PAT-1251

Product Name: PAT-1251
CAS No.: 2007885-39-2
Chemical Name: PAT-1251
Synonyms: PAT 1251,PAT1251;Lenumlostat (PAT-1251);PAT-1251, 10 mM in DMSO;rel-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone;Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel-
CBNumber: CB44797092
Molecular Formula: C18H17F4N3O3
Formula Weight: 399.34
MOL File: 2007885-39-2.mol

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PAT-1251 Property

Boiling point:: 540.7±50.0 °C(Predicted)
Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 130 mg/mL (325.54 mM)
form: Solid
pka: 13.23±0.40(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 5mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 10mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 25mg
Price: $1950
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 50mg
Price: $2950
Updated: 2021/12/16

ChemScene

Product number: CS-0028450
Product name: PAT-1251
Purity: 98.17%
Packaging: 100mg
Price: $4500
Updated: 2021/12/16

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PAT-1251 Chemical Properties,Usage,Production

Uses

PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases[1].

References

[1] Rowbottom MW, et al. Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2). J Med Chem. 2017 May 25;60(10):4403-4423. DOI:10.1021/acs.jmedchem.7b00345

PAT-1251 Preparation Products And Raw materials

Raw materials

Preparation Products

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PAT-1251 Suppliers

China 17 United States 3 Global 20

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2389
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4181
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988941452
Fax: QQ：3283937693
Email: YN_research@163.com
Country: China
ProdList: 3011
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

2007885-39-2, PAT-1251Related Search:

Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel-

PAT 1251,PAT1251

rel-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone

PAT-1251, 10 mM in DMSO

Lenumlostat (PAT-1251)

2007885-39-2