ChemicalBook > CAS DataBase List > 3',4'-DIHYDROXYPROPIOPHENONE

3',4'-DIHYDROXYPROPIOPHENONE

Product Name
3',4'-DIHYDROXYPROPIOPHENONE
CAS No.
7451-98-1
Chemical Name
3',4'-DIHYDROXYPROPIOPHENONE
Synonyms
Dopamine Impurity;Erlotinib Impurity 124;3,4-DIHYDROXYPROPIOPHENONE;3',4'-DIHYDROXYPROPIOPHENONE;3’,4’-dihydroxy-propiophenon;3',4'-DIHYDROXYPROPIOPHENONE;3',4'-Dihydroxypropiophenone,98%;1-(3,4-dihydroxyphenyl)-1-propanon;1-(3,4-Dihydroxyphenyl)-1-propanone;1-(3,4-dihydroxyphenyl)propan-1-one
CBNumber
CB4453934
Molecular Formula
C9H10O3
Formula Weight
166.17
MOL File
7451-98-1.mol
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3',4'-DIHYDROXYPROPIOPHENONE Property

Melting point:
145-146°C
Boiling point:
375.1±27.0 °C(Predicted)
Density 
1.237±0.06 g/cm3(Predicted)
pka
8.75±0.31(Predicted)
CAS DataBase Reference
7451-98-1(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
A13444
Product name
3',4'-Dihydroxypropiophenone, 98%
Packaging
1g
Price
$40.65
Updated
2024/03/01
Alfa Aesar
Product number
A13444
Product name
3',4'-Dihydroxypropiophenone, 98%
Packaging
5g
Price
$144.65
Updated
2024/03/01
TRC
Product number
D493333
Product name
3'',4''-Dihydroxypropiophenone
Packaging
2.5g
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD71269
Product name
3',4'-Dihydroxypropiophenone
Packaging
25g
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD71269
Product name
3',4'-Dihydroxypropiophenone
Packaging
10g
Price
$50
Updated
2021/12/16
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3',4'-DIHYDROXYPROPIOPHENONE Chemical Properties,Usage,Production

Uses

It is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Preparation

Obtained by Fries rearrangement of pyrocatechol dipropio-nate with aluminium chloride in chlorobenzene at 80° for 2 h (84%) or in nitrobenzene at 100° for 15 min;
Obtained by Fries rearrangement of pyrocatechol dipropionate with aluminium chloride in the presence of pyrocatechol, in nitrobenzene at 80° for 1 h (37%) or in nitromethane at r.t. for 72 h (76%)
Also obtained by Fries rearrangement of o-methoxyphenyl propionate (1 mol) by aluminium chloride (2 mol) without solvent at 140° for 2 h (51–55%) or in nitrobenzene at 80° for 30–60 min. A demethylation occurs during the reaction.
Also obtained by acylation of pyrocatechol with propionic acid
in the presence of boron trifluoride, at 150° for 2 h in a sealed tube ? (36%)
in the presence of polyphosphoric acid for 15 min in a boiling water bath ? (12%)
Preparation by demethylation of 4-hydroxy-3-methoxypropiophenone with refluxing pyridinium chloride for 10 min (80%)
Also obtained when propiovanillone was heated with an alkali sulfide under conditions used in the kraft cooking process.

3',4'-DIHYDROXYPROPIOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3',4'-DIHYDROXYPROPIOPHENONE Suppliers

Aladdin Scientific
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+1-+1(833)-552-7181
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3B Scientific Corporation
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Advanced Synthesis Technologies
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Alfa Aesar
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HONEST JOY HOLDINGS LIMITED
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3B Scientific Corporation
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Pfaltz & Bauer, Inc.
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7451-98-1, 3',4'-DIHYDROXYPROPIOPHENONERelated Search:


  • 1-(3,4-dihydroxyphenyl)-1-propanon
  • 3’,4’-dihydroxy-propiophenon
  • 3',4'-DIHYDROXYPROPIOPHENONE
  • 3,4-DIHYDROXYPROPIOPHENONE
  • 3',4'-Dihydroxypropiophenone,98%
  • 2-[3-(hydroxymethyl)phenoxy]acetic acid
  • 1-Propanone,1-(3,4-dihydroxyphenyl)-
  • 1-(3,4-dihydroxyphenyl)propan-1-one
  • 1-(3,4-Dihydroxyphenyl)-1-propanone
  • Erlotinib Impurity 124
  • Dopamine Impurity
  • 2,4-Dichlorobenzyl Alcohol Impurity 37
  • 3',4'-DIHYDROXYPROPIOPHENONE
  • 7451-98-1
  • Aromatic Propiophenones (substituted)