ChemicalBook > CAS DataBase List > PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
- Product Name
- PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
- CAS No.
- 39024-57-2
- Chemical Name
- PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
- Synonyms
- LHG-17;[Leu15]-HG-17;[LEU15]-GASTRIN I;gastrin I, human Leu15;(LEU15)-GASTRIN I (HUMAN);(Leu??)-Gastrin I (human);[Leucine15]-Little gastrin I;(Leu15)-Gastrin-17 I (human);[15-leucine]gastrin I, human;(15-LEUCINE) HUMAN GASTRIN I
- CBNumber
- CB4485427
- Molecular Formula
- C98H126N20O31
- Formula Weight
- 2080.2
- MOL File
- 39024-57-2.mol
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PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Property
- Boiling point:
- 2368.8±65.0 °C(Predicted)
- Density
- 1.400±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- 4.20±0.10(Predicted)
- BRN
- 5227423
- Sequence
- Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- G9145
- Product name
- [Leu15]-Gastrin I human
- Purity
- ≥95% (HPLC)
- Packaging
- 0.1mg
- Price
- $108
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- G9145
- Product name
- [Leu15]-Gastrin I human
- Purity
- ≥95% (HPLC)
- Packaging
- 0.5mg
- Price
- $376
- Updated
- 2024/03/01
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PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Chemical Properties,Usage,Production
Uses
Gastrin has been used:
- as a medium supplement establish enteroid cultures
- as a supplement to standard Dulbecco′s Modified Eagle Medium (DMEM) culture medium, human minigut medium to establish the growth of crypts.
General Description
GAST gene encodes for the protein [Leu15]-Gastrin I in human. In human chromosome, the gene GAST is localized on 17q21.2. G cells in the stomach antrum produces the precursor of [Leu15]-Gastrin I, progastrin. Progastrin undergoes cleavage and processing to yield gastrin, which is trophic for the entire gastrointestinal epithelium. Gastrin is essential for the growth of the digestive system and stimulates the production of gastric acid by parietal cells. Gastrin exerts its function through G-protein-coupled receptor called the cholecystokinin (CCK) or CCK-B receptor (CCK-BR). Gastrin release is stimulated by food, especially protein diet and is inhibited by very low pH. Atrophic gastritis, a Helicobacter pylori infection and long-term administration of proton pump inhibitors infection may cause overexpression of gastrin. Gastric adenocarcinoma show high levels of gastrin.
Biochem/physiol Actions
Gastrin I analog with full biological activity and improved stability in aqueous solutions. Leu15 replaces Met15, that is readily oxidized resulting in loss of biological activity.
PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Suppliers
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View Lastest Price from PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 manufacturers
Career Henan Chemical Co
- Product
- PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 39024-57-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-16
39024-57-2, PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2Related Search:
Gastrin I (1-14), human (TFA)
GLUCAGON (1-37) (PORCINE)
Gastrin I (rat)
3-(3-iodo-4-hydroxyphenyl)propionyl(Leu(15))gastrin-(5-17)
H-ASP-PHE-NH2
OTAVA-BB 7020692861
H-LEU-BETA-ALA-OH
Desglugastrin
PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
[LEU15]-GASTRIN, 5-17