ChemicalBook > CAS DataBase List > 3-MORPHOLIN-4-YL-PROPIONIC ACID

3-MORPHOLIN-4-YL-PROPIONIC ACID

Product Name
3-MORPHOLIN-4-YL-PROPIONIC ACID
CAS No.
4497-04-5
Chemical Name
3-MORPHOLIN-4-YL-PROPIONIC ACID
Synonyms
AKOS BB-5602;AKOS BBS-00002594;BUTTPARK 145\04-88;CHEMBRDG-BB 4010141;RARECHEM AL BO 1512;TIMTEC-BB SBB010411;4-MORPHOLINEPROPIONIC ACID;4-MORPHOLINEPROPANOIC ACID;3-Morpholin-4-yl-propionicaci;3-MORPHOLIN-4-YLPROPANOIC ACID
CBNumber
CB4483539
Molecular Formula
C7H13NO3
Formula Weight
159.18
MOL File
4497-04-5.mol
More
Less

3-MORPHOLIN-4-YL-PROPIONIC ACID Property

Melting point:
74-76 °C
Boiling point:
174-176 °C(Press: 2 Torr)
Density 
1.159±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.74±0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C7H13NO3/c9-7(10)1-2-8-3-5-11-6-4-8/h1-6H2,(H,9,10)
InChIKey
YUYHRSGXZZVNMS-UHFFFAOYSA-N
SMILES
N1(CCC(O)=O)CCOCC1
CAS DataBase Reference
4497-04-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

AK Scientific
Product number
X3841
Product name
3-Morpholin-4-ylpropanoicacid
Packaging
1g
Price
$71
Updated
2021/12/16
SynQuest Laboratories
Product number
4H21-9-32
Product name
3-Morpholinopropanoic acid hydrobromide
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
019572
Product name
3-Morpholin-4-yl-propionic acid
Packaging
500mg
Price
$182
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0023908
Product name
3-MORPHOLINOPROPANOIC ACID
Purity
95.00%
Packaging
0.5G
Price
$770
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0023908
Product name
3-MORPHOLINOPROPANOIC ACID
Purity
95.00%
Packaging
1G
Price
$866.25
Updated
2021/12/16
More
Less

3-MORPHOLIN-4-YL-PROPIONIC ACID Chemical Properties,Usage,Production

Synthesis

33611-43-7

4497-04-5

The general procedure for the synthesis of 3-(4-morpholino)propionic acid from methyl 3-morpholino propionate was as follows: potassium hydroxide (485 mg, 8.6 mmol) was added to a solution of methyl 3-morpholino propionate (1 g, 5.7 mmol) in ethanol (20 mL) and the mixture was stirred for 2 hr at 80°C. The reaction was carried out using the same method as that used for the synthesis of methyl 3-morpholino propionate. Upon completion of the reaction, the solution was allowed to cool to room temperature and the pH was adjusted to 1 with 6 M hydrochloric acid. insoluble material was removed by filtration, and the volatiles in the filtrate were subsequently removed by evaporation. The resulting oil was ground with ether, the solid product was collected by filtration, washed with dichloromethane and dried under vacuum to give 3-morpholino propionic acid (993 mg, 89% yield) as a white solid. The structure of the product was confirmed by 1H NMR spectroscopy (DMSO-d6; CF3COOD): δ 2.83 (t, 2H), 3.13 (t, 2H), 3.36 (t, 2H), 3.46 (d, 2H), 3.73 (t, 2H), 3.97 (d, 2H). Mass spectrometry analysis (MS-ESI) showed a molecular ion peak of 159 [MH]+.

References

[1] Patent: US6184225, 2001, B2
[2] Journal of Medicinal Chemistry, 1993, vol. 36, # 3, p. 320 - 330
[3] Patent: US2008/9491, 2008, A1. Location in patent: Page/Page column 15
[4] RSC Advances, 2017, vol. 7, # 75, p. 47297 - 47308

3-MORPHOLIN-4-YL-PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Chloroform 1,4-Dioxane Hydrochloric acid Dichloromethane Methanol Sodium hydroxide Methyl acrylate Isopropylamine Morpholine

Preparation Products

More
Less

3-MORPHOLIN-4-YL-PROPIONIC ACID Suppliers

China 56 France 1 Germany 4 India 1 Russia 2 Switzerland 1 Ukraine 1 United Kingdom 3 United States 15 Global 84
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ：245797092
Email
market@gianthx.com
Country
China
ProdList
4505
Advantage
56
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
ForeChem (Nantong) Technology Co.,Ltd.
Tel
513-85982855 18921614129
Fax
051385915507
Email
sales@xianxingpharm.com
Country
China
ProdList
2986
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
skychemical Co.Ltd
Tel
021-20958197 20965099
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
1183
Advantage
57
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
Tel
+86-021-61727342 13611721451
Fax
021-61294107
Email
chainpharm@163.com
Country
China
ProdList
980
Advantage
58
Aloespharm Co., Ltd.
Tel
021-20960837
Fax
021-20960837
Email
market@aloespharm.com
Country
China
ProdList
1302
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6874
Advantage
55
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
skychemical Co.Ltd
Tel
021-20960837,QQ1332204249
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
3341
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Nanjing KaiMubo Pharmaceutical Co., Ltd.
Tel
025-66162170
Fax
025-66162170
Country
China
ProdList
7181
Advantage
55
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
14948
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000
Email
admin@jingshipharmatech.com
Country
China
ProdList
9853
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
10083
Advantage
58
Win-Win chemical CO., Limited
Tel
+86-0086-577-64498589 +86-15355981851
Fax
0086-577-56994596
Email
sales@win-winchemical.com
Country
China
ProdList
14359
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Beijing Haite lesk Technology Co., Ltd
Tel
15210893940; 15116916250
Fax
QQ: 237008221
Email
chemistryliu@163.com
Country
China
ProdList
7327
Advantage
58
Shanghai Qianlai Pharmaceutical Technology Co., Ltd.
Tel
021-57216911 17740831186
Email
482109853@qq.com
Country
China
ProdList
462
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9948
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Shanghai F.R. Chemical Technology Co.,Ltd
Tel
021-52230662 13795399395
Email
seaman79@126.com
Country
China
ProdList
268
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Hubei Hannuo Pharmaceutical Technology Co., Ltd
Tel
18662190603
Email
437347250@qq.com
Country
China
ProdList
7325
Advantage
58
Hubei Tuobang Chemical Co., Ltd.
Tel
13986192185 13986192185
Email
1466039@qq.com
Country
China
ProdList
9894
Advantage
58
Hubei Chenghai Chemical Co., Ltd
Tel
027-59220433 18327245847
Email
1400838877@qq.com
Country
China
ProdList
9875
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
Baoji Didu Pharmaceutical and Chemical Co., Ltd
Tel
029-81145305 17791533577
Email
1021@dideu.com
Country
China
ProdList
10009
Advantage
58
BEIJINGYIWANJINGRUI
Tel
15866847540
Email
dengyt2000@163.com
Country
China
ProdList
4100
Advantage
58
Hunan Hui Bai Yi New Materials Co., Ltd
Tel
0745-2866551 19976851779
Email
3002713163@qq.com
Country
China
ProdList
7333
Advantage
58
Shaanxi Linbang Industrial Co., Ltd
Tel
17709134430
Email
2379795542@qq.com
Country
China
ProdList
4822
Advantage
58
Shanghai Titan Scientific Co.,Ltd
Tel
16621234537
Email
chenyj@titansci.com
Country
China
ProdList
10000
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49934
Advantage
58

4497-04-5, 3-MORPHOLIN-4-YL-PROPIONIC ACIDRelated Search:

ETHYL 3-(4-MORPHOLINO)PROPIONATE METHYL 3-MORPHOLINOPROPIONATE 3-(2,6-DIMETHYL-MORPHOLIN-4-YL)-PROPIONIC ACID 3-(4-MORPHOLINYL)BUTANOIC ACID ETHYL 3-(2,6-DIMETHYLMORPHOLINO)PROPIONATE 3-MORPHOLIN-4-YL-PROPIONIC ACID 2-METHYL-3-MORPHOLIN-4-YL-PROPIONIC ACIDHYDROCHLORIDE 2-(MORPHOLINOMETHYL)ACRYLIC ACID 2-METHYL-3-MORPHOLIN-4-YL-PROPIONIC ACID 3-MORPHOLINOPROPANOIC ACID HYDRBROMIDE SALT 3-MORPHOLIN-3-YL-PROPIONIC ACID METHYL ESTER 3-MORPHOLIN-4-YL-PROPIONIC ACID HCL,3-MORPHOLIN-4-YL-PROPIONIC ACID HYDROCHLORIDE,3-MORPHOLIN-4-YL-PROPIONIC ACID X HCL >98% 3-MORPHOLIN-4-YL-PROPIONIC ACID HYDRAZIDE 2-MORPHOLIN-4-YL-PROPIONIC ACID 3-(2,6-DIMETHYL-MORPHOLIN-4-YL)-PROPIONIC ACIDHYDROCHLORIDE AURORA KA-4881 AURORA 7092 RARECHEM AL BO 0382

  • 3-morpholin-4-ium-4-ylpropanoate
  • TIMTEC-BB SBB010411
  • RARECHEM AL BO 1512
  • 3-(4-MORPHOLINYL)PROPIONIC ACID
  • 4-MORPHOLINEPROPANOIC ACID
  • 4-MORPHOLINEPROPIONIC ACID
  • 3-MORPHOLIN-4-YL-PROPIONIC ACID
  • 3-MORPHOLIN-4-YLPROPANOIC ACID
  • CHEMBRDG-BB 4010141
  • BUTTPARK 145\04-88
  • 3-Morpholinopropanoic Acid Hydrobromic Salt
  • 3-(4-Morpholinyl)propanoic acid
  • AKOS BB-5602
  • AKOS BBS-00002594
  • 3-morpholin-4-ylpropanoic acid(SALTDATA: HCl)
  • 3-Morpholin-4-Yl-Propionic Acid/6319-95-5
  • 3-Morpholin-4-yl-propionicaci
  • 4497-04-5