ChemicalBook > CAS DataBase List > Remibrutinib
Remibrutinib
- Product Name
- Remibrutinib
- CAS No.
- 1787294-07-8
- Chemical Name
- Remibrutinib
- Synonyms
- LOU064;LOU-064;REMIBRUTINIB;Lou064/Remibrutinib;Remibrutinib (LOU064);Remibrutinib, 10 mM in DMSO;Remibrutinib (LOU064) ，S9660;Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase;N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide;N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide
- CBNumber
- CB44675356
- Molecular Formula
- C27H27F2N5O3
- Formula Weight
- 507.53
- MOL File
- 1787294-07-8.mol
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Remibrutinib Property
- Boiling point:
- 634.8±55.0 °C(Predicted)
- Density
- 1.332±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 125 mg/mL (246.29 mM)
- form
- Solid
- pka
- 11.67±0.70(Predicted)
- color
- White to off-white
- InChIKey
- CUABMPOJOBCXJI-UHFFFAOYSA-N
- SMILES
- C(NC1=CC(F)=CC(C2C(OCCN(C)C(=O)C=C)=C(N)N=CN=2)=C1C)(=O)C1=CC=C(C2CC2)C=C1F
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0103905
- Product name
- Remibrutinib
- Purity
- 99.26%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0103905
- Product name
- Remibrutinib
- Purity
- 99.26%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0103905
- Product name
- Remibrutinib
- Purity
- 99.26%
- Packaging
- 50mg
- Price
- $1650
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0103905
- Product name
- Remibrutinib
- Purity
- 99.26%
- Packaging
- 100mg
- Price
- $2250
- Updated
- 2021/12/16
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Remibrutinib Chemical Properties,Usage,Production
Description
Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.
Chemical Properties
White to off-white Solid
Uses
Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood[1]. Remibrutinib has the potential for Chronic urticaria (CU) treatment[2].
References
[1] Daniela Angst, et al. Novel amino pyrimidine derivatives. Patent WO2015079417A1.
[2] Kolkhir P, et al. New treatments for chronic urticaria. Ann Allergy Asthma Immunol. 2019 Aug 23. DOI:10.1016/j.anai.2019.08.014
Remibrutinib Preparation Products And Raw materials
Raw materials
Preparation Products
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Remibrutinib Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
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View Lastest Price from Remibrutinib manufacturers
Shanghai Joiny Pharmaceutical Co.,LTD
- Product
- Remibrutinib 1787294-07-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-11-12
Zison Pharmaceutical (Shandong) Co., Ltd.
- Product
- Remibrutinib 1787294-07-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- ＞98% by HPLC
- Supply Ability
- 200kg/month
- Release date
- 2025-10-10
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
- Product
- Remibrutinib 1787294-07-8
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 100kg/Month
- Release date
- 2025-09-10