ChemicalBook > CAS DataBase List > 22-(tert-Butoxy)-22-oxodocosanoic acid

22-(tert-Butoxy)-22-oxodocosanoic acid

Product Name
22-(tert-Butoxy)-22-oxodocosanoic acid
CAS No.
1642333-05-8
Chemical Name
22-(tert-Butoxy)-22-oxodocosanoic acid
Synonyms
22-(tert-butoxy)-22-oxoicosanoic acid;22-(tert-Butoxy)-22-oxodocosanoic acid;Docosanedioic acid, 1-(1,1-dimethylethyl) ester;Docosanedioic acid, mono(1,1-dimethylethyl) ester
CBNumber
CB44798433
Molecular Formula
C26H50O4
Formula Weight
426.67
MOL File
1642333-05-8.mol
More
Less

22-(tert-Butoxy)-22-oxodocosanoic acid Property

storage temp. 
Storage temp. 2-8°C
form 
powder
color 
White
InChI
InChI=1S/C26H50O4/c1-26(2,3)30-25(29)23-21-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-22-24(27)28/h4-23H2,1-3H3,(H,27,28)
InChIKey
OXPWLSZVTHVKQN-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCCCCCC(O)=O
More
Less

Safety

HS Code 
2917198090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More
Less

N-Bromosuccinimide Price

SynQuest Laboratories
Product number
2123-1-87
Product name
22-(tert-Butoxy)-22-oxodocosanoic acid
Packaging
250mg
Price
$600
Updated
2021/12/16
Activate Scientific
Product number
AS145122
Product name
22-(tert-Butoxy)-22-oxodocosanoicacid
Purity
97%
Packaging
1g
Price
$1348
Updated
2021/12/16
Ambeed
Product number
A971470
Product name
22-(tert-Butoxy)-22-oxodocosanoicacid
Purity
97%
Packaging
100g
Price
$2534
Updated
2021/12/16
Ambeed
Product number
A1490292
Product name
22-(tert-Butoxy)-22-oxodocosanoicacid
Purity
98+%
Packaging
100g
Price
$2534
Updated
2021/12/16
Ambeed
Product number
A1490292
Product name
22-(tert-Butoxy)-22-oxodocosanoicacid
Purity
98+%
Packaging
25g
Price
$774
Updated
2021/12/16
More
Less

22-(tert-Butoxy)-22-oxodocosanoic acid Chemical Properties,Usage,Production

Uses

22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t

IC 50

Non-cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. DOI:10.1038/nrd.2016.268
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

22-(tert-Butoxy)-22-oxodocosanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

22-(tert-Butoxy)-22-oxodocosanoic acid Suppliers

China 50 United Kingdom 1 United States 4 Global 55
Zhengzhou anmousse chemical products co. LTD
Tel
0371-55289822 18737195735
Fax
QQ:483339295
Email
483339295@qq.com
Country
China
ProdList
7587
Advantage
58
Nanjing Machido Pharmaceutical Technology Co., Ltd.
Tel
19556085883
Fax
QQ:1494490951
Email
sales@machidopharma.com
Country
China
ProdList
394
Advantage
58
Shanghai Xianer Chemical Technology Co., Ltd.
Tel
021-021-60556752 15800818924
Email
3423935586@qq.com
Country
China
ProdList
112
Advantage
58
Henan Mengtai Pharmaceutical Technology Co., Ltd
Tel
176345344 7 17634854698
Email
1959525201@qq.com
Country
China
ProdList
10000
Advantage
58
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10110
Advantage
58
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9755
Advantage
58
Zhengzhou JACS Chemical Co., Ltd.
Tel
0371-0371-86259281 15981966935
Fax
0371-86259281
Email
jacschem@163.com
Country
China
ProdList
2005
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15083
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
14948
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
CR Corporation Limited
Tel
+8613062833949
Email
fred.wen@crcorporation.cn
Country
China
ProdList
8645
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
Country
China
ProdList
14081
Advantage
58
SANBEM Biotech (Suzhou) Co., Ltd.
Tel
0512-85667806 18551283436
Fax
0512-85667816
Email
sales@sanbem.com
Country
China
ProdList
3018
Advantage
58
Henan Lavoisier Chemical Products Co. Ltd
Tel
0371-63682289 18625781376
Fax
18625781376
Email
jacschem@163.com
Country
China
ProdList
4967
Advantage
58
Wuhan Linglingjiu Biotechnology Co., Ltd
Tel
15623309010
Email
1287744812@qq.com
Country
China
ProdList
963
Advantage
58
Zhengzhou convergence chemical co., LTD
Tel
0371-0371-55153829 18003835034
Email
2853979819@qq.com
Country
China
ProdList
9998
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
029-029-81120477 17792793610
Email
1033@dideu.com
Country
China
ProdList
9963
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6979
Advantage
58
Anhui DIHE Yongxin Pharmaceutical Co., Ltd.
Tel
0556-05565590630
Email
wangqi@desano.com
Country
China
ProdList
310
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29784
Advantage
58
Henan Dowon Chemical Technology Co., Ltd.
Tel
16696119288
Email
779113375@qq.com
Country
China
ProdList
7236
Advantage
58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
Tel
13770887460
Email
wenxi@jszkhy.com
Country
China
ProdList
1354
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Chengdu Dihe Yongxin Pharmaceutical Technology Co., Ltd
Tel
15928140810 13928288528
Email
lixueyin@desano.com
Country
China
ProdList
196
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
Nanjing Jianao Pharmaceutical Technology Co., Ltd.
Tel
18915922978 15852919878;
Email
497743262@qq.com
Country
China
ProdList
996
Advantage
58
Chengdu Hanwei Biotechnology Co., Ltd
Tel
17360178904 18217049878
Email
zengzongwen@pegtide.com
Country
China
ProdList
1222
Advantage
58
Honghanyanxin Pharm
Tel
0551-62626652 19334025048
Email
sales-honghanyanxin@aliyun.com
Country
China
ProdList
1164
Advantage
58
Shaoyuan Technology (Shanghai) Co., Ltd.
Tel
021-50795510 4000665055
Email
sy-c5@accelachem.com
Country
China
ProdList
10000
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
400-6206333 13167063860
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
48457
Advantage
58
Changsha Morning Shine Co., Ltd.
Tel
189-75832125 13397510867
Email
BD@csmspharm.com
Country
China
ProdList
399
Advantage
58
Hubei wei shi reagent group ltd., company
Tel
027-59101766 13125137661
Email
2853877621@qq.com
Country
China
ProdList
7979
Advantage
58
Tianjin Rongshen Chemical Co., Ltd
Tel
18317763565; 18317763565
Email
18317763565@163.com
Country
China
ProdList
9516
Advantage
58
Shanghai Hansi Chemical Industry Co., Ltd.
Tel
17717618050
Email
zllg@gh-reagent.com
Country
China
ProdList
10420
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 13308200041
Email
2851167782@qq.com
Country
China
ProdList
11146
Advantage
58
Smilepep (Hangzhou) Pharmatech Co.,Ltd.
Tel
13666671253
Email
xu@smilepep.com
Country
China
ProdList
100
Advantage
58
Sichuan jiayinglai technology CO.,LTD
Tel
028-64159575
Email
1678230860@qq.com
Country
China
ProdList
6511
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Chongqing jooe co., ltd
Tel
+undefined86-15223382610
Email
info@jooe.com
Country
China
ProdList
6208
Advantage
58
Changsha Morning Shine Co., Ltd.
Tel
+8613751227286
Email
chenkaijie@csmspharm.com
Country
China
ProdList
300
Advantage
58
Anhuyan (Hainan) Biotechnology Co., LTD
Tel
+86-18163349544; +8618163349544
Email
mollylucking@foxmail.com
Country
China
ProdList
3000
Advantage
58
Hebei Chuanghai Biotechnology Co., Ltd
Tel
+86-15350571055
Email
Sibel@chuanghaibio.com
Country
China
ProdList
6085
Advantage
58

1642333-05-8, 22-(tert-Butoxy)-22-oxodocosanoic acidRelated Search:

OCTADECANEDIOIC ACID MONO-TERT-BUTYL ESTER 1643852-37-2 DIMETHYL OCTADECANEDIOATE Octadecanedioic acid, 1-methyl ester Heptadecanedioic acid mono-tert-butyl ester

  • 22-(tert-Butoxy)-22-oxodocosanoic acid
  • Docosanedioic acid, 1-(1,1-dimethylethyl) ester
  • Docosanedioic acid, mono(1,1-dimethylethyl) ester
  • 22-(tert-butoxy)-22-oxoicosanoic acid
  • 1642333-05-8