5-IODO-6-METHYLPYRIMIDIN-4-OL

Product Name: 5-IODO-6-METHYLPYRIMIDIN-4-OL
CAS No.: 7752-74-1
Chemical Name: 5-IODO-6-METHYLPYRIMIDIN-4-OL
Synonyms: 5-IODO-6-METHYLPYRIMIDIN-4-OL;5-Iodo-6-MethylpyriMidin-4(1H)-one;4(3H)-Pyrimidinone, 5-iodo-6-methyl-;5-IODO-6-METHYLPYRIMIDIN-4-OL ISO 9001：2015 REACH
CBNumber: CB4460158
Molecular Formula: C5H5IN2O
Formula Weight: 236.01
MOL File: 7752-74-1.mol

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5-IODO-6-METHYLPYRIMIDIN-4-OL Property

Melting point:: 238-239 °C
Boiling point:: 245.5±43.0 °C(Predicted)
Density: 2.19±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 7.92±0.50(Predicted)
Appearance: Yellow to brown Solid

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: Y5104
Product name: 5-Iodo-6-methylpyrimidin-4-ol
Packaging: 100mg
Price: $200
Updated: 2021/12/16

Chemcia Scientific

Product number: BB20-7358A
Product name: BB20-7358A
Purity: 95%
Packaging: 1g
Price: $245
Updated: 2021/12/16

Abosyn

Product number: 10-1682
Product name: 5-Iodo-6-methyl-pyrimidin-4-ol
Purity: >95%
Packaging: 1g
Price: $249
Updated: 2021/12/16

Chemenu

Product number: CM117120
Product name: 4-Hydroxy-5-iodo-6-methylpyrimidine
Purity: 95%
Packaging: 1g
Price: $421
Updated: 2021/12/16

Crysdot

Product number: CD11058592
Product name: 5-Iodo-6-methylpyrimidin-4(1H)-one
Purity: 95+%
Packaging: 1g
Price: $446
Updated: 2021/12/16

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5-IODO-6-METHYLPYRIMIDIN-4-OL Chemical Properties,Usage,Production

Synthesis

3524-87-6

7752-74-1

General procedure for the synthesis of 5-iodo-6-methylpyrimidin-4(1H)-one using 6-methylpyrimidin-4(3H)-one as starting material: 127 g (0.56 mol) of N-iodosuccinimide (NIS) was added in batches to an acetic acid solution containing 70 g (0.64 mol) of 6-methylpyrimidin-4(3H)-one at room temperature, and the addition process lasted 15 minutes. The reaction mixture was stirred at room temperature until thin layer chromatography (TLC) monitoring showed complete consumption of the feedstock (about 30 hours). Upon completion of the reaction, the mixture was diluted with water and the precipitated solid product was collected by filtration. Subsequently, the solid was washed with aqueous sodium thiosulfate to remove residual iodine. Finally, the product was dried under vacuum to give 90 g of the target compound in 60% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 6, p. 1601 - 1606
[2] Synthesis, 1984, # 3, p. 252 - 254
[3] Patent: WO2012/101184, 2012, A1. Location in patent: Page/Page column 50
[4] Patent: WO2012/101186, 2012, A1. Location in patent: Page/Page column 47
[5] Patent: EP2546249, 2013, A1. Location in patent: Paragraph 0177; 0178

5-IODO-6-METHYLPYRIMIDIN-4-OL Preparation Products And Raw materials

Raw materials

Preparation Products

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5-IODO-6-METHYLPYRIMIDIN-4-OL Suppliers

China 38 Germany 1 India 1 The Netherlands 1 United Kingdom 1 United States 1 Global 43

NovoChemy Ltd.

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Advantage: 58

Chemfun Medical Technology(Shanghai) Co., Ltd.

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Country: China
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ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
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SuZhou ShiYa Biopharmaceuticals, Inc.

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Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.

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Country: China
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Amadis Chemical Company Limited

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Shanghai Rlavie Technology Co., Ltd.

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Sichuan BaiPeng Biotechnology Co., Ltd.

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Wuxi AppTec

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SuZhou Medinoah Co.,LTD.

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View Lastest Price from 5-IODO-6-METHYLPYRIMIDIN-4-OL manufacturers

Dideu Industries Group Limited

Product: 5-IODO-6-METHYLPYRIMIDIN-4-OL 7752-74-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-08

Career Henan Chemical Co

Product: 5-IODO-6-METHYLPYRIMIDIN-4-OL 7752-74-1
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-10

7752-74-1, 5-IODO-6-METHYLPYRIMIDIN-4-OLRelated Search:

5-IODO-6-METHYLPYRIMIDIN-4-OL 4-[(5-IODO-2,6-DIMETHYL-4-PYRIMIDINYL)OXY]BENZENECARBONITRILE 5-IODO-2-ISOPROPYL-6-METHYL-PYRIMIDIN-4-OL 2,6-DIMETHYL-5-IODO-4(3H)-PYRIMIDONE 5-IODOOROTIC ACID 1-(4-CHLOROPHENYL)-2-[(5-IODO-2,6-DIMETHYL-4-PYRIMIDINYL)OXY]-1-ETHANONE 2-AMINO-4-HYDROXY-5-IODO-6-PHENYLPYRIMIDINE

5-IODO-6-METHYLPYRIMIDIN-4-OL

5-Iodo-6-MethylpyriMidin-4(1H)-one

4(3H)-Pyrimidinone, 5-iodo-6-methyl-

5-IODO-6-METHYLPYRIMIDIN-4-OL ISO 9001：2015 REACH

7752-74-1