Protopine

Product Name: Protopine
CAS No.: 130-86-9
Chemical Name: Protopine
Synonyms: BIFLORIN;Protopin;PROTOPINE;Biflorine;Corydinine;Tangeratin;Hypercorine;AKOS 243-72;Corydalis C;Protopine USP/EP/BP
CBNumber: CB9347526
Molecular Formula: C20H19NO5
Formula Weight: 353.37
MOL File: 130-86-9.mol

More

Less

Protopine Property

Melting point:: 203-205?C
Boiling point:: 486.8°C (rough estimate)
Density: 1.399 (calc)
refractive index: 1.5800 (estimate)
storage temp.: Inert atmosphere,2-8°C
Water Solubility: Insoluble in water
solubility: DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic)
pka: 7.86±0.20(Predicted)
form: powder to crystal
color: White to Light gray to Light yellow
LogP: 3.760 (est)
NIST Chemistry Reference: Protopine(130-86-9)

More

Less

Safety

Safety Statements: 24/25
RIDADR: 1544
RTECS: VS2800000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29391900
Hazardous Substances Data: 130-86-9(Hazardous Substances Data)
Toxicity: guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973.

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89546
Product name: Protopine
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $425
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 5mg
Price: $45
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 25mg
Price: $130
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 100mg
Price: $355
Updated: 2024/03/01

Usbiological

Product number: 300834
Product name: Protopine
Packaging: 20mg
Price: $320
Updated: 2021/12/16

More

Less

Protopine Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator

Definition

ChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Purification Methods

It crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.]

Protopine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Protopine Suppliers

Canada 1 China 153 Czech 1 France 2 Germany 1 India 3 Japan 1 United Kingdom 4 United States 18 Global 184

Nanjing puyi biotechnology co., LTD

Tel: 025-58886740; 13814510036
Email: 927565933@qq.com
Country: China
ProdList: 1930
Advantage: 58

Nanjing Dasf Biotechnology Co., Ltd.

Tel: 025-+86-02585846866 +86-18094231287
Fax: 025-83144123
Email: eric@dasfbio.com
Country: China
ProdList: 1987
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

More

Less

View Lastest Price from Protopine manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Protopine 130-86-9
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-25

Career Henan Chemical Co

Product: Protopine 130-86-9
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

130-86-9, ProtopineRelated Search:

Methyl acetate Pirimiphos-methyl Kresoxim-methyl Tribenuron methyl METSULFURON METHYL Methyl salicylate Thiophanate-methyl Protoporphyrin IX Methyl Methyl bromide PROTOPINE HCL,PROTOPINE HYDROCHLORIDE NSC26657 DESOXYANISOIN 3-METHOXYPHENYLACETONE CORYCAVINE PIPERONYL METHYL KETONE 3'-methoxypropiophenone [2-(4-METHOXY-PHENYL)-ETHYL]-METHYL-AMINE

7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-

7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one

Biflorine

Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-

Corydinine

Hypercorine

Protopin

BIFLORIN

AKOS 243-72

5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE

PROTOPINE

4,6,7,14-Tetrahydro-5-methyl-bis[1,3]benzodioxolo[4,5-c-5',6'-g] azecin-13(5H)-one

7-Methyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one

5-Methyl-9,10-(methylenedioxy)-4,6,7,13-tetrahydrobenzo[e]-1,3-dioxolo[4,5-l][2]benzazecine-12(5H)-one

6-Methyl-3,4-(methylenebisoxy)-10,11-(methylenebisoxy)-5,6,7,8-tetrahydrodibenzo[c,g]azecine-13(14H)-one

7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one

4,6,7,14-Tetrahydro-5-Methyl-

Tangeratin

Corydalis C

Protopine (Corydinine)

Protopine, 98%, from Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu

Protopine USP/EP/BP

1H-Isoindole-1,3(2H)-dione,2-(3-butyn-2-yl)-

130-86-9

C20H19O5

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals