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L-SELENOCYSTINE

Product Name
L-SELENOCYSTINE
CAS No.
29621-88-3
Chemical Name
L-SELENOCYSTINE
Synonyms
L-SELENOCYSTINE;SELENO-L-CYSTINE;L-Selenocystine,98%;L-SELENOCYSTINE 98%;Seleno-L-cystine 95%;3’-diselenodi-l-alanin;3,3'-DISELENO-L-ALANINE;l-3,3’-diselenodialanine;Seleno-L-cystine;L-selenocysteylacetic acid
CBNumber
CB4464888
Molecular Formula
C6H12N2O4Se2
Formula Weight
334.09
MOL File
29621-88-3.mol
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L-SELENOCYSTINE Property

Melting point:
224.5-229.5 °C (lit.)
Boiling point:
538.3±60.0 °C(Predicted)
storage temp. 
2-8°C
solubility 
Aqueous Acid (Slightly), Aqueous Base (Slightly)
pka
1.69±0.10(Predicted)
form 
Powder
color 
Yellow
optical activity
[α]20/D 28°, c = 1 in NaOH
BRN 
1969559
Stability:
Hygroscopic
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Safety

Hazard Codes 
T,N
Risk Statements 
23/25-33-50/53
Safety Statements 
20/21-28-45-60-61
RIDADR 
UN 3283 6.1/PG 3
WGK Germany 
3
RTECS 
AY6032000
HazardClass 
6.1
PackingGroup 
III
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
545996
Product name
Seleno-L-cystine
Purity
95%
Packaging
250mg
Price
$153.72
Updated
2025/07/31
Sigma-Aldrich
Product number
545996
Product name
Seleno-L-cystine
Purity
95%
Packaging
1g
Price
$261.13
Updated
2025/07/31
TCI Chemical
Product number
E1368
Product name
L-Selenocystine
Packaging
250MG
Price
$110
Updated
2025/07/31
Cayman Chemical
Product number
17793
Product name
L-Selenocystine
Purity
≥90%
Packaging
50mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17793
Product name
L-Selenocystine
Purity
≥90%
Packaging
1g
Price
$214
Updated
2024/03/01
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L-SELENOCYSTINE Chemical Properties,Usage,Production

Description

L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.

Chemical Properties

yellow fine powder

Uses

Seleno-L-cystine can be used for the synthesis of:

  • Biologically active selenol compounds.
  • Non-natural selenylated diamino acids.

reaction suitability

reaction type: solution phase peptide synthesis

References

[1] SPALLHOLZ J E. On the nature of selenium toxicity and carcinostatic activity[J]. Free Radical Biology and Medicine, 1994, 17 1: Pages 45-64. DOI: 10.1016/0891-5849(94)90007-8
[2] SOUGAT MISRA. Redox-active selenium compounds–from toxicity and cell death to cancer treatment.[J]. Nutrients, 2015, 7 5: 3536-3556. DOI: 10.3390/nu7053536
[3] BRIAN CUNNIFF . A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates[J]. Analytical biochemistry, 2013, 443 1: Pages 34-40. DOI: 10.1016/j.ab.2013.08.013
[4] MARITA WALLENBERG. Selenium induces a multi-targeted cell death process in addition to ROS formation[J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2014, 18 4: 671-684. DOI: 10.1111/jcmm.12214

L-SELENOCYSTINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L-SELENOCYSTINE manufacturers

Apeloa production Co.,Limited
Product
selenocystine 29621-88-3
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
1000
Release date
2024-05-27
Career Henan Chemical Co
Product
L-SELENOCYSTINE 29621-88-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-03-05

29621-88-3, L-SELENOCYSTINERelated Search:

Selenium selenium-bridged-6,6'-amino-selenocystine-6,6'-deoxy-di-cyclodextrin D-Selenocystine D-selenocystine alpha, beta-lyase d,l-selenocystin Selenocystine DI-FMOC-SELENO-L-CYSTINE DI-BOC-SELENO-L-CYSTINE Dimethyldiselenide D,L-SELENOCYSTEINE DIPROPYLDISELENIDE selenocystamine DIETHYLDISELENIDE L-SELENOCYSTINE

  • SELENO-L-CYSTINE
  • (R,R)-3,3'-DISELENO-BIS(2-AMINOPROPIONIC ACID)
  • L-SELENOCYSTINE
  • 3’-diselenodi-l-alanin
  • l-3,3’-diselenodialanine
  • 3,3'-DISELENO-L-ALANINE
  • L-SELENOCYSTINE 98%
  • (R,R)-3,3μ-Diseleno-bis(2-aminopropionic acid), L-Selenocystine
  • L-Selenocystine,98%
  • Seleno-L-cystine,(R,R)-3,3′-Diseleno-bis(2-aminopropionic acid), L-Selenocystine
  • L-Selenocystine Monohydrate
  • Alanine, 3,3'-diselenodi-, L-
  • Seleno-L-cystine 95%
  • 2-Amino-3-(((R)-2-amino-2-carboxyethyl)diselanyl)propanoic acid
  • L-Alanine,3,3'-diselenobis-
  • L-selenocysteylacetic acid
  • L-Selenocystine Monohydrate&gt
  • (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoic acid
  • (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoicaci
  • (2R,2'R)-3,3'-Diselanediylbis(2-aminopropanoic acid)
  • anti-oxidant,LSelenocystine,cancer,amino acid,inhibit,Inhibitor,L Selenocystine,pro-oxidant,HeLa
  • L-Selenocystine, 10 mM in DMSO
  • Seleno-<sc>L</sc>-cystine
  • 29621-88-3
  • C6H12N2O4Se2H2O
  • CO2HCHNH2CH2Se2CH2CHNH2CO2H
  • C6H12N2O4Se2
  • Cysteine Derivatives
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Peptide Synthesis
  • amino acids