Fmoc-NH-PEG12-CH2CH2COOH
- Product Name
- Fmoc-NH-PEG12-CH2CH2COOH
- CAS No.
- 1952360-91-6
- Chemical Name
- Fmoc-NH-PEG12-CH2CH2COOH
- Synonyms
- 5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester;Fmoc-nh-peg(16)-cooh;Fmoc-nh-peg12-C2-cooh;FMoc-NH-PEG12-CH2CH2COOH;Carboxy-PEG12-(Fmoc-amine);Fmoc-N-amido-PEG12-propionic acid;(Fmoc-amino)-PEG12-C2-Carboxylic Acid;Inhibitor,Fmoc-NH-PEG-12-CH2CH2COOH,inhibit,Fmoc NH PEG12 CH2CH2COOH,PROTAC Linkers,FmocNHPEG12CH2CH2COOH;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxa-4-azatritetracontan-43-oic Acid;FmocNH-PEG12-CH2CH2COOH/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
- CBNumber
- CB53371186
- Molecular Formula
- C42H65NO16
- Formula Weight
- 839.96
- MOL File
- 1952360-91-6.mol
Fmoc-NH-PEG12-CH2CH2COOH Property
- Boiling point:
- 870.4±65.0 °C(Predicted)
- Density
- 1.175±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 4.28±0.10(Predicted)
- form
- clear liquid
- color
- Colorless to Light yellow
- InChIKey
- JYNHRDJTWNEGJE-UHFFFAOYSA-N
- SMILES
- C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Safety
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- F1238
- Product name
- (Fmoc-amino)-PEG12-C2-Carboxylic Acid
- Packaging
- 100MG
- Price
- $356
- Updated
- 2025/07/31
- Product number
- BIPG1405
- Product name
- Fmoc-N-amido-PEG12-Acid
- Packaging
- 100mg
- Price
- $399
- Updated
- 2021/12/16
- Product number
- BP-21632
- Product name
- Fmoc-N-amido-PEG12-acid
- Purity
- 98%
- Packaging
- 500mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- 39659
- Product name
- (Fmoc-amino)-PEG12-C2-carboxylicacid,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 100MG
- Price
- $469.28
- Updated
- 2021/12/16
- Product number
- BIPG1405
- Product name
- Fmoc-N-amido-PEG12-Acid
- Packaging
- 50mg
- Price
- $254
- Updated
- 2021/12/16
Fmoc-NH-PEG12-CH2CH2COOH Chemical Properties,Usage,Production
Description
Fmoc-N-amido-PEG12-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
General Description
FmocNH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker. Fmoc-NH-PEG12-CH2CH2COOH can be used in the synthesis of PROTAC.
IC 50
PEGs
storage
Keep in dark place,Inert atmosphere,Store in freezer, under -20 ℃.
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-NH-PEG12-CH2CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Fmoc-NH-PEG12-CH2CH2COOH manufacturers
- Product
- Fmoc-NH-PEG12-CH2CH2COOH 1952360-91-6
- Price
- US $283.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-17
- Product
- Fmoc-N-amido-PEG12-acid 1952360-91-6
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >99.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25