PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2

Product Name: PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
CAS No.: 39024-57-2
Chemical Name: PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2
Synonyms: LHG-17;[Leu15]-HG-17;[LEU15]-GASTRIN I;gastrin I, human Leu15;(LEU15)-GASTRIN I (HUMAN);(Leu??)-Gastrin I (human);[Leucine15]-Little gastrin I;(Leu15)-Gastrin-17 I (human);[15-leucine]gastrin I, human;(15-LEUCINE) HUMAN GASTRIN I
CBNumber: CB4485427
Molecular Formula: C98H126N20O31
Formula Weight: 2080.2
MOL File: 39024-57-2.mol

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PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Property

Boiling point:: 2368.8±65.0 °C(Predicted)
Density: 1.400±0.06 g/cm3(Predicted)
storage temp.: −20°C
pka: 4.20±0.10(Predicted)
form: Solid
color: White to off-white
BRN: 5227423
Sequence: Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G9145
Product name: [Leu15]-Gastrin I human
Purity: ≥95% (HPLC)
Packaging: 0.1mg
Price: $108
Updated: 2024/03/01

Sigma-Aldrich

Product number: G9145
Product name: [Leu15]-Gastrin I human
Purity: ≥95% (HPLC)
Packaging: 0.5mg
Price: $376
Updated: 2024/03/01

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PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Chemical Properties,Usage,Production

Uses

Gastrin has been used:

as a medium supplement establish enteroid cultures
as a supplement to standard Dulbecco′s Modified Eagle Medium (DMEM) culture medium, human minigut medium to establish the growth of crypts.

General Description

GAST gene encodes for the protein [Leu15]-Gastrin I in human. In human chromosome, the gene GAST is localized on 17q21.2. G cells in the stomach antrum produces the precursor of [Leu15]-Gastrin I, progastrin. Progastrin undergoes cleavage and processing to yield gastrin, which is trophic for the entire gastrointestinal epithelium. Gastrin is essential for the growth of the digestive system and stimulates the production of gastric acid by parietal cells. Gastrin exerts its function through G-protein-coupled receptor called the cholecystokinin (CCK) or CCK-B receptor (CCK-BR). Gastrin release is stimulated by food, especially protein diet and is inhibited by very low pH. Atrophic gastritis, a Helicobacter pylori infection and long-term administration of proton pump inhibitors infection may cause overexpression of gastrin. Gastric adenocarcinoma show high levels of gastrin.

Biochem/physiol Actions

Gastrin I analog with full biological activity and improved stability in aqueous solutions. Leu15 replaces Met15, that is readily oxidized resulting in loss of biological activity.

PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 Suppliers

China 55 Switzerland 1 The Netherlands 1 United States 9 Global 66

SIGMA-RBI

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Country: Switzerland
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View Lastest Price from PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 manufacturers

Career Henan Chemical Co

Product: PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 39024-57-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-16

39024-57-2, PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2Related Search:

Gastrin I (1-14), human (TFA) GLUCAGON (1-37) (PORCINE) Gastrin I (rat) 3-(3-iodo-4-hydroxyphenyl)propionyl(Leu(15))gastrin-(5-17) H-ASP-PHE-NH2 OTAVA-BB 7020692861 H-LEU-BETA-ALA-OH Desglugastrin PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2 [LEU15]-GASTRIN, 5-17

H-PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2

[LEU15]-GASTRIN I

(LEU15)-GASTRIN I (HUMAN)

PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2

PGLU-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-LEU-ASP-PHE-NH2

leu(15)-gastrinheptadecapeptid

18-(5-Oxo-L-proline)-22-L-leucine-32-L-leucine-18-34-gastrinI【pig】

5-Oxo-L-Pro-Gly-L-Pro-L-Trp-L-Leu-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Leu-L-Asp-L-Phe-NH2

(Leu15)-Gastrin I (huMan) (Leu15)-Gastrin-17 I (huMan), (Pyr18,Leu22,Leu32)-Gastrin I (18-34) (porcine)

(Leu15)-Gastrin-17 I (huMan), (Pyr18,Leu22,Leu32)-Gastrin I (18-34) (porcine)

[18-Pyroglutamic acid, 32-leucine]-Big gastrin I-(18-34)-peptide amide, human

[Leu15]-HG-17

[Leucine15]-Gastrin I heptadecapeptide

[Leucine15]-Little gastrin I

LHG-17

(Leu15)-Gastrin-17 I (human)

18-34-Gastrin I (pig), 18-(5-oxo-l-proline)-22-l-leucine-32-l-leucine-

[15-leucine]-gastrin i, human heptadecapeptide

gastrin heptadecapeptide, Leu(15)-

gastrin I, human Leu15

[15-leucine]gastrin I, human

[15-Leucine]-Gastrin I, human heptadecapeptide, [Leu15]-Gastrin I, human, [Leu15]-HG-17, [Leucine15]-Gastrin I heptadecapeptide, [Leucine15]-Little gastrin I, LHG-17, [18-Pyroglutamic acid, 32-leucine]-Big gastrin I-(18-34)-peptide amide, human

(15-LEUCINE) HUMAN GASTRIN I

L-Phenylalaninamide, 5-oxo-L-prolylglycyl-L-prolyl-L-tryptophyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-tyrosylglycyl-L-tryptophyl-L-leucyl-L-α-aspartyl-

Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2

(Leu??)-Gastrin I (human)

39024-57-2

C98H126N20O31

Gastrins

Gastrointestinal Products

Peptides

BioChemical

Amino Acids and Peptides

Biochemicals and Reagents