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
D4161
Product name
trans-3,4-Difluorocinnamic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$31
Updated
2024/03/01
Alfa Aesar
Product number
B20230
Product name
3,4-Difluorocinnamic acid, 97%
Packaging
1g
Price
$25.8
Updated
2021/12/16
Alfa Aesar
Product number
B20230
Product name
3,4-Difluorocinnamic acid, 97%
Packaging
5g
Price
$84.5
Updated
2021/12/16
More
Less

trans-3,4-Difluorocinnamic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

trans-3,4-Difluorocinnamic Acid is a starting material in the preparation of Ticagrelor (T437700), which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.

trans-3,4-Difluorocinnamic acid Preparation Products And Raw materials

Raw materials

Hexane Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester Diethyl ether Ethyl acetate Sodium bicarbonate Dichloromethane tert-Butyl bromoacetate Sodium hydroxide Triphenylphosphine Magnesium sulfate 3,4-Difluorobenzaldehyde

Preparation Products

More
Less

trans-3,4-Difluorocinnamic acid Suppliers

Americas 1 Belgium 1 China 153 Europe 2 France 1 Germany 5 India 7 Italy 1 Japan 2 Switzerland 2 United Kingdom 21 United States 32 Global 228
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ChangShu Haitian Fine Chemicals Co.,Ltd
Tel
13913622609
Fax
86-512-52893680
Email
sales@haitianchem.cn
Country
China
ProdList
223
Advantage
61
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3296
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Shanghai Nuohey Chemical Co., Ltd.
Tel
021-52212593 13761626812
Fax
+86 (21) 51062076
Email
sales@nuohey.com
Country
China
ProdList
7135
Advantage
60
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1882
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6181
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9901
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai PE biochem Co.,Ltd.
Tel
+86-21-51762186
Fax
+86-21-51592879
Email
lchinsh@hotmail.com
Country
China
ProdList
94
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13358
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2071
Advantage
56
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ：245797092
Email
market@gianthx.com
Country
China
ProdList
4512
Advantage
56
Chengdu Research Accelerators Technology Co., Ltd.
Tel
028-64353063
Fax
028-64353063 QQ:784253935
Email
reacchemical@163.com
Country
China
ProdList
5259
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Wuhan Chemwish Technology Co.， Ltd
Tel
027-67849912
Fax
027-87531808
Email
sales@chemwish.com
Country
China
ProdList
9150
Advantage
60
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038 13980902949;
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1746
Advantage
55
skychemical Co.Ltd
Tel
021-20960837,QQ1332204249
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
3317
Advantage
55
Kaifute（Tianjin）Chemical Co., Ltd.
Tel
022-58659859 13820733852
Fax
022-5865 9859
Email
sales@kftchem.com
Country
China
ProdList
299
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
Nanjing XiLang Chemical Products Co., Ltd.
Tel
025-5276156 18936048580
Email
chemxilang@163.com
Country
China
ProdList
4009
Advantage
58
Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
3066
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9947
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31557
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
More
Less

View Lastest Price from trans-3,4-Difluorocinnamic acid manufacturers

Career Henan Chemical Co
Product
trans-3,4-Difluorocinnamic acid 112897-97-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10

112897-97-9, trans-3,4-Difluorocinnamic acidRelated Search:

4-(Trifluoromethyl)cinnamic acid 3,4-Dimethoxycinnamonitrile Ethyl cinnamate Methyl cinnamate Cinnamic acid Octyl 4-methoxycinnamate 4-Bromocinnamic acid Caffeic acid trans-2-(3,4-difluorophenyl) cyclopropanecarboxylic acid ((3,4-difluorophenyl) ethynyl)triMethylsilane 1,3-bis(cis-2-(3,4-difluorophenyl) cyclopropyl)urea 3-(3,4-difluorophenyl)prop-2-yn-1-ol ethyCyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)- (REACH) (E)-Methyl 3-(3,4-difluorophenyl)acrylate trans-Methyl 2-(3,4-difluorophenyl) cyclopropanecarboxylate (Z)-3-(3,4-difluorophenyl) prop-2-en-1-ol trans-2-(3,4-difluorophenyl) cyclopropanaMine (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate

  • (E)-3,4-Difluorophenylacrylic acid, (2E)-3-(3,4-Difluorophenyl)prop-2-enoic acid
  • 3,4-DIFLUOROCINNAMIC ACID
  • AKOS 92715
  • TIMTEC-BB SBB006677
  • RARECHEM BK HW 0122
  • TRANS-3,4-DIFLUOROCINNAMIC ACID
  • trans-3,4-Difluorocinnamic acid 97%
  • trans-3,4-Difluorocinnamicacid97%
  • trans-3,4-Difluorociamic acid,95%
  • (E)-3-(3,4-difluorophenyl)-2-propenoate
  • trans-3,4-DifluorocinnamicAcid&gt
  • 2-Propenoic acid, 3-(3,4-difluorophenyl)-, (2E)-
  • rans-3,4-Difluorocinnamicaci
  • trans-3-(3,4-Difluorophenyl)acrylic Acid
  • trans-3,4-Difluorocinnamic acid USP/EP/BP
  • (E)-3-(3,4-difluorophenyl)prop-2-enoic acid
  • Phenylbutazone Impurity 35
  • 112897-97-9
  • Organic Building Blocks
  • Building Blocks
  • C9
  • Carboxylic Acids
  • Carbonyl Compounds
  • Aromatic Cinnamic Acids, Esters and Derivatives
  • Cinnamic acid
  • Miscellaneous
  • C9
  • Carbonyl Compounds
  • Carboxylic Acids
  • Fluoro-contained cinnamic acid series