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Fmoc-N-amido-PEG24-acid

Product Name
Fmoc-N-amido-PEG24-acid
CAS No.
2170484-59-8
Chemical Name
Fmoc-N-amido-PEG24-acid
Synonyms
Fmoc-NH-PEG;CAS_2170484-59-8;Fmoc-N-PEG24-acid;FmocNH-PEG24-COOH;Fmoc-PEG24-propionic acid;Fmoc-N-amido-PEG24-acid - n=24;(Fmoc-amino)-PEG24-C2-Carboxylic Acid;1-(9H-Fluoren-9-ylmethyl) 5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74-tetracosaoxa-2-azaheptaheptacontanedioate;1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxa-4-azanonaheptacontan-79-oic acid;5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74-Tetracosaoxa-2-azaheptaheptacontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
CBNumber
CB44660893
Molecular Formula
C66H113NO28
Formula Weight
1368.59
MOL File
2170484-59-8.mol
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Fmoc-N-amido-PEG24-acid Property

Boiling point:
1108.7±65.0 °C(Predicted)
Density 
1.152±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, sealed storage, away from moisture
form 
powder
pka
4.28±0.10(Predicted)
color 
White
InChIKey
NFOMZHGRFWXDGH-UHFFFAOYSA-N
SMILES
C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
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Safety

HS Code 
3822000000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Apolloscientific
Product number
BIPG1407
Product name
Fmoc-N-amido-PEG24-acid
Packaging
100mg
Price
$399
Updated
2021/12/16
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Fmoc-N-amido-PEG24-acid Chemical Properties,Usage,Production

Description

Fmoc-N-amido-PEG24-acid contains an Fmoc-protected amine and a terminal carboxylic acid. The PEG spacer increases the aqueous solubility of the resulting compound. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond.

Uses

Fmoc-N-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Fmoc-N-amido-PEG24-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-N-amido-PEG24-acid Suppliers

Shanghai Yanfen Biochemical Technology Co.,LTD
Tel
17721070236 15002190549;
Email
yanfen2023@126.com
Country
China
ProdList
1837
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58
Zhejiang Rui 'ao Biological Technology Co.,LTD.
Tel
+86-573-82087565 15757883359
Email
yan@ruiaochem.cn
Country
China
ProdList
640
Advantage
58
Changsha Morning Shine Co., Ltd.
Tel
189-75832125 13397510867
Email
BD@csmspharm.com
Country
China
ProdList
399
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
970
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Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
Email
981810490@qq.com
Country
China
ProdList
1566
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58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
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58
Chemyouth Life Science(Suzhou)Co.,Ltd
Tel
13752065514
Email
jianwei@chemyouth.com
Country
China
ProdList
133
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58
Affinity(Wuhan)Ltd.
Tel
15841022315
Email
sales@affinitytech.cn
Country
China
ProdList
3000
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58
Biomatrik (Jiaxing) Inc.
Tel
573-573-82623377 18967387295
Fax
+86 (573) 8262-3317
Email
sales@biomatrik.cn
Country
China
ProdList
70
Advantage
61
Chengdu Pukang Biotechnology Co., Ltd
Tel
+86-028-82550498 +86-19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
497
Advantage
58
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View Lastest Price from Fmoc-N-amido-PEG24-acid manufacturers

LAURENT
Product
Fmoc-NH-PEG24-CH2CH2COOH 2170484-59-8
Price
US $1652.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-17
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxa-4-azanonaheptacontan-79-oic acid 2170484-59-8
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
2170484-59-8
Release date
2025-09-12
Xian confluore Biological Technology Co., Ltd.
Product
Fmoc-N-amido-PEG24-acid 2170484-59-8
Price
US $0.00/g
Min. Order
1g
Purity
>99.00%
Supply Ability
1g
Release date
2024-03-28

2170484-59-8, Fmoc-N-amido-PEG24-acidRelated Search:


  • CAS_2170484-59-8
  • (Fmoc-amino)-PEG24-C2-Carboxylic Acid
  • Fmoc-N-PEG24-acid
  • 5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74-Tetracosaoxa-2-azaheptaheptacontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxa-4-azanonaheptacontan-79-oic acid
  • FmocNH-PEG24-CH2CH2COOH/5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74-Tetracosaoxa-2-azaheptaheptacontanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • Fmoc-PEG24-propionic acid
  • Fmoc-NH-PEG
  • Fmoc-N-amido-PEG24-acid - n=24
  • FmocNH-PEG24-COOH
  • 1-(9H-Fluoren-9-ylmethyl) 5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74-tetracosaoxa-2-azaheptaheptacontanedioate
  • 2170484-59-8
  • C66H113NO28