L-SELENOCYSTINE
- Product Name
- L-SELENOCYSTINE
- CAS No.
- 29621-88-3
- Chemical Name
- L-SELENOCYSTINE
- Synonyms
- L-SELENOCYSTINE;SELENO-L-CYSTINE;L-Selenocystine,98%;L-SELENOCYSTINE 98%;Seleno-L-cystine 95%;3’-diselenodi-l-alanin;3,3'-DISELENO-L-ALANINE;l-3,3’-diselenodialanine;Seleno-
L -cystine;L-selenocysteylacetic acid - CBNumber
- CB4464888
- Molecular Formula
- C6H12N2O4Se2
- Formula Weight
- 334.09
- MOL File
- 29621-88-3.mol
L-SELENOCYSTINE Property
- Melting point:
- 224.5-229.5 °C (lit.)
- Boiling point:
- 538.3±60.0 °C(Predicted)
- storage temp.
- 2-8°C
- solubility
- Aqueous Acid (Slightly), Aqueous Base (Slightly)
- pka
- 1.69±0.10(Predicted)
- form
- Powder
- color
- Yellow
- optical activity
- [α]20/D 28°, c = 1 in NaOH
- BRN
- 1969559
- Stability:
- Hygroscopic
Safety
- Hazard Codes
- T,N
- Risk Statements
- 23/25-33-50/53
- Safety Statements
- 20/21-28-45-60-61
- RIDADR
- UN 3283 6.1/PG 3
- WGK Germany
- 3
- RTECS
- AY6032000
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P314Get medical advice/attention if you feel unwell.
N-Bromosuccinimide Price
- Product number
- 545996
- Product name
- Seleno-L-cystine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $153.72
- Updated
- 2025/07/31
- Product number
- 545996
- Product name
- Seleno-L-cystine
- Purity
- 95%
- Packaging
- 1g
- Price
- $261.13
- Updated
- 2025/07/31
- Product number
- E1368
- Product name
- L-Selenocystine
- Packaging
- 250MG
- Price
- $110
- Updated
- 2025/07/31
- Product number
- 17793
- Product name
- L-Selenocystine
- Purity
- ≥90%
- Packaging
- 50mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 17793
- Product name
- L-Selenocystine
- Purity
- ≥90%
- Packaging
- 1g
- Price
- $214
- Updated
- 2024/03/01
L-SELENOCYSTINE Chemical Properties,Usage,Production
Description
L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.
Chemical Properties
yellow fine powder
Uses
Seleno-L-cystine can be used for the synthesis of:
- Biologically active selenol compounds.
- Non-natural selenylated diamino acids.
reaction suitability
reaction type: solution phase peptide synthesis
References
[1] SPALLHOLZ J E. On the nature of selenium toxicity and carcinostatic activity[J]. Free Radical Biology and Medicine, 1994, 17 1: Pages 45-64. DOI: 10.1016/0891-5849(94)90007-8
[2] SOUGAT MISRA. Redox-active selenium compounds–from toxicity and cell death to cancer treatment.[J]. Nutrients, 2015, 7 5: 3536-3556. DOI: 10.3390/nu7053536
[3] BRIAN CUNNIFF . A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates[J]. Analytical biochemistry, 2013, 443 1: Pages 34-40. DOI: 10.1016/j.ab.2013.08.013
[4] MARITA WALLENBERG. Selenium induces a multi-targeted cell death process in addition to ROS formation[J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2014, 18 4: 671-684. DOI: 10.1111/jcmm.12214
L-SELENOCYSTINE Preparation Products And Raw materials
Raw materials
Preparation Products
L-SELENOCYSTINE Suppliers
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- 0086-512-56765862
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- 021-67121386
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- 021-67121385
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- Country
- Japan
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View Lastest Price from L-SELENOCYSTINE manufacturers
- Product
- selenocystine 29621-88-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1000
- Release date
- 2024-05-27
- Product
- L-SELENOCYSTINE 29621-88-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-03-05