Fmoc-N-amido-PEG24-acid
- Product Name
- Fmoc-N-amido-PEG24-acid
- CAS No.
- 2170484-59-8
- Chemical Name
- Fmoc-N-amido-PEG24-acid
- Synonyms
- Fmoc-NH-PEG;CAS_2170484-59-8;Fmoc-N-PEG24-acid;FmocNH-PEG24-COOH;Fmoc-PEG24-propionic acid;Fmoc-N-amido-PEG24-acid - n=24;(Fmoc-amino)-PEG24-C2-Carboxylic Acid;1-(9H-Fluoren-9-ylmethyl) 5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74-tetracosaoxa-2-azaheptaheptacontanedioate;1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxa-4-azanonaheptacontan-79-oic acid;5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74-Tetracosaoxa-2-azaheptaheptacontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
- CBNumber
- CB44660893
- Molecular Formula
- C66H113NO28
- Formula Weight
- 1368.59
- MOL File
- 2170484-59-8.mol
Fmoc-N-amido-PEG24-acid Property
- Boiling point:
- 1108.7±65.0 °C(Predicted)
- Density
- 1.152±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, sealed storage, away from moisture
- form
- powder
- pka
- 4.28±0.10(Predicted)
- color
- White
- InChIKey
- NFOMZHGRFWXDGH-UHFFFAOYSA-N
- SMILES
- C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Safety
- HS Code
- 3822000000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- BIPG1407
- Product name
- Fmoc-N-amido-PEG24-acid
- Packaging
- 100mg
- Price
- $399
- Updated
- 2021/12/16
Fmoc-N-amido-PEG24-acid Chemical Properties,Usage,Production
Description
Fmoc-N-amido-PEG24-acid contains an Fmoc-protected amine and a terminal carboxylic acid. The PEG spacer increases the aqueous solubility of the resulting compound. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond.
Uses
Fmoc-N-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-N-amido-PEG24-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-N-amido-PEG24-acid Suppliers
- Tel
- +81-8027837258; +8108027837258
- Fax
- 0081-80278372055
- sales@adachibio.com
- Country
- Japan
- ProdList
- 992
- Advantage
- 58
View Lastest Price from Fmoc-N-amido-PEG24-acid manufacturers
- Product
- Fmoc-NH-PEG24-CH2CH2COOH 2170484-59-8
- Price
- US $1652.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-17
- Product
- 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxa-4-azanonaheptacontan-79-oic acid 2170484-59-8
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 2170484-59-8
- Release date
- 2025-09-12
- Product
- Fmoc-N-amido-PEG24-acid 2170484-59-8
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >99.00%
- Supply Ability
- 1g
- Release date
- 2024-03-28