ChemicalBook > CAS DataBase List > Remibrutinib

Remibrutinib

Product Name
Remibrutinib
CAS No.
1787294-07-8
Chemical Name
Remibrutinib
Synonyms
LOU064;LOU-064;REMIBRUTINIB;Remibrutinib (LOU064);Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase;N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide;N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide;N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide;Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-
CBNumber
CB44675356
Molecular Formula
C27H27F2N5O3
Formula Weight
507.53
MOL File
1787294-07-8.mol
More
Less

Remibrutinib Property

Boiling point:
634.8±55.0 °C(Predicted)
Density 
1.332±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 125 mg/mL (246.29 mM)
form 
Solid
pka
11.67±0.70(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-0103905
Product name
Remibrutinib
Purity
99.26%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0103905
Product name
Remibrutinib
Purity
99.26%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0103905
Product name
Remibrutinib
Purity
99.26%
Packaging
50mg
Price
$1650
Updated
2021/12/16
ChemScene
Product number
CS-0103905
Product name
Remibrutinib
Purity
99.26%
Packaging
100mg
Price
$2250
Updated
2021/12/16
More
Less

Remibrutinib Chemical Properties,Usage,Production

Description

Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.

Chemical Properties

White to off-white Solid

Remibrutinib Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Remibrutinib Suppliers

China 43 United States 3 Global 46
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58

1787294-07-8, RemibrutinibRelated Search:


  • LOU064
  • LOU-064
  • REMIBRUTINIB
  • N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide
  • Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-
  • Remibrutinib (LOU064)
  • N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide
  • Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase
  • N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide
  • 1787294-07-8
  • C27H27F2N5O3