MS4078

Product Name: MS4078
CAS No.: 2229036-62-6
Chemical Name: MS4078
Synonyms: MS4078;MS4078 ，S0072;MS-4078;MS 4078;MS4078, 10 mM in DMSO;MS-4078,Anaplastic lymphoma kinase,CD246,Inhibitor,MS4078,ALK tyrosine kinase receptor,inhibit,Anaplastic lymphoma kinase (ALK),MS 4078,PROTACs,Cluster of differentiation 246;2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)acetamide;4-[4-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-1-piperidineacetamide;1-Piperidineacetamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-
CBNumber: CB44718707
Molecular Formula: C45H52ClN9O8S
Formula Weight: 914.47
MOL File: 2229036-62-6.mol

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MS4078 Property

Density: 1.377±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (54.68 mM; Need ultrasonic)
pka: 10.74±0.40(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0043499
Product name: MS4078
Purity: 99.63%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0043499
Product name: MS4078
Purity: 99.63%
Packaging: 50mg
Price: $750
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611306
Product name: MS4078
Purity: >98%
Packaging: 10mg
Price: $838.1
Updated: 2021/12/16

ChemScene

Product number: CS-0043499
Product name: MS4078
Purity: 99.63%
Packaging: 100mg
Price: $1250
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611306
Product name: MS4078
Purity: >98%
Packaging: 25mg
Price: $1504.5
Updated: 2021/12/16

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MS4078 Chemical Properties,Usage,Production

Description

MS4078 is a heterobifunctional linker that binds to protein targets and delivers cytotoxic drugs to cancer cells. It has a selective binding affinity for cancer cells and has shown minimal toxicity in pre-clinical studies.

Uses

MS4078 is an inhibitor and PROTAC (degrader) of ALK.

IC 50

ALK; Cereblon

MS4078 Preparation Products And Raw materials

Raw materials

Preparation Products

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MS4078 Suppliers

CHINA 46 United States 3 Global 49

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4800
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9531
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shanghai finete Pharmaceutical Co., Ltd.

Tel: 021-021-00000000 18221039705
Fax: QQ:17263424
Email: finetechpharm@126.com
Country: China
ProdList: 214
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1623
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Wuhan Fortuna Chemical Co., Ltd

Tel: +86-027-59207850 +86-13986145403;
Fax: 86-27-59524646
Email: info@fortunachem.com
Country: China
ProdList: 6011
Advantage: 58

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View Lastest Price from MS4078 manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: MS4078 2229036-62-6
Price: US $0.00/mg
Min. Order: 1mg
Purity: 98%min
Supply Ability: 500mg
Release date: 2021-08-26

2229036-62-6, MS4078Related Search:

1H-Isoindole-1,3(2H)-dione, 4-[[2-[4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]-2-oxoethyl]amino]-2-(2,6-dioxo-3-piperidinyl)- MS1943 MS4077

MS4078

MS-4078;MS 4078

1-Piperidineacetamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-

2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)acetamide

MS-4078,Anaplastic lymphoma kinase,CD246,Inhibitor,MS4078,ALK tyrosine kinase receptor,inhibit,Anaplastic lymphoma kinase (ALK),MS 4078,PROTACs,Cluster of differentiation 246

MS4078, 10 mM in DMSO

MS4078 ，S0072

4-[4-[[5-Chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-1-piperidineacetamide

2229036-62-6

C45H52ClN9O8S