ChemicalBook > CAS DataBase List > Fmoc-NH-PEG12-CH2CH2COOH

Fmoc-NH-PEG12-CH2CH2COOH

Product Name
Fmoc-NH-PEG12-CH2CH2COOH
CAS No.
1952360-91-6
Chemical Name
Fmoc-NH-PEG12-CH2CH2COOH
Synonyms
5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester;FmocHN-PEG12-PA;Fmoc-nh-peg(16)-cooh;Fmoc-nh-peg12-C2-cooh;Fmoc-N-amido-PEG12-PA;FMoc-NH-PEG12-CH2CH2COOH;Carboxy-PEG12-(Fmoc-amine);Fmoc-N-amido-PEG12-propionic acid;(Fmoc-amino)-PEG12-C2-Carboxylic Acid;Inhibitor,Fmoc-NH-PEG-12-CH2CH2COOH,inhibit,Fmoc NH PEG12 CH2CH2COOH,PROTAC Linkers,FmocNHPEG12CH2CH2COOH
CBNumber
CB53371186
Molecular Formula
C42H65NO16
Formula Weight
839.96
MOL File
1952360-91-6.mol
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Fmoc-NH-PEG12-CH2CH2COOH Property

Boiling point:
870.4±65.0 °C(Predicted)
Density 
1.175±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
4.28±0.10(Predicted)
form 
clear liquid
color 
Colorless to Light yellow
InChIKey
JYNHRDJTWNEGJE-UHFFFAOYSA-N
SMILES
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
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Safety

HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F1238
Product name
(Fmoc-amino)-PEG12-C2-Carboxylic Acid
Packaging
100MG
Price
$285
Updated
2026/03/19
Iris Biotech GmbH
Product number
PEG1080
Product name
Fmoc-NH-PEG(12)-COOH
Packaging
100mg
Price
$351
Updated
2021/12/16
Apolloscientific
Product number
BIPG1405
Product name
Fmoc-N-amido-PEG12-Acid
Packaging
100mg
Price
$399
Updated
2021/12/16
BroadPharm
Product number
BP-21632
Product name
Fmoc-N-amido-PEG12-acid
Purity
98%
Packaging
500mg
Price
$400
Updated
2021/12/16
Chem-Impex
Product number
39659
Product name
(Fmoc-amino)-PEG12-C2-carboxylicacid,98%(HPLC)
Purity
98%(HPLC)
Packaging
100MG
Price
$469.28
Updated
2021/12/16
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Fmoc-NH-PEG12-CH2CH2COOH Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG12-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

General Description

FmocNH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker. Fmoc-NH-PEG12-CH2CH2COOH can be used in the synthesis of PROTAC.

IC 50

PEGs

storage

Keep in dark place,Inert atmosphere,Store in freezer, under -20 ℃.

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-NH-PEG12-CH2CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-NH-PEG12-CH2CH2COOH Suppliers

Xinyanpomei
Tel
15850660754
Email
15850660754@163.com
Country
China
ProdList
1204
Advantage
58
Chengdu Pukang Biotechnology Co., Ltd
Tel
15680681408 18217049878
Fax
086-28-82550468
Email
cassie.gao@pu-kang.com
Country
China
ProdList
468
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
973
Advantage
59
Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
Email
981810490@qq.com
Country
China
ProdList
1566
Advantage
58
Affinity(Wuhan)Ltd.
Tel
15841022315
Email
sales@affinitytech.cn
Country
China
ProdList
2967
Advantage
58
Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.
Tel
19981275275
Email
sales@zsdpharm.com
Country
China
ProdList
347
Advantage
58
Affinity Linkers Ltd.
Tel
18171240527 18171240527
Email
linkers@affinitytech.cn
Country
China
ProdList
6549
Advantage
58
Changsha Morning Shine Co., Ltd.
Tel
189-75832125 13397510867
Email
BD@csmspharm.com
Country
China
ProdList
522
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Biomatrik (Jiaxing) Inc.
Tel
0573-82623377 18967387295
Fax
+86 (573) 8262-3317
Email
sales@biomatrik.cn
Country
China
ProdList
50
Advantage
61
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View Lastest Price from Fmoc-NH-PEG12-CH2CH2COOH manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Fmoc-N-amido-PEG12-PA 1952360-91-6
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-06
LAURENT
Product
Fmoc-NH-PEG12-CH2CH2COOH 1952360-91-6
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2026-01-28
Xian confluore Biological Technology Co., Ltd.
Product
Fmoc-N-amido-PEG12-acid 1952360-91-6
Price
US $0.00/g
Min. Order
5g
Purity
>99.00%
Supply Ability
5g
Release date
2024-03-25

1952360-91-6, Fmoc-NH-PEG12-CH2CH2COOHRelated Search:


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  • Carboxy-PEG12-(Fmoc-amine)
  • Inhibitor,Fmoc-NH-PEG-12-CH2CH2COOH,inhibit,Fmoc NH PEG12 CH2CH2COOH,PROTAC Linkers,FmocNHPEG12CH2CH2COOH
  • FmocNH-PEG12-CH2CH2COOH/5,8,11,14,17,20,23,26,29,32,35,38-Dodecaoxa-2-azahentetracontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
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