Protopine

Product Name: Protopine
CAS No.: 130-86-9
Chemical Name: Protopine
Synonyms: BIFLORIN;Protopin;PROTOPINE;Biflorine;Corydinine;Tangeratin;Hypercorine;AKOS 243-72;Corydalis C;Protopine USP/EP/BP
CBNumber: CB9347526
Molecular Formula: C20H19NO5
Formula Weight: 353.37
MOL File: 130-86-9.mol

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Protopine Property

Melting point:: 203-205?C
Boiling point:: 486.8°C (rough estimate)
Density: 1.399 (calc)
refractive index: 1.5800 (estimate)
storage temp.: Inert atmosphere,2-8°C
Water Solubility: Insoluble in water
solubility: DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic)
pka: 7.86±0.20(Predicted)
form: powder to crystal
color: White to Light gray to Light yellow
LogP: 3.760 (est)
NIST Chemistry Reference: Protopine(130-86-9)

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Safety

Safety Statements: 24/25
RIDADR: 1544
RTECS: VS2800000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29391900
Hazardous Substances Data: 130-86-9(Hazardous Substances Data)
Toxicity: guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89546
Product name: Protopine
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $425
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 5mg
Price: $45
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 25mg
Price: $130
Updated: 2024/03/01

TCI Chemical

Product number: P2611
Product name: Protopine
Purity: >98.0%(GC)
Packaging: 100mg
Price: $355
Updated: 2024/03/01

Usbiological

Product number: 300834
Product name: Protopine
Packaging: 20mg
Price: $320
Updated: 2021/12/16

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Protopine Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator

Definition

ChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Purification Methods

It crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.]

Protopine Preparation Products And Raw materials

Raw materials

Preparation Products

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Protopine Suppliers

Canada 1 China 154 Czech 1 France 2 Germany 1 India 3 Japan 1 United Kingdom 4 United States 18 Global 185

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28398
Advantage: 80

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View Lastest Price from Protopine manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Protopine 130-86-9
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-25

Career Henan Chemical Co

Product: Protopine 130-86-9
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

130-86-9, ProtopineRelated Search:

Methyl acetate Pirimiphos-methyl Kresoxim-methyl Tribenuron methyl METSULFURON METHYL Methyl salicylate Thiophanate-methyl Protoporphyrin IX Methyl Methyl bromide PROTOPINE HCL,PROTOPINE HYDROCHLORIDE NSC26657 DESOXYANISOIN 3-METHOXYPHENYLACETONE CORYCAVINE PIPERONYL METHYL KETONE 3'-methoxypropiophenone [2-(4-METHOXY-PHENYL)-ETHYL]-METHYL-AMINE

7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-

7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one

Biflorine

Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-

Corydinine

Hypercorine

Protopin

BIFLORIN

AKOS 243-72

5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE

PROTOPINE

4,6,7,14-Tetrahydro-5-methyl-bis[1,3]benzodioxolo[4,5-c-5',6'-g] azecin-13(5H)-one

7-Methyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one

5-Methyl-9,10-(methylenedioxy)-4,6,7,13-tetrahydrobenzo[e]-1,3-dioxolo[4,5-l][2]benzazecine-12(5H)-one

6-Methyl-3,4-(methylenebisoxy)-10,11-(methylenebisoxy)-5,6,7,8-tetrahydrodibenzo[c,g]azecine-13(14H)-one

7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one

4,6,7,14-Tetrahydro-5-Methyl-

Tangeratin

Corydalis C

Protopine (Corydinine)

Protopine, 98%, from Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu

Protopine USP/EP/BP

1H-Isoindole-1,3(2H)-dione,2-(3-butyn-2-yl)-

130-86-9

C20H19O5

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals