N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide

Product Name: N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide
CAS No.: 1816989-16-8
Chemical Name: N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide
Synonyms: SY-1365;Mevociclib;Mevociclib，SY-1365;SY-1365;SY 1365;SY1365;N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide;N-[(1S,3R)-3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-1-methylcyclohexyl]-5-[(2E)-4-(dimethylamino)but-2-enamido]pyridine-2-carboxamide;N-[(1S,3R)-3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-2-pyridinecarboxamide;Inhibitor,triple negative breast cancer,TNBC,Mevociclib,Cyclin dependent kinase,SY1365,tumors,cancers,cell,inhibit,solid,CDK,small,SY 1365,CDK7/CycH/MAT1,lung;2-Pyridinecarboxamide, N-[(1S,3R)-3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-
CBNumber: CB44869298
Molecular Formula: C31H35ClN8O2
Formula Weight: 587.11
MOL File: 1816989-16-8.mol

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N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Property

Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 125 mg/mL (212.90 mM)
form: Solid
pka: 12.04±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0095954
Product name: Mevociclib
Purity: 99.27%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0095954
Product name: Mevociclib
Purity: 99.27%
Packaging: 10mg
Price: $650
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611907
Product name: SY-1365
Purity: >98%
Packaging: 50mg
Price: $1802
Updated: 2021/12/16

ChemScene

Product number: CS-0095954
Product name: Mevociclib
Purity: 99.27%
Packaging: 50mg
Price: $2000
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611907
Product name: SY-1365
Purity: >98%
Packaging: 100mg
Price: $2839
Updated: 2021/12/16

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N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Chemical Properties,Usage,Production

Uses

N-[(1S,3R)-3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-2-pyridinecarboxamide is a CDK7 inhibitor and is used for anticancer treatments.

N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide Suppliers

China 24 United States 4 Global 28

ShangHai Caerulum Pharma Discovery Co., Ltd.

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Shanghai YuanQi Biotechnology Co., Ltd.

Tel: +86-2332782371 +86-18120098618
Email: sales@adobechem.com
Country: China
ProdList: 1250
Advantage: 50

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: lucy@atkchemical.com
Country: China
ProdList: 9987
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Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
Country: United States
ProdList: 32159
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InvivoChem

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Fax: 708-557-7486
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Country: United States
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Advantage: 58

DC Chemicals

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Country: China
ProdList: 9409
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Changzhou Chenhong Biotechnology Co., Ltd.

Tel: 0519-85788828 13775037613
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
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Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15342225168
Email: yutianchun2007@126.com
Country: China
ProdList: 10003
Advantage: 58

1816989-16-8, N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamideRelated Search:

N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide

SY-1365

SY-1365;SY 1365;SY1365

2-Pyridinecarboxamide, N-[(1S,3R)-3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-

N-[(1S,3R)-3-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-1-methylcyclohexyl]-5-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-2-pyridinecarboxamide

Mevociclib

Mevociclib，SY-1365

Inhibitor,triple negative breast cancer,TNBC,Mevociclib,Cyclin dependent kinase,SY1365,tumors,cancers,cell,inhibit,solid,CDK,small,SY 1365,CDK7/CycH/MAT1,lung

N-[(1S,3R)-3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-1-methylcyclohexyl]-5-[(2E)-4-(dimethylamino)but-2-enamido]pyridine-2-carboxamide

1816989-16-8

C31H35ClN8O2